Vitamin D and Osteoporosis
Data up to Jan 2025
Total Citations Per Year
Abstract
References (197)
Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures
1996 • 3,809 citations
Reduction of Vertebral Fracture Risk in Postmenopausal Women With Osteoporosis Treated With Raloxifene<SUBTITLE>Results From a 3-Year Randomized Clinical Trial</SUBTITLE>
1999 • 3,362 citations
Vitamin D3and Calcium to Prevent Hip Fractures in Elderly Women
1992 • 2,963 citations
Effects of Risedronate Treatment on Vertebral and Nonvertebral Fractures in Women With Postmenopausal Osteoporosis<SUBTITLE>A Randomized Controlled Trial</SUBTITLE>
1999 • 2,473 citations
Effect of Calcium and Vitamin D Supplementation on Bone Density in Men and Women 65 Years of Age or Older
1997 • 2,320 citations
Effect of Oral Alendronate on Bone Mineral Density and the Incidence of Fractures in Postmenopausal Osteoporosis
1995 • 2,293 citations
Effect of Alendronate on Risk of Fracture in Women With Low Bone Density but Without Vertebral Fractures<SUBTITLE>Results From the Fracture Intervention Trial</SUBTITLE>
1998 • 2,283 citations
Sex Steroids and the Construction and Conservation of the Adult Skeleton
2002 • 1,688 citations
Randomized Trial of the Effects of Risedronate on Vertebral Fractures in Women with Established Postmenopausal Osteoporosis
2000 • 1,593 citations
Aging decreases the capacity of human skin to produce vitamin D3.
1985 • 1,404 citations
Effect of four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: randomised double blind controlled trial
2003 • 1,281 citations
A Unitary Model for Involutional Osteoporosis: Estrogen Deficiency Causes Both Type I and Type II Osteoporosis in Postmenopausal Women and Contributes to Bone Loss in Aging Men
1998 • 1,142 citations
A randomized trial of nasal spray salmon calcitonin in postmenopausal women with established osteoporosis: the prevent recurrence of osteoporotic fractures study
2000 • 1,131 citations
The Role of the Vitamin D Endocrine System in Health and Disease
1989 • 1,041 citations
Calcium Absorption Varies within the Reference Range for Serum 25-Hydroxyvitamin D
2003 • 989 citations
Effects of Vitamin D and Calcium Supplementation on Falls: A Randomized Controlled Trial
2003 • 989 citations
A Controlled Trial of the Effect of Calcium Supplementation on Bone Density in Postmenopausal Women
1990 • 963 citations
Relationship of Serum Sex Steroid Levels and Bone Turnover Markers with Bone Mineral Density in Men and Women: A Key Role for Bioavailable Estrogen1
1998 • 915 citations
Intestinal Calcium Absorption and Serum Vitamin D Metabolites in Normal Subjects and Osteoporotic Patients
1979 • 865 citations
Serum vitamin D concentrations among elderly people in Europe
1995 • 790 citations
Vitamin D Supplementation and Fracture Incidence in Elderly Persons
1996 • 650 citations
Differences in vitamin D status between countries in young adults and the elderly
1992 • 627 citations
Treatment of Postmenopausal Osteoporosis
1998 • 619 citations
The Influence of Age on the 24-Hour Integrated Concentration of Growth Hormone in Normal Individuals*
1985 • 600 citations
Effects of a Short-Term Vitamin D and Calcium Supplementation on Body Sway and Secondary Hyperparathyroidism in Elderly Women
2000 • 597 citations
Treatment of Postmenopausal Osteoporosis with Calcitriol or Calcium
1992 • 583 citations
Regulation by vitamin D metabolites of parathyroid hormone gene transcription in vivo in the rat.
1986 • 530 citations
Vitamin D and bone health in the elderly
1982 • 515 citations
Prevention of bone loss by vitamin D supplementation in elderly women: a randomized double-blind trial.
