PHARMACOGENETICS OF ALCOHOLISM

Nebraska Symposium on Motivation: 1955

1957 • 4,104 citations

Alcohol Problems in Adoptees Raised Apart From Alcoholic Biological Parents

1973 • 895 citations

Contributions to behavior-genetic analysis : the mouse as a prototype

1970 • 462 citations

Differences in Alcohol Preference among Inbred Strains of Mice

1959 • 453 citations

Genetic Selection for Voluntary Alcohol Consumption in the Albino Rat

1968 • 450 citations

Alkaloids from Catecholamines in Adrenal Tissue: Possible Role in Alcoholism

1970 • 441 citations

The subcellular distribution and properties of aldehyde dehydrogenases in rat liver

1973 • 409 citations

Ethnic Differences in Alcohol Sensitivity

1972 • 373 citations

Alcoholism

1970 • 313 citations

Ethanol and acetaldehyde metabolism in rat strains genetically selected for their ethanol preference

1973 • 229 citations

Genetic and environmental factors affecting ethanol metabolism in man

1971 • 207 citations

AN ATYPICAL HUMAN ALCOHOL DEHYDROGENASE

1965 • 191 citations

Alcohol Sensitivity and Ethnic Background

1974 • 190 citations

A comparison of the effects of alcohol on mice selectively bred for differences in ethanol sleep-time

1974 • 175 citations

Liver alcohol dehydrogenase in Japanese: high population frequency of atypical form and its possible role in alcohol sensitivity.

1975 • 173 citations

Brain Sensitivity to Alcohol in Inbred Mouse Strains

1966 • 162 citations

Vasomotor sensitivity to alcohol in diverse Mongoloid populations.

1973 • 157 citations

Genetic factors in alcohol preference of laboratory mice.

1961 • 144 citations

MICRODIFFERENTIATION IN A NATURAL POPULATION OF DROSOPHILA MELANOGASTER TO ALCOHOL IN THE ENVIRONMENT

1974 • 130 citations

Localization and characteristics of rat liver mitochondrial aldehyde dehydrogenases

1976 • 125 citations

Ethanol Metabolism in Various Racial Groups

1976 • 125 citations

Production of yeast alcohol dehydrogenase isoenzymes by selection

1976 • 116 citations

ATYPICAL HUMAN LIVER ALCOHOL DEHYDROGENASE

1968 • 116 citations

Alcohol Aversion in the Rat: Behavioral Assessment of Noxious Drug Effects

1970 • 115 citations

Alcohol Metabolism in American Indians and Whites

1976 • 114 citations

Alcohol and alcoholism

1971 • 113 citations

Inheritance of Drinking Behavior: A Study on Intelligence, Personality, and Use of Alcohol of Adult Twins.

1967 • 112 citations

Experimentally Induced Changes in the Free Selection of Ethanol

1960 • 109 citations

A Study in Alcoholism: Clinical, Social-Psychiatric and Genetic Investigations

1951 • 107 citations

Measurement of alcohol preference in genetic experiments.

1964 • 101 citations

Oxidation of Acetaldehyde by Rat‐Liver Mitochondria in Relation to Ethanol Oxidation and the Transport of Reducing Equivalents across the Mitochondrial Membrane

1973 • 101 citations

Alcohol preference as a function of its caloric utility in mice.

1963 • 99 citations

Enzyme activities and ethanol preference in mice

1968 • 98 citations

Genetic Influence upon Phenobarbital-induced Increase in Rat Liver Supernatant Aldehyde Dehydrogenase Activity

1972 • 96 citations

Liver aldehyde and alcohol dehydrogenase activities in rat strains genetically selected for their ethanol preference

1975 • 95 citations

Inherited Differences in Intensity of Alcohol Withdrawal Reactions in Mice

1973 • 95 citations

Effects of para-chlorophenylalanine and 5-hydroxytryptophan on alcohol intake in the rat

1973 • 93 citations

Induction of different rat liver supernatant aldehyde dehydrogenases by phenobarbital and tetrachlorodibenzo-p-dioxin.

1977 • 92 citations

Ethanol metabolism in subiects possessing typical and atypical liver alcohol dehydrogenase

1967 • 84 citations

Ethanol preference in the rat: interactions between brain serotonin and ethanol, acetaldehyde, paraldehyde, 5-HTPand 5-HTOL

1972 • 83 citations

Role of cytosolic rat liver aldehyde dehydrogenase in the oxidation of acetaldehyde during ethanol metabolism in vivo

1975 • 79 citations

Organic Solvents as Probes for the Structure and Function of the Bacterial Membrane: Effects of Ethanol on the Wild Type and an Ethanol-Resistant Mutant of Escherichia coli K-12

1973 • 76 citations

GENETICS OF RESISTANCE TO ENVIRONMENTAL STRESSES IN DROSOPHILA POPULATIONS

1973 • 75 citations

Rat strains specially selected for their voluntary alcohol consumption.

1971 • 75 citations

ATYPICAL HUMAN LIVER ALCOHOL DEHYDROGENASE

1968 • 73 citations

Sensitivity to low doses of ethanol and pentobarbital in mice selected for sensitivity to hypnotic doses of ethanol.

