Effects of recombinant interleukin-2 administration on cytotoxic function following high-dose chemo-radiotherapy for hematological malignancy

Antileukemic Effect of Graft-versus-Host Disease in Human Recipients of Allogeneic-Marrow Grafts

1979 • 1,538 citations

Antileukemic Effect of Chronic Graft-versus-Host Disease

1981 • 1,112 citations

Bone Marrow Transplantation for Chronic Myelogenous Leukemia in Chronic Phase

1988 • 887 citations

Dissection of the lymphokine-activated killer phenomenon. Relative contribution of peripheral blood natural killer cells and T lymphocytes to cytolysis.

1986 • 698 citations

In vivo administration of purified human interleukin 2. II. Half life, immunologic effects, and expansion of peripheral lymphoid cells in vivo with recombinant IL 2.

1985 • 600 citations

The suppressive influences of human tumor necrosis factors on bone marrow hematopoietic progenitor cells from normal donors and patients with leukemia: synergism of tumor necrosis factor and interferon-gamma.

1986 • 492 citations

Eradication of disseminated murine leukemia by chemoimmunotherapy with cyclophosphamide and adoptively transferred immune syngeneic Lyt-1+2- lymphocytes.

1981 • 317 citations

Cytotoxicity of interleukin 2-activated lymphocytes for leukemia and lymphoma cells

1986 • 179 citations

Treatment of Acute Myelogenous Leukemia

1985 • 163 citations

Interleukin-2 induction of lymphokine-activated killer (LAK) activity in the peripheral blood and bone marrow of acute leukemia patients: II. Feasibility of LAK generation in children with active disease and in remission

1989 • 162 citations

Characterization of natural killer cells with antileukemia activity following allogeneic bone marrow transplantation

1986 • 148 citations

Influence of dose and duration of infusion of interleukin-2 on toxicity and immunomodulation.

1988 • 138 citations

Chemotherapy v marrow transplantation for adults with acute nonlymphocytic leukemia: a five-year follow-up

1988 • 137 citations

Comparison of allogeneic or autologous bone marrow transplantation and chemotherapy in patients with acute myeloid leukaemia in first remission: a prospective controlled trial

1989 • 127 citations

In vivo induction of gamma interferon and tumor necrosis factor by interleukin-2 infusion following intensive chemotherapy or autologous marrow transplantation

1989 • 122 citations

A phase I clinical trial of recombinant interleukin 2 following high dose chemo-radiotherapy for haematological malignancy: applicability to the elimination of minimal residual disease

1989 • 89 citations

Characterization of alloimmunization-induced T lymphocytes reactive against AKR leukemia in vitro and correlation with graft-vs-leukemia activity in vivo.

1983 • 83 citations

Inhibition of clonogenic growth of fresh leukemia cells by unstimulated and IL-2 stimulated NK cells of normal donors

1987 • 82 citations

In vivo induction of the lymphokine-activated killer phenomenon: interleukin 2-dependent human non-major histocompatibility complex-restricted cytotoxicity generated in vivo during administration of human recombinant interleukin 2.

1988 • 82 citations

In vivo effects of recombinant IL-2. I. Isolation of circulating Leu-19+ lymphokine-activated killer effector cells from cancer patients receiving recombinant IL-2.

1988 • 79 citations

Autologous bone marrow transplantation for acute leukaemia in remission

1986 • 77 citations

Natural killer cell activity in the rat. V. The circulation patterns and tissue localization of peripheral blood large granular lymphocytes (LGL).

1986 • 75 citations

Appearance and phenotypic characterization of circulating Leu 19+ cells in cancer patients receiving recombinant interleukin 2.

1988 • 49 citations

Cytotoxic effects of tumour necrosis factor and gamma-interferon on acute myeloid leukaemia blasts

1987 • 45 citations

Proliferation of human peripheral blood lymphocytes induced by recombinant human interleukin 2: Contribution of large granular lymphocytes and T lymphocytes

1986 • 43 citations

Cell-Mediated Toxicity of Interleukin-2-Activated Lymphocytes against Autologous and Allogeneic Human Myeloma Cells

1988 • 25 citations

Interleukin 2 enhances cytotoxic cell function in vitro after T‐cell depleted marrow transplantation

1987 • 25 citations

Spontaneous and interleukin 2 induced secretion of tumour necrosis factor and gamma interferon following autologous marrow transplantation or chemotherapy

1989 • 23 citations

Influence of T cells on the expression of lymphokine-activated killer cell activity and in vivo tissue distribution.

1988 • 22 citations

IL-2-induced polyclonal proliferation of human peripheral blood lymphocytes: functional and phenotypic characteristics of proliferating cells.

1989 • 9 citations