1995 • 457 citations
EFFECT OF AGE ON CALCIUM ABSORPTION
1970 • 450 citations
Effect of Estrogen on Calcium Absorption and Serum Vitamin D Metabolites in Postmenopausal Osteoporosis*
1980 • 433 citations
Are vitamin D receptor polymorphisms associated with bone mineral density? A meta-analysis
1996 • 421 citations
The Effect of Vitamin D Supplementation on Vitamin D Status and Parathyroid Function in Elderly Subjects*
1988 • 386 citations
Osteopathy and resistance to vitamin D toxicity in mice null for vitamin D binding protein
1999 • 381 citations
Calcium absorption in women: Relationships to Calcium intake, Estrogen status, and age
1989 • 375 citations
Deficient Production of 1,25-Dihydroxyvitamin D in Elderly Osteoporotic Patients
1981 • 373 citations
Annual injection of vitamin D and fractures of aged bones
1992 • 366 citations
Intestinal Calcium Absorption in Exogenous Hypercortisonism
1977 • 361 citations
Impaired vitamin D metabolism with aging in women. Possible role in pathogenesis of senile osteoporosis.
1984 • 360 citations
Increase in serum bone gamma-carboxyglutamic acid protein with aging in women. Implications for the mechanism of age-related bone loss.
1983 • 358 citations
Calcium intake and bone mass: A quantitative review of the evidence
1990 • 346 citations
Nutritional status in a healthy elderly population: vitamin C
1982 • 342 citations
An evaluation of the relative contributions of exposure to sunlight and of diet to the circulating concentrations of 25-hydroxyvitamin D in an elderly nursing home population in Boston
1990 • 329 citations
Free 1,25-dihydroxyvitamin D levels in serum from normal subjects, pregnant subjects, and subjects with liver disease.
1984 • 320 citations
VIII: Meta-Analysis of the Efficacy of Vitamin D Treatment in Preventing Osteoporosis in Postmenopausal Women
2002 • 314 citations
Calcitriol Treatment Is Not Effective in Postmenopausal Osteoporosis
1989 • 311 citations
Effect of Dietary Calcium and Age on Jejunal Calcium Absorption in Humans Studied by Intestinal Perfusion
1973 • 300 citations
Vitamin D status and sex hormone binding globulin: Determinants of bone turnover and bone mineral density in elderly women
1995 • 292 citations
Vitamin D Status and Related Parameters in a Healthy Population: The Effects of Age, Sex, and Season*
1990 • 278 citations
SUPPRESSION BY 1,25(OH)2D3OF TRANSCRIPTION OF THE PRE–PR0PARATHYR0ID HORMONE GENE
1986 • 248 citations
Estrogen Preserves a Normal Intestinal Responsiveness to 1,25-Dihydroxyvitamin D3in Oophorectomized Women*
1990 • 243 citations
The Rate of Bone Mineral Loss in Normal Men and the Effects of Calcium and Cholecalciferol Supplementation
1990 • 240 citations
Evidence of an age-related decrease in intestinal responsiveness to vitamin D: relationship between serum 1,25-dihydroxyvitamin D3 and intestinal vitamin D receptor concentrations in normal women.
1992 • 239 citations
Laboratory Values in Fit Aging Individuals--Sexagenarians through Centenarians
1992 • 239 citations
Chronic Sunscreen Use Decreases Circulating Concentrations of 25-Hydroxyvitamin D
1988 • 237 citations
Determinants of vitamin D status in patients with hip fracture and in elderly control subjects
1987 • 230 citations
1,25-Dihydroxyvitamin D3Suppresses Parathyroid Hormone Secretion from Bovine Parathyroid Cells in Tissue Culture*
1985 • 229 citations
Effects of 1?-hydroxyvitamin D3 on lumbar bone mineral density and vertebral fractures in patients with postmenopausal osteoporosis
1994 • 227 citations
Calcitriol in the treatment of postmenopausal osteoporosis
1988 • 223 citations
Intestinal Calcium Transporter Genes Are Upregulated by Estrogens and the Reproductive Cycle Through Vitamin D Receptor-Independent Mechanisms
2003 • 222 citations
Treatment of Postmenopausal Osteoporosis with High Doses of Synthetic Calcitriol
1990 • 219 citations
Nutritional status in a healthy elderly population: vitamin D
1982 • 217 citations
Vitamin D-endocrine system.
