Treatment of Childhood-Onset Bipolar Disorder

A Rating Scale for Mania: Reliability, Validity and Sensitivity

1978 • 8,000 citations

Manic-Depressive Insanity and Paranoia.

1921 • 1,607 citations

Manic Depressive Insanity and Paranoia

1921 • 1,183 citations

Double-Blind and Placebo-Controlled Study of Lithium for Adolescent Bipolar Disorders With Secondary Substance Dependency

1998 • 519 citations

Practice Parameter for the Assessment and Treatment of Children and Adolescents With Bipolar Disorder

2006 • 477 citations

A Double-Blind, Randomized, Placebo-Controlled Study of Quetiapine as Adjunctive Treatment for Adolescent Mania

2002 • 400 citations

Effect Size of Lithium, Divalproex Sodium, and Carbamazepine in Children and Adolescents With Bipolar Disorder

2000 • 354 citations

Treatment Guidelines for Children and Adolescents With Bipolar Disorder

2006 • 350 citations

Pediatric Bipolar Disorder: A Review of the Past 10 Years

2005 • 347 citations

Olanzapine Versus Placebo in the Treatment of Adolescents With Bipolar Mania

2007 • 259 citations

Randomized, Placebo-Controlled Trial of Mixed Amphetamine Salts for Symptoms of Comorbid ADHD in Pediatric Bipolar Disorder After Mood Stabilization With Divalproex Sodium

2004 • 242 citations

A Prospective Open-Label Treatment Trial of Olanzapine Monotherapy in Children and Adolescents with Bipolar Disorder

2001 • 207 citations

Double-Blind 18-Month Trial of Lithium Versus Divalproex Maintenance Treatment in Pediatric Bipolar Disorder

2005 • 203 citations

A Double-Blind, Randomized, Placebo-Controlled Trial of Oxcarbazepine in the Treatment of Bipolar Disorder in Children and Adolescents

2006 • 197 citations

A Double-Blind Randomized Pilot Study Comparing Quetiapine and Divalproex for Adolescent Mania

2006 • 189 citations

Course and outcome of bipolar spectrum disorder in children and adolescents: A review of the existing literature

2006 • 165 citations

Risperidone for the treatment of acute mania in children and adolescents with bipolar disorder: a randomized, double‐blind, placebo‐controlled study

2009 • 155 citations

Combination Lithium and Divalproex Sodium in Pediatric Bipolarity

2003 • 155 citations

Open-Label, 8-Week Trial of Olanzapine and Risperidone for the Treatment of Bipolar Disorder in Preschool-Age Children

2005 • 151 citations

Omega-3 fatty acid monotherapy for pediatric bipolar disorder: A prospective open-label trial

2007 • 145 citations

An Open-Label Trial of Divalproex in Children and Adolescents With Bipolar Disorder

2002 • 144 citations

An Open-Label Study of Lamotrigine Adjunct or Monotherapy for the Treatment of Adolescents With Bipolar Depression

2006 • 139 citations

A Pilot Controlled Trial of Topiramate for Mania in Children and Adolescents With Bipolar Disorder

2005 • 138 citations

Combination pharmacotherapy in children and adolescents with bipolar disorder

2003 • 132 citations

Lithium Treatment of Acute Mania in Adolescents: A Large Open Trial

2003 • 124 citations

Open-label prospective trial of risperidone in combination with lithium or divalproex sodium in pediatric mania

2004 • 123 citations

A double‐blind, placebo‐controlled pilot study of quetiapine for depressed adolescents with bipolar disorder

2009 • 121 citations

Double-Blind, Placebo-Controlled Trial of Divalproex Monotherapy in the Treatment of Symptomatic Youth at High Risk for Developing Bipolar Disorder

2007 • 117 citations

A Double-Blind, Randomized, Placebo-Controlled Trial of Divalproex Extended-Release in the Treatment of Bipolar Disorder in Children and Adolescents

2009 • 117 citations

Open-Label Lithium for the Treatment of Adolescents With Bipolar Depression

2006 • 116 citations

Divalproex Monotherapy in the Treatment of Bipolar Offspring With Mood and Behavioral Disorders and at Least Mild Affective Symptoms

