Effect of MPEP treatment on brain-derived neurotrophic factor gene expression.

Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments

1995 • 2,090 citations

Brain-Derived Neurotrophic Factor Produces Antidepressant Effects in Behavioral Models of Depression

2002 • 1,627 citations

Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways

2002 • 1,612 citations

Activation of the TrkB Neurotrophin Receptor Is Induced by Antidepressant Drugs and Is Required for Antidepressant-Induced Behavioral Effects

2003 • 783 citations

Neuronal plasticity and survival in mood disorders

2000 • 658 citations

Activation of Metabotropic Glutamate Receptor 5 Has Direct Excitatory Effects and Potentiates NMDA Receptor Currents in Neurons of the Subthalamic Nucleus

2000 • 414 citations

Glutamate and Depression

2003 • 404 citations

Potential anxiolytic‐ and antidepressant‐like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist

2001 • 311 citations

Differential regulation of Brain Derived Neurotrophic Factor transcripts by antidepressant treatments in the adult rat brain

2003 • 274 citations

Bi-phasic change in BDNF gene expression following antidepressant drug treatment

2003 • 244 citations

Multiple MPEP administrations evoke anxiolytic- and antidepressant-like effects in rats

2002 • 154 citations

The Neuroprotective Agent Memantine Induces Brain-Derived Neurotrophic Factor and trkB Receptor Expression in Rat Brain

2001 • 146 citations

Regulation of BDNF expression in primary neuron culture by LY392098, a novel AMPA receptor potentiator

2001 • 104 citations

Evidence that the metabotropic glutamate receptor 5 antagonist MPEP may act as an inhibitor of the norepinephrine transporter in vitro and in vivo

2003 • 73 citations

Combined treatment with imipramine and metyrapone induces hippocampal and cortical brain-derived neurotrophic factor gene expression in rats.

2005 • 38 citations

A role for glutamate in the treatment of anxiety and depression: Focus on group I metabotropic glutamate (mGlu) receptors

2002 • 23 citations