Different Roles of the CD2 and LFA-1 T-Cell Co-receptors for Regulating Cytotoxic, Proliferative, and Cytokine Responses of Human Vγ9/Vδ2 T Cells

Adhesion receptors of the immune system

1990 • 6,585 citations

Serial triggering of many T-cell receptors by a few peptide–MHC complexes

1995 • 1,143 citations

The Lymphocyte Function Associated LFA-1, CD2, and LFA-3 Molecules: Cell Adhesion Receptors of the Immune System

1987 • 1,104 citations

Natural and synthetic non-peptide antigens recognized by human γδ T cells

1995 • 974 citations

Gamma/Delta Cells

1993 • 819 citations

An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2

1987 • 699 citations

Direct presentation of nonpeptide prenyl pyrophosphate antigens to human γδ T cells

1995 • 468 citations

Phosphatidylinositol 3-Kinase Couples the Interleukin-2 Receptor to the Cell Cycle Regulator E2F

1997 • 411 citations

Distinct Roles for LFA-1 and CD28 during Activation of Naive T Cells: Adhesion versus Costimulation

1997 • 411 citations

Human γδ T Cells Recognize Alkylamines Derived from Microbes, Edible Plants, and Tea

1999 • 368 citations

Recognition by Human V _γ 9/V _δ 2 T Cells of a GroEL Homolog on Daudi Burkitt's Lymphoma Cells

1990 • 357 citations

Recombinant interleukin-2 directly augments the cytotoxicity of human monocytes

1987 • 301 citations

Monoclonal antibody to a novel lymphocyte function-associated antigen (LFA-1): mechanism of blockade of T lymphocyte-mediated killing and effects on other T and B lymphocyte functions.

1981 • 292 citations

V gamma 2V delta 2 TCR-dependent recognition of non-peptide antigens and Daudi cells analyzed by TCR gene transfer.

1995 • 276 citations

Serial triggering of TCRs: a basis for the sensitivity and specificity of antigen recognition

1997 • 235 citations

The two-signal model of lymphocyte activation twenty-one years later

1992 • 233 citations

Anchoring mechanisms for LFA-3 cell adhesion glycoprotein at membrane surface

1987 • 220 citations

CD2-mediated adhesion facilitates T lymphocyte antigen recognition function

1989 • 209 citations

Gamma/delta T cell clones and natural killer cell clones mediate distinct patterns of non-major histocompatibility complex-restricted cytolysis.

1990 • 176 citations

Sentinel function of broadly reactive human γδ T cells

1997 • 156 citations

The Structural Biology of CD2

1989 • 154 citations

Gamma/Delta T Cells

1993 • 146 citations

A role for phosphatidylinositol 3-kinase in the regulation of beta 1 integrin activity by the CD2 antigen.

1995 • 111 citations

Primary gamma delta cell clones can be defined phenotypically and functionally as Th1/Th2 cells and illustrate the association of CD4 with Th2 differentiation.

1998 • 105 citations

The CD3 zeta cytoplasmic domain mediates CD2-induced T cell activation.

1992 • 82 citations

Primary γδ Cell Clones Can Be Defined Phenotypically and Functionally as Th1/Th2 Cells and Illustrate the Association of CD4 with Th2 Differentiation

1998 • 79 citations

Gamma/delta T lymphocytes in viral Infections

1995 • 79 citations

TCRgammadelta Cells: A Specialized T-Cell Subset in the Immune System

1995 • 76 citations

Nonspecific inhibitor released by T acceptor cells reduces the production of interleukin-2

1982 • 72 citations

Acquired immunological tolerance of foreign cells is impaired by recombinant interleukin 2 or vitamin A acetate.

1985 • 72 citations

T cell receptor-triggered activation of intraepithelial lymphocytes in vitro

1993 • 57 citations

Innate T-cell immunity to nonpeptidic antigens

1998 • 54 citations

Selective activation of gamma/delta + T cell clones by single anti-CD2 antibodies.

1991 • 34 citations

Glimpses at the recognition of peptide/MHC complexes by T‐cell antigen receptors

1998 • 26 citations

Both LFA‐1‐positive and ‐deficient T cell clones require the CD2/LFA‐3 interaction for specific cytolytic activation

1992 • 17 citations

Identification of the TS2/18-recognized epitope on the CD2 molecule as a target for suppression of T cell cytokine synthesis.

1995 • 12 citations

Inhibitory effects of anti-CD2 monoclonal antibodies on interleukin 2 production and interleukin 2 receptor expression in anti-CD3-induced T cell activation

1989 • 5 citations