PREDICTION OF PROTEIN CONFORMATION

Principles of Polymer Chemistry.

1954 • 16,197 citations

Conformation of Polypeptides and Proteins

1968 • 2,929 citations

Theory of the Phase Transition between Helix and Random Coil in Polypeptide Chains

1959 • 1,756 citations

Structure of Myoglobin: A Three-Dimensional Fourier Synthesis at 2 Å. Resolution

1960 • 1,313 citations

Structure of Hæmoglobin: A Three-Dimensional Fourier Synthesis at 5.5-Å. Resolution, Obtained by X-Ray Analysis

1960 • 1,270 citations

Use of Helical Wheels to Represent the Structures of Proteins and to Identify Segments with Helical Potential

1967 • 1,178 citations

Nonenzymatic Cleavage of Peptide Bonds: The Methionine Residues in Bovine Pancreatic Ribonuclease

1962 • 929 citations

The disulphide bonds of insulin

1955 • 904 citations

Chain reversals in proteins

1973 • 652 citations

Tertiary Structure of Ribonuclease

1967 • 573 citations

The Sequence of Amino Acid Residues in Bovine Pancreatic Ribonuclease: Revisions and Confirmations

1963 • 562 citations

A possible three-dimensional structure of bovine α-lactalbumin based on that of hen's egg-white lysozyme

1969 • 517 citations

The Three-Dimensional Structure of Ribonuclease-S

1970 • 510 citations

The Sequence of the Amino Acid Residues in Performic Acid-oxidized Ribonuclease

1960 • 428 citations

The Nature of the Amino Acid Residues Involved in the Inactivation of Ribonuclease by Iodoacetate

1959 • 409 citations

Calculations of Conformations of Polypeptides

1968 • 387 citations

Folding of Polypeptide Chains in Proteins: A Proposed Mechanism for Folding

1971 • 309 citations

Comparison of the Amino Acid Sequence of Bovine α-Lactalbumin and Hens Egg White Lysozyme

1967 • 308 citations

The Disulfide Bonds of Ribonuclease

1960 • 255 citations

Analysis of Conformations of Amino Acid Residues and Prediction of Backbone Topography in Proteins

1974 • 236 citations

Computation of structures of homologous proteins. .alpha.-Lactalbumin from lysozyme

1974 • 230 citations

Theoretical and experimental studies of conformations of polypeptides

1971 • 219 citations

Minimization of polypeptide energy. I. Preliminary structures of bovine pancreatic ribonuclease S-peptide.

1967 • 200 citations

Protein folding

1972 • 178 citations

The Influence of Amino Acid Sequence on Protein Structure

1965 • 161 citations

Theoretical determination of sterically allowed conformations of a polypeptide chain by a computer method

1965 • 159 citations

Consistent force field for calculation of vibrational spectra and conformations of some amides and lactam rings

1970 • 157 citations

Energy Parameters in Polypeptides. VI. Conformational Energy Analysis of the N‐Acetyl N′‐Methyl Amides of the Twenty Naturally Occurring Amino Acids

1973 • 148 citations

On the Sequence of Residues 11 to 18 in Bovine Pancreatic Ribonuclease

1962 • 143 citations

The histidine residue in the active centre of ribonuclease

1959 • 125 citations

Correlation between the distribution of amino acids and alpha helices

1966 • 121 citations

The Reactivities of the Histidine Residues at the Active Site of Ribonuclease toward Halo Acids of Different Structures

1965 • 113 citations

A Reinvestigation of the Sequence of Residues 11 to 18 in Bovine Pancreatic Ribonuclease

1962 • 113 citations

Helix Probability Profiles of Denatured Proteins and Their Correlation with Native Structures

1970 • 109 citations

New Perspectives in Biology

1964 • 106 citations

Kinetic Investigation of the α‐Chymotrypsin‐Catalyzed Hydrolysis of Peptide Substrates

1973 • 93 citations

Statistical analysis of the correlation among amino acid residues in helical, β-stractural and non-regular regions of globular proteins

1971 • 83 citations

Minimization of polypeptide energy

1971 • 83 citations

Predictions of structural homologies in cytochrome c proteins

1971 • 81 citations

The influence of short-range interactions on protein conformation. I. Side chain-backbone interactions within a single peptide unit.