1985 • 217 citations
Combination Treatment with Estrogen and Calcitriol in the Prevention of Age-Related Bone Loss
2001 • 214 citations
An evaluation of the importance of gastric acid secretion in the absorption of dietary calcium.
1984 • 213 citations
Interrelationship among vitamin D metabolism, true calcium absorption, parathyroid function, and age in women: Evidence of an age-related intestinal resistance to 1,25-dihydroxyvitamin D action
1991 • 202 citations
The influence of age on the intestinal absorption of 47-Ca absorption in post-menopausal osteoporosis.
1965 • 193 citations
1,25-Dihydroxyvitamin D3: short- and long-term effects on bone and calcium metabolism in patients with postmenopausal osteoporosis.
1982 • 188 citations
Measurement of 25-hydroxyvitamin D in serum and its relation to sunshine, age and vitamin D intake in the Danish population
1979 • 185 citations
Calcium and vitamin D
2003 • 183 citations
Advancing Age Results in Reduction of Intestinal and Bone 1,25-Dihydroxyvitamin D Receptor
1990 • 180 citations
Increases in Immunoreactive Parathyroid Hormone with Age
1979 • 174 citations
A potent analog of 1α,25-dihydroxyvitamin D 3 selectively induces bone formation
2002 • 174 citations
Age-Related Changes in Parathyroid Hormone and Parathyroid Hormone Action in Normal Humans*
1984 • 174 citations
Growth Hormone and Bone
1993 • 172 citations
INHIBITION OF OSTEOLYTIC BONE LESIONS BY (3-AMINO-1-HYDROXYPROPYLIDENE)-1, 1-BISPHOSPHONATE (A.P.D.)
1979 • 172 citations
An investigation of sources of variation in calcium absorption efficiency.
1995 • 172 citations
Alterations in Calcium, Vitamin D, and Parathyroid Hormone Physiology in Normal Men with Aging: Relationship to the Development of Senile Osteopenia*
1986 • 170 citations
Gastric Emptying Rate in the Elderly: Implications for Drug Therapy
1981 • 166 citations
Age-Related Changes in Bone Turnover in Men
1999 • 162 citations
Calcium and vitamin D supplements: effects on calcium metabolism in elderly people
1987 • 160 citations
Changes in gastrointestinal function attributed to aging
1992 • 160 citations
Serum Vitamin D2and Vitamin D3Metabolite Concentrations and Absorption of Vitamin D2in Elderly Subjects*
1986 • 159 citations
Relationship between serum 25-hydroxyvitamin D and bone resorption markers in vitamin D insufficiency
2002 • 157 citations
The influence of age on bone mineral regulating hormones
1986 • 156 citations
Effects of estrogen on circulating "free" and total 1,25-dihydroxyvitamin D and on the parathyroid-vitamin D axis in postmenopausal women.
1989 • 154 citations
Role of parathyroid hormone in mediating nocturnal and age-related increases in bone resorption.
1995 • 149 citations
Reduced occurrence of vertebral crush fractures in senile osteoporosis treated with 1 alpha (OH)-vitamin D3.
1987 • 140 citations
Intestinal Cholecalciferol Absorption in the Elderly and in Younger Adults
1978 • 135 citations
Mechanism of renal calcium conservation with estrogen replacement therapy in women in early postmenopause--a clinical research center study.
1995 • 135 citations
The presence of functional estrogen receptors in intestinal epithelial cells.
1993 • 132 citations
Age-related Changes in Parathyroid Hormone and 25 Hydroxycholecalciferol Levels
1983 • 131 citations
Vitamin D receptor gene polymorphism, bone mass, body size, and vitamin D receptor density
1995 • 130 citations
A Double-Masked Multicenter Comparative Study Between Alendronate and Alfacalcidol in Japanese Patients with Osteoporosis
1999 • 125 citations
Influence of vitamin D on parathyroid function in the elderly.
