Loss of a Putative Tumor Suppressor Locus after Gamma-Ray-Induced Neoplastic Transformation of HeLa × Skin Fibroblast Human Cell Hybrids

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Mutation and Cancer: Statistical Study of Retinoblastoma

1971 • 7,335 citations

Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization.

1986 • 3,231 citations

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1992 • 3,092 citations

p53 function and dysfunction

1992 • 1,918 citations

Human Cell Hybrids: Analysis of Transformation and Tumorigenicity

1982 • 349 citations

The tumore suppressor p53

1993 • 336 citations

Suppression of malignancy in human cells

1976 • 313 citations

Introduction of human chromosome 11 via microcell transfer controls tumorigenic expression of HeLa cells.

1986 • 301 citations

Alkaline transfer of DNA to plastic membrane

1984 • 285 citations

HUMAN TUMOR SUPPRESSOR GENES

1990 • 266 citations

Gamma ray-induced loss of expression of HLA and glyoxalase I alleles in lymphoblastoid cells.

1980 • 257 citations

The WT1 Wilms tumor gene product: a developmentally regulated transcription factor in the kidney that functions as a tumor suppressor

1993 • 254 citations

Specific chromosome loss associated with the expression of tumorigenicity in human cell hybrids

1981 • 234 citations

Effect of gamma rays at the dihydrofolate reductase locus: Deletions and inversions

1986 • 233 citations

Normal human chromosome 11 suppresses tumorigenicity of human cervical tumor cell line SiHa

1989 • 144 citations

The retinoblastoma gene: role in cell cycle control and cell differentiation

1993 • 132 citations

Do radiation-induced thioguanine-resistant mutants of cultured mammalian cells arise by HGPRT gene mutation or X-chromosome rearrangement?

1978 • 126 citations

Tumor-suppressor p53 and the cell cycle

1993 • 120 citations

Implication of chromosome 11 in the suppression of neoplastic expression in human cell hybrids.

1986 • 108 citations

Suppression of tumorigenicity

1982 • 76 citations

A tumor-specific membrane phosphoprotein marker in human cell hybrids

1981 • 73 citations

Neoplastic transformation of immortalized human epidermal keratinocytes by ionizing radiation.

1990 • 67 citations

Suppression of tumorigenicity in somatic cell hybrids

1986 • 65 citations

Dissociation of anchorage independence from tumorigenicity in human cell hybrids

1980 • 64 citations

Re-analysis of radiation-induced specific locus mutations in the mouse

1976 • 61 citations

Loss of heterozygosity for alleles on chromosome II in cervical carcinoma.

1991 • 61 citations

Further Studies on the Radiation-Induced Expression of a Tumor-Specific Antigen in Human Cell Hybrids

1988 • 57 citations

Neoplastic Transformation of Human Hybrid Cells by γ Radiation: A Quantitative Assay

1987 • 57 citations

Localization of HeLa cell tumor-suppressor gene to the long arm of chromosome II.

1989 • 57 citations

Human placental and intestinal alkaline phosphatase genes map to 2q34-q37.

1987 • 56 citations

Characterization of intestinal alkaline phosphatase expression and the tumorigenic potential of gamma-irradiated HeLa x fibroblast cell hybrids.

1991 • 51 citations

Identification of the HeLa tumor-associated antigen, p75/150, as intestinal alkaline phosphatase and evidence for its transcriptional regulation.

1990 • 49 citations

Deletion and translocation of chromosome 11q13 sequences in cervical carcinoma cell lines.

1995 • 49 citations

Unraveling the Function of the Retinoblastoma Gene

1993 • 49 citations

A Simplified and Rapid Staining Method for the HeLa × Skin Fibroblast Human Hybrid Cell Neoplastic Transformation Assay

1992 • 46 citations

Fission-neutron-induced Expression of a Tumour-associated Antigen in Human Cell Hybrids (HeLa × Skin Fibroblast): Evidence for Increased Expression at Low Dose Rate

1990 • 28 citations

Radiation-induced deletion of chromosomal regions containing tumor suppressor genes in human bronchial epithelial cells

1993 • 21 citations

Monoclonal Antibodies Specific for a Tumor-Associated Membrane Phosphoprotein in Human Cell Hybrids

1985 • 15 citations

An important step in radiation carcinogenesis may be inactivation of cellular genes

1989 • 13 citations

Suppression of radiation-induced neoplastic transformation of human cell hybrids by long term incubation at low extracellular pH.

1990 • 12 citations

Rearrangement of chromosome band 11q13 in HeLa cells.

1994 • 9 citations

Isolation of human cell hybrids (HeLa × skin fibroblast) expressing a radiation-induced tumour-associated antigen

1989 • 9 citations

Structural and functional features of a cell surface phosphoglycoprotein associated with tumorigenic phenotype in human fibroblast x HeLa cell hybrids.

1986 • 8 citations

Radiation-Induced Neoplastic Transformation of Human Cell Hybrids

1987 • 7 citations

UVC-induced expression of a tumor-associated antigen in human cell hybrids (HeLa × skin fibroblasts): repair of potentially lethal and potentially transforming damage

1989 • 6 citations