Transcriptional regulation in the context of chromatin structure

Crystal structure of the nucleosome core particle at 2.8 Å resolution

1997 • 8,906 citations

The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases

1996 • 2,873 citations

A Mammalian Histone Deacetylase Related to the Yeast Transcriptional Regulator Rpd3p

1996 • 1,769 citations

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

1996 • 1,457 citations

The nucleosomal core histone octamer at 3.1 A resolution: a tripartite protein assembly and a left-handed superhelix.

1991 • 720 citations

The TAFII250 Subunit of TFIID Has Histone Acetyltransferase Activity

1996 • 705 citations

Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex

1998 • 507 citations

Acetylation of histone H4 plays a primary role in enhancing transcription factor binding to nucleosomal DNA in vitro.

1996 • 469 citations

Comparison of the Complete Protein Sets of Worm and Yeast: Orthology and Divergence

1998 • 447 citations

The SWI-SNF complex: a chromatin remodeling machine?

1995 • 379 citations

Binding of the winged-helix transcription factor HNF3 to a linker histone site on the nucleosome

1998 • 373 citations

dMi-2, a Hunchback-Interacting Protein That Functions in Polycomb Repression

1998 • 349 citations

TAFs mediate transcriptional activation and promoter selectivity

1996 • 334 citations

Essential and redundant functions of histone acetylation revealed by mutation of target lysines and loss of the Gcn5p acetyltransferase

1998 • 318 citations

The yeast SNF2/SWI2 protein has DNA-stimulated ATPase activity required for transcriptional activation.

1993 • 299 citations

Change in the pattern of histone binding to DNA upon transcriptional activation

1989 • 246 citations

Amino acid substitutions in the structured domains of histones H3 and H4 partially relieve the requirement of the yeast SWI/SNF complex for transcription.

1995 • 245 citations

Specific regulation of Xenopus chromosomal 5S rRNA gene transcription in vivo by histone H1.

1994 • 228 citations

The transcriptionally-active MMTV promoter is depleted of histone H1

1992 • 222 citations

A nucleosome-dependent static loop potentiates estrogen-regulated transcription from the Xenopus vitellogenin B1 promoter in vitro.

1993 • 219 citations

A histone octamer-like structure within TFIID

1996 • 182 citations

Nucleosome-mediated disruption of transcription factor-chromatin initiation complexes at the mouse mammary tumor virus long terminal repeat in vivo.

1994 • 128 citations