1992 • 123 citations
The Effect of Calcitriol on Patients with Postmenopausal Osteoporosis with Special Reference to Fracture Frequency
1989 • 122 citations
Serum vitamin D metabolites and calcium absorption in normal young and elderly free-living women and in women living in nursing homes
1997 • 121 citations
Risk of fractures in patients with pernicious anemia
1992 • 121 citations
Evidence for estrogen receptor-linked calcium transport in the intestine
1993 • 118 citations
Calcium malabsorption in the elderly: the effect of treatment with oral 25‐hydroxyvitamin D3
1983 • 117 citations
Calcium and Vitamin D Supplementation Increases Spinal BMD in Healthy, Postmenopausal Women
1998 • 116 citations
Risk of Age-Related Fractures in Patients With Primary Hyperparathyroidism
1992 • 114 citations
THE DECLINE IN VITAMIN D STATUS WITH AGE
1980 • 112 citations
The effects of menopause and age on calcitropic hormones: A cross-sectional study of 655 healthy women aged 35 to 90
1995 • 111 citations
Early Postmenopausal Bone Loss is Not Associated with a Decrease in Circulating Levels of 25-Hydroxyvitamin D, 1,25-Dihydroxyvitamin D, or Vitamin D-Binding Protein*
1987 • 107 citations
Nyctohemeral changes in bone turnover assessed by serum bone Gla-protein concentration and urinary deoxypyridinoline excretion: effects of growth and ageing
1992 • 107 citations
Immunoradiometric assay of parathyrin with polyclonal and monoclonal region-specific antibodies
1990 • 104 citations
Journal of Bone and Mineral Research
1991 • 102 citations
Relationship of Intestinal Calcium Absorption to 1,25-Dihydroxyvitamin D [1,25(OH)2D] Levels in Young Versus Elderly Women: Evidence for Age-Related Intestinal Resistance to 1,25(OH)2D Action
2000 • 102 citations
Effect of 1,25‐dihydroxy ‐ vitamin D3 in itself or combined with hormone treatment in preventing postmenopausal osteoporosis
1981 • 100 citations
Bone mineral content in relation to lactation history in pre- and postmenopausal women
1991 • 99 citations
Biochemical parameters associated with low bone density in healthy men and women
1992 • 98 citations
Journal of Bone and Mineral Research
1991 • 92 citations
Age-related rise in parathyroid hormone in man: The use of intact and midmoleeule antisera to distinguish hormone secretion from retention
1987 • 87 citations
Effect of age on circulating immunoreactive and bioactive parathyroid hormone levels in women
1987 • 87 citations
Serum Vitamin D Metabolites and Their Binding Protein in Patients with Liver Cirrhosis
1984 • 87 citations
Partially Reversible Osteopenia After Surgery for Primary Hyperparathyroidism
1986 • 86 citations
Vitamin D supplementation in elderly nursing home residents increases 25(OH)D but not 1,25(OH)2D
1990 • 86 citations
Association Between Intestinal Vitamin D Receptor, Calcium Absorption, and Serum 1,25 Dihydroxyvitamin D in Normal Young and Elderly Women
1997 • 86 citations
Effect of Long Term Treatment with Calcitriol on Calcium Absorption and Mineral Metabolism in Postmenopausal Osteoporosis*
1985 • 86 citations
Effect of Age on Serum Immunoreactive Parathyroid Hormone and Its Biological Effects*
1981 • 84 citations
Progressive decrease of true intestinal calcium absorption with age in normal man.
1973 • 83 citations
Time course of calcium absorption in humans: Evidence for a colonic component
1989 • 80 citations
Long-term effect of nandrolone decanoate, 1 alpha-hydroxyvitamin D3 or intermittent calcium infusion therapy on bone mineral content, bone remodeling and fracture rate in symptomatic osteoporosis: a double-blind controlled study.
1986 • 76 citations
Episodic Fluctuation in Serum Intact Parathyroid Hormone Concentration in Men
1990 • 76 citations
Expression of Calbindin-D Decreases with Age in Intestine and Kidney*
1989 • 76 citations
Abnormalities of parathyroid hormone secretion in elderly women that are reversible by short term therapy with 1,25-dihydroxyvitamin D3.