1976 • 72 citations

Differences between the sexes in voluntary alcohol consumption and liver ADH-activity in inbred strains of mice

1968 • 72 citations

Effects of Tetraethylthiuramdisulfide (Antabuse) on the Metabolism and Consumption of Ethanol in Mice

1966 • 70 citations

Ethanol-induced mouse strain differences in locomotor activity

1975 • 69 citations

5-Hydroxytryptamine and 5-hydroxyindolylacetic acid content in brain of rat strains selected for their alcohol intake

1972 • 68 citations

Psychopharmacogenetics

1975 • 64 citations

Association and linkage between alcoholism and eleven serological markers.

1975 • 62 citations

Involvement of biogenic amine metabolism in ethanol addiction.

1975 • 62 citations

Dopamine and Noradrenaline Content in the Brain of Rat Strains Selected for their Alcohol Intake

1975 • 60 citations

Intraventricular injection of 5-hydroxytryptamine and alcohol consumption in rats.

1974 • 59 citations

Induction of Liver Acetaldehyde Dehydrogenase: Possible Role in Ethanol Tolerance after Exposure to Barbiturates

1971 • 56 citations

Biochemical genetics of bacterial sporulation

1973 • 53 citations

Alcohol withdrawal reactions in mouse strains selectively bred for long or short sleep times

1975 • 51 citations

Heritability of Alcohol Preference in Laboratory Mice and Rats

1970 • 48 citations

Factors involved in ethanol narcosis: Analysis in mice of three inbred strains

1973 • 48 citations

The effect of pargyline and other monoamine oxidase inhibitors on blood acetaldehyde levels in ethanol-intoxicated mice.

1976 • 47 citations

Biological Sciences: Sex Difference in Acetaldehyde Exhalation following Ethanol Administration in C57BL Mice

1972 • 44 citations

MECHANISMS THAT UNDERLIE SEX‐LINKED AND GENOTYPICALLY DETERMINED DIFFERENCES IN THE DEPRESSANT ACTIONS OF ALCOHOL*

1976 • 42 citations

Influence of Thyroid Function on the Acetaldehyde Level of Blood and Liver of Intact Rats during Ethanol Metabolism

1969 • 41 citations

Social Modification of Alcohol Consumption in Inbred Mice

1975 • 39 citations

Ethanol sleep times and hepatic alcohol and aldehyde dehydrogenase activities in mice

1972 • 37 citations

Biochemical aspects of alcoholism

1976 • 35 citations

Salsolinol differentially affects mice selected for sensitivity to alcohol

1976 • 35 citations

Subcellular site of acetaldehyde oxidation in rat liver

1976 • 35 citations

Ethanol self-selection in rats: A distinction between absolute and 95 per cent ethanol

1970 • 34 citations

Acetaldehyde levels during ethanol oxidation: A diet-induced change and its relation to liver aldehyde dehydrogenases and redox states

1975 • 33 citations

GENETICS AS A TOOL IN ALCOHOL RESEARCH

1972 • 33 citations

Ethanol Preference in Strains of Rats Selectively Bred for Behavioral Characteristics

1969 • 32 citations

Metabolism of Ethanol and Alcoholism: Racial and Acquired Factors

1972 • 30 citations

Selection of high ethanol-yieldingSaccharomyces

1971 • 30 citations

The effect of p-chloroamphetamine on the consumption of ethanol by rats.

1970 • 29 citations

GENETIC AND BIOCHEMICAL CORRELATES OF ALCOHOL PREFERENCE IN MICE

1966 • 29 citations

Alcohol selection by DBA and C57BL mice arising from ova transfers

1975 • 28 citations

Adh n5: A temperature-sensitive mutant at the Adh locus in Drosophila

1974 • 27 citations

Effects of alcohol on acquisition and retention of passive-avoidance conditioning in different mouse strains.

1973 • 26 citations

Use of genetic to test the potential role of serotonin in alcohol preference

1975 • 25 citations

Inhibiting action of n-butyraldoxime on ethanol metabolism and on natural ethanol preference of C57BL mice.

1970 • 22 citations

Sex and strain as factors in voluntary alcohol intake

1973 • 21 citations

Selection and Avoidance of Alcohol Solutions by Two Strains of Inbred Mice and Derived Generations

1969 • 21 citations

The estimation of heritability for the self-selection of alcohol in the albino rat.

1969 • 20 citations

Reduction of alcohol selection by pargyline in mice

1976 • 16 citations

Alcohol and amine catabolism in fungus Aspergillus nidulans

1972 • 12 citations

A Study in Alcoholism: Clinical, Social-Psychiatric and Genetic Investigations.

1952 • 10 citations

EVIDENCE OF GENETIC FACTORS IN THE APPETITE FOR ALCOHOL AND ALCOHOLISM

1972 • 10 citations

Aldehyde dehydrogenase inducibility and ethanol preference in rats.

1975 • 9 citations

INDUCTION11We have referred to “induction” of aldehyde dehydrogenase throughout this paper to signify an increase in enzyme activity. Although we have some evidence from immunological studies that there is a corresponding increase in enzyme protein, these studies are not yet complete. OF CYTOSOLIC ALDEHYDE DEHYDROGENASE ISOZYMES: INFLUENCE ON ACETALDEHYDE METABOLISM

1977 • 3 citations

Deleted Work

1955 • 0 citations