Islet Changes in Human Diabetes

Classification and Diagnosis of Diabetes Mellitus and Other Categories of Glucose Intolerance

1979 • 4,730 citations

IMMUNOASSAY OF ENDOGENOUS PLASMA INSULIN IN MAN

1960 • 2,983 citations

ISLET-CELL ANTIBODIES IN DIABETES MELLITUS WITH AUTOIMMUNE POLYENDOCRINE DEFICIENCIES

1974 • 1,463 citations

Pathologic Anatomy of the Pancreas in Juvenile Diabetes Mellitus

1965 • 1,338 citations

Virus-Induced Diabetes Mellitus

1979 • 1,011 citations

Insulin Secretion in Response to Glycemic Stimulus: Relation of Delayed Initial Release to Carbohydrate intolerance in Mild Diabetes Mellitus*

1967 • 817 citations

Site-site interactions among insulin receptors. Characterization of the negative cooperativity.

1976 • 601 citations

Membrane receptors for hormones and neurotransmitters.

1976 • 573 citations

Common cytochemical and ultrastructural characteristics of cells producing polypeptide hormones (the APUD series) and their relevance to thyroid and ultimobranchial C cells and calcitonin

1968 • 566 citations

Diabetes mellitus nach Pankreasexstirpation

1890 • 464 citations

Studies on the pancreas of the guinea pig

1911 • 430 citations

The Spontaneously Diabetic Wistar Rat: Metabolic and Morphologic Studies

1977 • 409 citations

THE PLASMA INSULIN RESPONSE TO GLUCOSE INFUSION IN HEALTHY SUBJECTS AND IN DIABETES MELLITUS

1967 • 376 citations

Pancreatic polypeptide ? A postulated new hormone: Identification of its cellular storage site by light and electron microscopic immunocytochemistry

1976 • 371 citations

THE RELATION OE DIABETES MELLITUS TO LESIONS OF THE PANCREAS. HYALINE DEGENERATION OF THE ISLANDS OE LANGERHANS

1901 • 298 citations

The influence of amyloid deposits on the islet volume in maturity onset diabetes mellitus

1978 • 287 citations

Isolation and Characterization of Chicken Insulin

1968 • 278 citations

Hypertrophy and hyperplasia of somatostatin-containing D-cells in diabetes.

1976 • 248 citations

Quantitative Estimation of the Pancreatic Islet Tissue in Diabetic Subjects

1955 • 247 citations

The Banting Memorial Lecture 1975: Diabetes and the Alpha Cell

1976 • 233 citations

The islands of langerhans in 19 cases of obesity

1933 • 225 citations

Spontaneous Diabetes Mellitus: Reversal and Prevention in the BB/W Rat with Antiserum to Rat Lymphocytes

1979 • 212 citations

Chronic Calcifying Pancreatitis—Chronic Alcoholic Pancreatitis

1974 • 209 citations

Islet Cell Survival Determined by Morphology An Immunocytochemical Study of the Islets of Langerhans in Juvenile Diabetes Mellitus

1978 • 209 citations

Distribution and properties of glucagon immunoreactivity in the digestive tract of various mammals: An immunohistochemical and immunochemical study

1975 • 196 citations

Immunohistochemical localization of human pancreatic polypeptide (HPP) to a population of islet cells

1975 • 194 citations

Das Inselsystem des Pankreas

1953 • 186 citations

Pancreatic polypeptide and glucagon: Non-random distribution in pancreatic islets

1976 • 186 citations

Exocrine pancreatic function in juvenile-onset diabetes mellitus.

1976 • 181 citations

Antipancreatic Cellular Hypersensitivity in Diabetes Mellitus

1971 • 180 citations

Dietary Cyanide and Tropical Malnutrition Diabetes

1979 • 164 citations

The cytological characters of the areas of langerhans

1907 • 152 citations

Fine structure of islets of Langerhans in insular amyloidosis

1973 • 147 citations

The Structure and Metabolism of the Pancreatic Islets

1970 • 146 citations

The endocrine pancreas in chronic pancreatitis

1978 • 141 citations

A new type of granular cell in the islets of Langerhans of man

1931 • 136 citations

Isolation and preliminary characterization of 10-nm filaments from baby hamster kidney (BHK-21) cells.

1977 • 135 citations

Effect of age on glucose-stimulated insulin release by the beta-cell of the rat.

1979 • 135 citations

Zur normalen und pathologischen Morphologie der inneren Secretion der Bauchspeicheldrüse

1902 • 123 citations

Insulin-Dependent Diabetes: A Disease of Autoaggression

1976 • 120 citations

Observations on the Pancreatic Islet Tissue of Young Diabetic Subjects

1959 • 114 citations

The Pathology of Diabetes Mellitus

1967 • 109 citations

Possible Roles of the Pancreatic D-cell in the Normal and Diabetic States

1977 • 107 citations

Human C-peptide in normal and diabetic subjects

1975 • 104 citations

The Principles of Pathologic Histology.