1994 • 73 citations
Assessment of Plasma 25-Hydroxyvitamin D Response to Ultraviolet Irradiation over a Controlled Area in Young and Elderly Subjects
1980 • 71 citations
Calcium absorption in elderly subjects on high- and low-fiber diets: effect of gastric acidity
1991 • 71 citations
Effect of aging on vitamin D stores and bone density in women
1987 • 70 citations
RENAL IMPAIRMENT AND ITS EFFECTS ON CALCIUM METABOLISM IN ELDERLY WOMEN
1984 • 70 citations
Endocrinology and Metabolism in the Elderly
1992 • 69 citations
Action of 1,25-dihydroxyvitamin D3 on calcium balance and bone turnover and its effect on vertebral fracture rate
1990 • 68 citations
Determinants of Intact Parathyroid Hormone and Free 1,25-Dihydroxyvitamin D Levels in Mild and Moderate Renal Failure
1992 • 65 citations
Vitamin D and calcium transport
1991 • 65 citations
American Association of Clinical Endocrinologists 2001 Medical Guidelines for Clinical Practice for the Prevention and Management of Postmenopausal Osteoporosis.
2001 • 64 citations
Pernicious anaemia as a risk factor for osteoporosis
1992 • 64 citations
Low 1,25-Dihydroxyvitamin D, Secondary Hyperparathyroidism, and Normal Osteocalcinin Elderly Subjects
1986 • 64 citations
The Aetiology of Senile Osteoporosis: Secondary Hyperparathyroidism due to Renal Failure
1975 • 63 citations
Sunlight increases serum 25(OH) vitamin D concentration whereas 1,25(OH)2D3 is unaffected. Results from a general population study in Göteborg, Sweden (The WHO MONICA Project).
1995 • 63 citations
Pulsatile secretion of parathyroid hormone in normal young subjects: assessment by deconvolution analysis.
1993 • 62 citations
Role of Change in Vitamin D Metabolism with Age in Calcium and Phosphorus Metabolism in Normal Human Subjects*
1984 • 60 citations
In vivo intestinal absorption of calcium in humans.
1990 • 60 citations
Vitamin D deficiency and osteoporosis: the role of vitamin D deficiency and treatment with vitamin D and analogues in the prevention of osteoporosis‐related fractures
1996 • 60 citations
Inadequate status and impaired metabolism of vitamin D in the elderly.
1981 • 55 citations
Menopausal bone loss is partially regulated by dietary intake of vitamin D
1992 • 55 citations
Diminished effect of etidronate in vitamin D deficient osteopenic postmenopausal women
1996 • 53 citations
Role of estrogen deficiency in pathogenesis of secondary hyperparathyroidism and increased bone resorption in elderly women.
1997 • 51 citations
Regulation of calcium absorption by 1,25,dihydroxy-vitamin D—Studies of the effects of a bisphosphonate treatment
1982 • 51 citations
Production and Metabolic Clearance of 1,25-Dihydroxyvitamin D in Men: Effect of Advancing Age*
1990 • 50 citations
The Effects of the Menopause on Calcitriol and Parathyroid Hormone: Responses to a Low Dietary Calcium Stress Test*
1990 • 50 citations
The Mechanism of the Action of Growth Hormone on Vitamin D Metabolism in the Rat*
1981 • 49 citations
Effect of 25-hydroxy-vitamin D3 on intestinal absorption of calcium in normal man and patients with renal failure
1978 • 49 citations
Calcium absorption in the elderly
1975 • 48 citations
Effect of age on variables relating to calcium and phosphorus metabolism in women
1990 • 46 citations
Relations between calcidiol serum levels and bone mineral density in postmenopausal women with low bone density
1994 • 46 citations
Partial gastrectomy and mineral metabolism: effects on gastrin-calcitonin release
1990 • 42 citations
Effect of age on duodenal 1,25-dihydroxyvitamin D-3 receptors in Wistar rats
1990 • 41 citations
Bone mass is related to creatinine clearance in normal elderly women
1991 • 40 citations
Vitamin D, Nutritional Deficiency, and the Medical Paradigm
2003 • 40 citations
Age‐related changes in bone density, serum parathyroid hormone, calcium absorption and other indices of bone metabolism in Chinese women
1992 • 40 citations
The Calcium and Vitamin D Status in An Elderly Female Population and Their Response to Administered Supplemental Vitamin D3
1977 • 38 citations
Correlates of intestinal calcium absorption in women 10 years past the menopause
1993 • 37 citations
Intact parathyrin in postmenopausal women.
