Phenotypic diversity of natural killer (NK) populations in patients with NK-type lymphoproliferative disease of granular lymphocytes

Identification of four subsets of human CD3-CD16+ natural killer (NK) cells by the expression of clonally distributed functional surface molecules: correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition.

1990 • 388 citations

CD3-negative lymphoproliferative disease of granular lymphocytes containing Epstein-Barr viral DNA.

1989 • 275 citations

A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function.

1990 • 254 citations

Involvement of HLA class I alleles in natural killer (NK) cell-specific functions: expression of HLA-Cw3 confers selective protection from lysis by alloreactive NK clones displaying a defined specificity (specificity 2).

1992 • 218 citations

Large Granular Lymphocyte Leukemia

1987 • 217 citations

Evidence of a natural killer (NK) cell repertoire for (allo) antigen recognition: definition of five distinct NK-determined allospecificities in humans.

1992 • 190 citations

The lymphoproliferative disease of granular lymphocytes. A heterogeneous disorder ranging from indolent to aggressive conditions

1987 • 184 citations

Clinical course and prognosis of the lymphoproliferative disease of granular lymphocytes. A multicenter study

1990 • 164 citations

Granular lymphocyte proliferative disorders: report of 12 cases and review of the literature.

1988 • 128 citations

Specific lysis of allogeneic cells after activation of CD3- lymphocytes in mixed lymphocyte culture.

1988 • 115 citations

Specific recognition of human CD3-CD16+ natural killer cells requires the expression of an autosomic recessive gene on target cells.

1990 • 92 citations

T cell receptor gene rearrangements define a monoclonal T cell proliferation in patients with T cell lymphocytosis and cytopenia

1986 • 79 citations

Rearrangement and expression of T-cell receptor genes in large granular lymphocyte leukemia

1988 • 77 citations

Acute transformation of chronic large granular lymphocyte leukemia associated with additional chromosome abnormality

1989 • 68 citations

T cell receptor (alpha, beta, gamma) gene rearrangements and expression in normal and leukemic large granular lymphocytes/natural killer cells

1987 • 66 citations

CD 16 surface molecules regulate the cytolytic function of CD3⁻CD16⁺ human natural killer cells

1989 • 53 citations

Chromosomal abnormalities define clonal proliferation in CD3‐ large granular lymphocyte leukemia

1990 • 51 citations

Pulmonary alveolar macrophages from patients with active sarcoidosis express type IV collagenolytic proteinase. An enzymatic mechanism for influx of mononuclear phagocytes at sites of disease activity.

1989 • 37 citations

Cell membrane expression and functional role of the p75 subunit of interleukin-2 receptor in lymphoproliferative disease of granular lymphocytes

1990 • 35 citations

Mechanisms accounting for the defective natural killer activity in patients with hairy cell leukemia

1990 • 33 citations

T cell receptor delta gene organization and expression in normal and leukemic natural killer cells.

1989 • 21 citations

The beta subunit of the interleukin-2 receptor mediates interleukin-2 induction of anti-CD3 redirected cytotoxic capability in large granular lymphocytes

1988 • 17 citations

Human natural killer cells: clonally distributed specific functions and triggering surface molecules.

1992 • 11 citations