1914 • 104 citations

Regional distribution and concentration of pancreatic polypeptide in the human and canine pancreas

1979 • 104 citations

Correlation of Beta-cell Granulation with Extractable Insulin of the Pancreas: Studies in Adult Human Diabetics and Nondiabetics

1955 • 99 citations

C-Peptide in children with juvenile diabetes

1976 • 89 citations

Hypothalamus, Pituitary and Aging

1976 • 88 citations

Infection of human pancreatic beta cell cultures with mumps virus

1978 • 87 citations

ISLETS OF LANGERHANS IN JUVENILE DIABETES MELLITUS

1973 • 84 citations

INFLUENCE OF THE MUTATION "DIABETES" ON INSULIN RELEASE AND ISLET MORPHOLOGY IN MICE OF DIFFERENT GENETIC BACKGROUNDS

1974 • 83 citations

Changes in the Islets of Langerhans in Cows Injected with Heterologous and Homologous Insulin

1966 • 78 citations

EVIDENCE FOR RAISED K-CELL LEVELS IN TYPE-I DIABETES

1979 • 75 citations

Spontaneous Diabetes in the Gnotobiotic BB/W Rat

1979 • 74 citations

Virus-induced Diabetes Mellitus: XI. Replication of Coxsackie B3 Virus in Human Pancreatic Beta Cell Cultures

1978 • 73 citations

D Cell, the Third Endocrine Element of the Pancreatic Islet

1968 • 73 citations

The ultrastructure of the human pancreatic islets

1971 • 71 citations

Spontaneous diabetes in dogs and cats

1967 • 69 citations

Localization of pancreatic polypeptide cells in a limited lobe of the human neonate pancreas: Remnant of the ventral primordium?

1979 • 68 citations

Histological and Autoradiographic Studies of the Islets of Mice Injected with Insulin Antibody

1966 • 66 citations

The Relation of Portal Cirrhosis to Hemochromatosis and to Diabetes Mellitus

1955 • 66 citations

Diabetes Mellitus Following Rodenticide Ingestion in Man

1978 • 65 citations

Congenital absence of islets of Langerhans.

1977 • 57 citations

Hyperplasia of “pancreatic polypeptide”-cells in the pancreas of juvenile diabetics

1977 • 56 citations

Aging and the Disposition of Glucose

1975 • 54 citations

Impaired Pancreatic Polypeptide Secretion in Chronic Pancreatitis*

1978 • 51 citations

Insulitis (Lymphocytic Infiltration of Pancreatic Islets) in Late-onset Diabetes

1972 • 51 citations

On the nature of the amyloid in human islets of langerhans

1974 • 47 citations

Diabetic Ketoacidosis: Evidence for C-Peptide and Proinsulin Secretion following Recovery

1972 • 46 citations

Diabetes Mellitus and Neuropathy Following Vacor Ingestion in Man

1979 • 45 citations

The Pathology of Diabetes Mellitus

1952 • 43 citations

Geriatric Endocrinology.

1978 • 41 citations

A possible role for insulin in the altered capability for hepatic enzyme adaptation during aging

1976 • 41 citations

A Specialized Membrane Junction between Nerve Endings and B‐Cells in Islets of Langerhans

1973 • 37 citations

Altered regulation of insulin secretion in isolated islets of different sizes in aging rats

1979 • 36 citations

Islet Pathology in Diabetes

1956 • 36 citations

Amyloid of human islets of Langerhans

1977 • 35 citations

Inflammation Involving the Islands of Langerhans in Diabetes

1928 • 31 citations

The Incidence and Significance of Degranulation of the Beta Cells In the Islets of Langerhans In Diabetes Mellitus

1953 • 29 citations

Studien über die pathologisch-anatomische Grundlage des Diabetes mellitus

1911 • 26 citations

Morphometric analysis of endocrine pancreas in old rats

1977 • 26 citations

The Aetiology of Diabetes Mellitus and its Complications

1965 • 25 citations

Pancreatic Exocrine Function in Maturity Onset Diabetes Mellitus

1973 • 25 citations

Insulitis in Cytomegalovirus Infection in a Newborn Infant

1973 • 24 citations

The Quantitative Variations of the Pancreatic Islet Tissue in a Mixed Series of Cases

1942 • 20 citations

Islet Cell Changes in the Rat Following Injection of Homogenized Islets

1974 • 19 citations

Organ culture of the islets of Langerhans from young and senescent rats

1980 • 19 citations

Elektronenmikroskopische Untersuchungen zur Inselregeneration im Rattenpankreas nach subtotaler Pankreatektomie

1970 • 19 citations

Inselneubildung im Pankreas bei Stenose des Ausführungsganges durch Pankreaskopfcarcinom

1936 • 18 citations

INTERNAL DISEASES, PEDIATRICS, NEUROLOGY, DIAGNOSTIC METHODS, ETC. NECROPSY FINDINS IN DIABETES

1926 • 17 citations

A METHOD FOR RAPID ESTIMATION OF THE ISLET VOLUME IN THE RAT PANCREAS BASED ON COUNTING INSTEAD OF MEASURING THE ISLET SECTION SURFACES

1959 • 10 citations

Generalized Islet Hypertrophy and Beta-Cell Hyperplasia in a Case of Long-Term Juvenile Diabetes

1972 • 10 citations

Das morphologische Bild der chronischen Pankreatitis

1966 • 10 citations

Three Cases of Acute Ketotic Diabetes Mellitus with Myocarditis: A Common Viral Origin?

1974 • 6 citations

Histochemical studies of the hyaline islets of diabetes

1954 • 6 citations

Pancreatic Perinuclear Inclusions in Diabetes Mellitus and Other Diseases

1977 • 6 citations

Evolution du coefficient d’assimilation de glucose avec l’ âge chez le rat

1971 • 5 citations

Hypoglycaemic coma: A presenting feature of secondary carcinoma of the liver

1977 • 3 citations

Selective Calcification of Pancreatic Islets of Langerhans: An Unusual Association with Hypercalcemia and Diabetes Mellitus

1978 • 2 citations