REPAIR OF cis-PLATINUM (II) DIAMMINE DICHLORIDE-INDUCED DNA DAMAGE AND CELL SENSITIVITY

The Mechanism of Action of Antitumor Platinum Compounds

1979 • 408 citations

Isolation of deoxyribonucleic acid from mammalian tissues

1967 • 192 citations

The Repair of DNA Modified by Cytotoxic, Mutagenic, and Carcinogenic Chemicals

1978 • 173 citations

Mitotically Synchronized Mammalian Cells: A Simple Method for Obtaining Large Populations

1964 • 171 citations

Quantitative aspects of the repair of alkylated DNA in cultured mammalian cells

1971 • 143 citations

Effect of cis -Platinum(II)Diamminodichloride on Wild Type and Deoxyribonucleic Acid Repair-Deficient Mutants of Escherichia coli

1973 • 137 citations

Increased sensitivity of UV-repair-deficient human cells to DNA bound platinum products which unlike thymine dimers are not recognized by an endonuclease extracted from Micrococcus luteus

1978 • 131 citations

The effect of cis-diamminedichloroplatinum (II) on cultured human lymphoma cells and its therapeutic implications.

1973 • 120 citations

Kinetics of formation and disappearance of a DNA cross-linking effect in mouse leukemia L1210 cells treated with cis- and trans-diamminedichloroplatinum(II).

1978 • 115 citations

Excision repair of cis-diamminedichloroplatinum(II)-induced damage to DNA of Chinese hamster cells.

1979 • 90 citations

Excision repair of DNA base damage in human cells treated with the chemical carcinogen 4-nitroquinoline 1-oxide

1977 • 81 citations

Removal of bound carcinogen during DNA repair in nondividing human lymphocytes.

1972 • 77 citations

Excision of 7-bromomethylbenz[a]anthracene-DNA adducts in replicating mammalian cells

1977 • 52 citations

DNA repair after mustard gas alkylation by sensitive and resistant Yoshida sarcoma cells in vitro

1970 • 51 citations

The effect of cis-dichlorodiammineplatinum(II) on Escherichia coli B the role of fil, exr and hcr markers

1973 • 42 citations

Effects of cis-platinum(II) diamminedichloride on survival and the rate of DNA synthesis in synchronously growing Chinese hamster V79-379A cells in the absence and presence of caffeine inhibited post-replication repair; Evidence for an inducible repair mechanism

1978 • 39 citations

G1 phase chinese hamster V79-379A cells are inherently more sensitive to platinum bound to their dna than mid S phase or asynchronously treated cells

1979 • 34 citations

Investigations into the mechanisn of action of antitumour platinum compounds: Time- and dose-dependent changes in the alkaline sucrose gradient sedimentation profiles of DNA from hamster cells treated with cis-platinum(II) diamminedichloride

1975 • 29 citations

Effects of cis-platinum(II) diamminedichloride on survival and the rate of DNA synthesis in synchronously growing HeLa cells in the absence and presence of caffeine

1978 • 27 citations

Repair processes and the response of dividing and non-dividing cells to methyl methanesulphonate and dimethyl sulphate

1976 • 19 citations

Caffeine inhibits excision of 7-bromomethylbenz (a) anthracene-DNA adducts from exponentially growing but not from stationary phase Chinese hamster cells

1978 • 12 citations