2003 • 114 citations

Lithium Treatment of Acute Mania in Adolescents: A Placebo-Controlled Discontinuation Study

2004 • 112 citations

Lithium for prepubertal depressed children with family history predictors of future bipolarity: a double-blind, placebo-controlled study

1998 • 110 citations

A 12-Week Single-Blind Trial of Quetiapine for the Treatment of Mood Symptoms in Adolescents at High Risk for Developing Bipolar I Disorder

2007 • 103 citations

Methylphenidate in the Treatment of Children and Adolescents With Bipolar Disorder and Attention-Deficit/Hyperactivity Disorder

2007 • 101 citations

Lithium in the Acute Treatment of Bipolar I Disorder: A Double-Blind, Placebo-Controlled Study

2015 • 101 citations

The Effectiveness and Tolerability of Aripiprazole for Pediatric Bipolar Disorders: A Retrospective Chart Review

2004 • 97 citations

Early symptoms of mania and the role of parental risk

2005 • 94 citations

Clozapine in Adolescent Inpatients with Acute Mania

2002 • 91 citations

Treatment of Early-Onset Schizophrenia Spectrum Disorders (TEOSS): Rationale, Design, and Methods

2007 • 90 citations

Randomized, placebo‐controlled trial of flax oil in pediatric bipolar disorder

2010 • 87 citations

Olanzapine/Fluoxetine Combination in Children and Adolescents With Bipolar I Depression: A Randomized, Double-Blind, Placebo-Controlled Trial

2014 • 86 citations

An Open-Label Trial of Risperidone in Children and Adolescents with Bipolar Disorder

2005 • 85 citations

Clozapine Treatment of Children and Adolescents with Bipolar Disorder and Schizophrenia: A Clinical Case Series

1995 • 80 citations

Update on Lithium Carbonate Therapy in Children and Adolescents

1994 • 79 citations

Aripiprazole in the Treatment of Pediatric Bipolar Disorder: A Systematic Chart Review

2005 • 75 citations

Efficacy and Safety of Quetiapine in Children and Adolescents With Mania Associated With Bipolar I Disorder

2013 • 72 citations

Aripiprazole for the treatment of pediatric bipolar I disorder: a 30‐week, randomized, placebo‐controlled study

2013 • 72 citations

Combination Lithium and Divalproex Sodium in Pediatric Bipolar Symptom Restabilization

2006 • 70 citations

Efficacy and Safety of Extended-Release Quetiapine Fumarate in Youth with Bipolar Depression: An 8 Week, Double-Blind, Placebo-Controlled Trial

2014 • 69 citations

Divalproex sodium for pediatric mixed mania: a 6‐month prospective trial

2005 • 67 citations

Asenapine for the Acute Treatment of Pediatric Manic or Mixed Episode of Bipolar I Disorder

2015 • 56 citations

Efficacy, Long-Term Safety, and Tolerability of Ziprasidone in Children and Adolescents with Bipolar Disorder

2013 • 55 citations

The Collaborative Lithium Trials (CoLT): specific aims, methods, and implementation

2008 • 49 citations

Dosing Strategies for Lithium Monotherapy in Children and Adolescents with Bipolar I Disorder

2011 • 47 citations

Quetiapine Adjunctive and Monotherapy for Pediatric Bipolar Disorder: A Retrospective Chart Review

2004 • 33 citations

The safety and effectiveness of open-label extended-release carbamazepine in the treatment of children and adolescents with bipolar I disorder suffering from a manic or mixed episode

2014 • 31 citations

Why do psychiatric drug research in children?

2003 • 25 citations

Ziprasidone Monotherapy in Pediatric Bipolar Disorder

2004 • 20 citations

A prospective open-label trial of paliperidone monotherapy for the treatment of bipolar spectrum disorders in children and adolescents

2013 • 19 citations

Long-term efficacy and safety of Aripiprazole in children (10-17 yo) with mania

2008 • 12 citations

Depressive episodes in children and adolescents with bipolar disorders

2002 • 5 citations

Are Girls and Boys From Different Planets?

2007 • 4 citations