1968 • 79 citations

Analysis of the Code Relating Sequence to Secondary Structure in Proteins

1970 • 78 citations

On the Alkylation of Amino Acid Residues at the Active Site of Ribonuclease

1966 • 75 citations

Helix-Coil Stability Constants for the Naturally Occurring Amino Acids in Water. II. Characterization of the Host Polymers and Application of the Host-Guest Technique to Random Poly(hydroxypropylglutamine-co-hydroxybutylglutamine)

1971 • 74 citations

Helix-Coil Stability Constants for the Naturally Occurring Amino Acids in Water. IV. Alanine Parameters from Random Poly(hydroxypropylglutamine-co-L-alanine)

1972 • 74 citations

Role of Medium-Range Interactions in Proteins

1973 • 65 citations

Molecular Theory of the Helix–Coil Transition in Polyamino Acids. III. Evaluation and Analysis of s and σ for Polyglycine and Poly-<scp>l</scp>-alanine in Water

1971 • 58 citations

Helix-Coil Stability Constants for the Naturally Occurring Amino Acids in Water. III. Glycine Parameters from Random Poly(hydroxybutylglutamine-co-glycine)

1971 • 56 citations

Helix-Coil Stability Constants for the Naturally Occurring Amino Acids in Water. VI. Leucine Parameters from Random Poly(hydroxypropylglutamine-co-L-leucine) and Poly(hydroxybutylglutamine-co-L-leucine)

1972 • 54 citations

Helix-Coil Stability Constants for the Naturally Occuring Amino Acids in Water. X. Tyrosine Parameters from Random Poly(hydroxypropylglutamine-co-L-tyrosine)

1976 • 52 citations

Refinement of the x-ray structure of lysozyme by complete energy minimization

1974 • 52 citations

Helix-Coil Stability Constants for the Naturally Occurring Amino Acids in Water. I. Properties of Copolymers and Approximate Theories

1971 • 51 citations

Minimization of polypeptide energy

1971 • 47 citations

A study of the correlation between the amino acid composition and the helical content of proteins

1966 • 46 citations

Helix-Coil Stability for the Naturally Occurring Amino Acids in Water. VIII. Valine Parameters from Random Poly(hydroxypropylglutamine-co-L-valine) and Poly(hydroxybutylglutamine-co-L-valine)

1973 • 46 citations

CONFORMATIONAL ENERGY CALCULATIONS OF ENZYME‐SUBSTRATE INTERACTIONS. II. Computation of the Binding Energy for Substrates in the Active Site of α‐Chymotrypsin

1972 • 43 citations

MINIMIZATION OF POLYPEPTIDE ENERGY, VIII. APPLICATION OF THE DEFLATION TECHNIQUE TO A DIPEPTIDE

1969 • 42 citations

Prediction of structural homology between bovine α-lactalbumin and hen egg white lysozyme

1971 • 42 citations

Helix-Coil Stability Constants for the Naturally Occurring Amino Acids in Water. 15. Arginine Parameters from Random Poly(hydroxybutylglutamine-co-L-arginine)

1977 • 34 citations

Helix-Coil Stability Constants for the Naturally Occurring Amino Acids in Water. V. Serine Parameters from Random Poly(hydroxybutylglutamine-co-L-serine)

1972 • 33 citations

A Model for the Helix-Coil Transition in Specific-Sequence Copolymers of Amino Acids

1971 • 32 citations

Helix-Coil Stability Constants for the Naturally Occurring Amino in Water. VII Phenylalanine Parameters from Random Poly(hydroxypropylglutamine-co-L-L-phenylalanine)

1973 • 29 citations

THE INFLUENCE OF SHORT-RANGE INTERACTIONS ON PROTEIN CONFORMATION, III. DIPEPTIDE DISTRIBUTIONS IN PROTEINS OF KNOWN SEQUENCE AND STRUCTURE

1969 • 24 citations

REFINEMENT OF THE MOLECULAR STRUCTURE OF ACTINOMYCIN D BY ENERGY MINIMIZATION

1973 • 22 citations

Refinement of X ray data on proteins. II. Adjustment of structure of specified geometry to relieve atomic overlaps

1973 • 20 citations

MINIMIZATION OF POLYPEPTIDE ENERGY, VII. SECOND DERIVATIVES AND STATISTICAL WEIGHTS OF ENERGY MINIMA FOR DECA-L-ALANINE

1969 • 20 citations

Refinement of X-ray data on proteins. I. Adjustment of atomic coordinates to conform to a specified geometry

1972 • 19 citations

Hairpin bend and interhelical interactions in α-helical poly(l-alanine) in water

1972 • 17 citations

Structural studies of pancreatic ribonuclease.

1967 • 15 citations

Calculation of the Conformation of the Pentapeptide cyclo(Glycylglycylglycylprolyprolyl). III. Treatment of a Flexible Molecule

1973 • 15 citations

Minimization of polypeptide energy. IX. A procedure for seeking the global minimum of functions with many minima

1970 • 10 citations

Minimization of polypeptide energy XII. The methods of partial energies and cubic subdivision

1973 • 9 citations

Calculation of the Conformation of the Pentapeptide cyclo(Glycylglycylglycylprolylprolyl). III. Treatment of a Flexible Molecule

1973 • 5 citations

ChemInform Abstract: INTERMOLECULAR POTENTIALS FROM CRYSTAL DATA PART 3, DETERMINATION OF EMPIRICAL POTENTIALS AND APPLICATION TO THE PACKING CONFIGURATIONS OF HYDROCARBONS, CARBOXYLIC ACIDS, AMINES, AMIDES AND AMINO ACIDS

1974 • 1 citations