1988 • 36 citations
Influence of age on effects of endogenous 1,25-dihydroxyvitamin D on calcium absorption in normal women
1994 • 36 citations
Role of Estrogen Deficiency in Pathogenesis of Secondary Hyperparathyroidism and Increased Bone Resorption in Elderly Women
1997 • 33 citations
Pathophysiology of osteoporosis.
1992 • 28 citations
Competitive protein binding assay for 1,25-dihydroxyvitamin D in human plasma.
1978 • 27 citations
Serum levels of vitamin D metabolites in the elderly
1989 • 27 citations
Effect of age on renal responsiveness to parathyroid hormone and calcitonin in rats
1987 • 27 citations
The relationship of 1,25-dihydroxyvitamin D and radial bone mass
1990 • 27 citations
IGF-I Production by Mouse Osteoblasts
1990 • 27 citations
Clinical, biochemical and histological results of a double-blind trial with 1,25-dihydroxyvitamin D3, estradiol and placebo in post-menopausal osteoporosis.
1984 • 26 citations
Serum levels of 25-hydroxyvitamin D in postmenopausal osteoporosis
1981 • 25 citations
Effect of Age on Calcium Uptake in Isolated Duodenum Cells: Role of 1,25-Dihydroxyvitamin D3
1989 • 25 citations
Calcium and calcitriol therapy in osteoporotic postmenopausal women with impaired calcium absorption
1990 • 25 citations
Comparison of calcium effect on in vitro calcitonin and parathyroid hormone release by young and aged thyroparathyroid glands
1987 • 24 citations
Effects of vitamin D-binding protein on bone resorption stimulated by 1,25 dihydroxyvitamin D3
1990 • 24 citations
Seasonal Variation in 25-Hydroxyvitamin D and Parathyroid Hormone Concentrations in Healthy Elderly People
1994 • 24 citations
Multisite Immunochemiluminometric Assay for Simultaneously Measuring Whole-Molecule and Amino-Terminal Fragments of Human Parathyrin
1992 • 23 citations
Regulation of parathyroid hormone secretion by plasma calcium in aging rats
1991 • 22 citations
Set-point for parathyroid hormone release increases with postmaturational aging in the rat.
1992 • 22 citations
Effects of vitamin D and calcium on markers of bone metabolism in geriatric patients with low serum 25-hydroxyvitamin D levels
1991 • 21 citations
Effects of conjugated estrogen on the calcitriol response to parathyroid hormone in postmenopausal women.
1992 • 20 citations
Serum ionized calcium, as well as phosphorus and parathyroid hormone, is associated with the plasma 1,25-dihydroxyvitamin D3 concentration in normal postmenopausal women
1991 • 18 citations
The Effect of Aging on Intact PTH and Bone Density in Women
1992 • 17 citations
Kinetics of 1,25-dihydroxyvitamin D metabolism in the aging rat
1992 • 16 citations
Effects of conjugated estrogen on the calcitriol response to parathyroid hormone in postmenopausal women
1992 • 16 citations
Heterogeneous response to PTH in aging rats: evidence for skeletal PTH resistance
1991 • 15 citations
Changes in total body calcium following surgery for primary hyperparathyroidism
1986 • 15 citations
Vitamin D metabolism in osteoporotic women during treatment with estrogen, an anabolic steroid, or calcitonin
1990 • 14 citations
Reduced Serum Calcium and Inorganic Phosphate Levels in Normal Elderly Women
1986 • 13 citations
The effect of age on bone collagen turnover as assessed by pyridinium crosslinks and procollagen I C-terminal peptide
1993 • 10 citations
Evaluation of the degradation of desamino1,D-arginine8-vasopressin by nasal mucosa
1992 • 9 citations
Classification of dynamical diseases by new mathematical tools: Application of multi‐dimensional phase space analyses to the pulsatile secretion of parathyroid hormone
1992 • 9 citations
Biochemical Parameters of Vitamin D Nutriture in Old People in Jerusalem
1979 • 8 citations
Comparative effects of some hydroxylated vitamin D metabolites on parathyrin secretion by dispersed rat parathyroid cells in vitro
1982 • 4 citations