Specific peptide-protein interactions in the ribonuclease S' system studied by 13C nuclear magnetic resonance spectroscopy with selectively 13C-enriched peptides.

Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides

1970 • 3,443 citations

The Preparation of Subtilisin-modified Ribonuclease and the Separation of the Peptide and Protein Components

1959 • 632 citations

Solid Phase Peptide Synthesis

1970 • 544 citations

The Preparation of Merrifield‐Resins Through Total Esterification With Cesium Salts

1973 • 512 citations

Theory of Nuclear Overhauser Enhancement and C13–1H Dipolar Relaxation in Proton-Decoupled Carbon-13 NMR Spectra of Macromolecules

1972 • 450 citations

Spectrophotometric assay of bovine pancreatic ribonuclease by the use of cytidine 2′:3′-phosphate

1960 • 405 citations

Verbesserte Synthese von tert.‐Butyloxycarbonyl‐aminosäuren durch pH‐Stat‐Reaktion

1967 • 383 citations

Helix-coil transition of the isolated amino terminus of ribonuclease

1971 • 310 citations

The Synthesis of Ribonuclease A

1971 • 293 citations

DIALYSIS STUDIES. III. MODIFICATION OF PORE SIZE AND SHAPE IN CELLOPHANE MEMBRANES

1961 • 158 citations

Hormonal Interactions at the Molecular Level

1973 • 105 citations

NMR‐Studies on the Structure of the Active Site of Pancreatic Ribonuclease A

1969 • 95 citations

Nuclear magnetic resonance studies of sperm whale myoglobin specifically enriched with 13C in the methionine methyl groups.

1976 • 88 citations

Conformational Studies of Pancreatic Ribonuclease and Its Subtilisin-produced Derivatives

1965 • 80 citations

Studies on the Synthesis of Histidine Peptides. I.N^im-Tosylhistidine Derivatives as Starting Materials

1974 • 74 citations

Concentration-dependent hydrogen exchange kinetics of 3H-labeled S-peptide in ribonuclease S

1976 • 74 citations

Reconstitution of Fully Active RNase S by Carboxypeptidase-degraded RNase S-Peptide

1963 • 63 citations

The Action of Trypsin on Ribonuclease-S^*

1962 • 62 citations

Preparation and Studies of 19F-Labeled and Enriched 13C-Labeled Semisynthetic Ribonuclease-s' Analogues

1973 • 62 citations

Covalent structural analysis of yeast inorganic pyrophosphatase.

1978 • 60 citations

Correlation proton magnetic resonance studies at 250 MHz of bovine pancreatic ribonuclease. II. The pH and inhibitor-induced conformational transitions affecting histidine-48 and one tyrosine residue of ribonuclease A

1975 • 56 citations

Synthesis of a Pentekontapeptide with High Lipolytic Activity Corresponding to the Carboxyl-Terminal Fifty Amino Acids of Ovine β-Lipotropin

1974 • 53 citations

Synthesis, Purification, and Properties of a Semisynthetic Ribonuclease S Incorporating 4-Fluoro-l-histidine at Position 12

1974 • 51 citations

S-peptide-S-protein system. Model for hormone-receptor interaction

1973 • 50 citations

Nuclear Magnetic Resonance Titration Curves of Histidine Ring Protons

1973 • 49 citations

Mechanism of dissociation of S-peptide from ribonuclease S

1977 • 48 citations

SOLID PHASE SYNTHESIS OF A 42-RESIDUE FRAGMENT OF STAPHYLOCOCCAL NUCLEASE: PROPERTIES OF A SEMISYNTHETIC ENZYME

1969 • 43 citations

Use of fluorine-19 nuclear magnetic resonance to study conformation changes in selectively modified ribonuclease S

1971 • 40 citations

CARBON-13 NUCLEAR MAGNETIC RESONANCE STUDIES OF PROTEINS

1977 • 38 citations

Novel high-yield synthesis of .gamma. esters of glutamic acid and .beta. esters of aspartic acid by the copper-catalyzed hydrolysis of their diesters

1975 • 38 citations

Nuclear magnetic resonance titration curves of histidine ring protons. A direct assignment of the resonances of the active site histidine residues of ribonuclease.

1976 • 37 citations

Interactions of oxytocin with bovine neurophysins I and II. Use of carbon-13 nuclear magnetic resonance and hormones specifically enriched with carbon-13 in the glycinamide-9 and half-cystine-1 positions

1977 • 34 citations

Studies of individual carbon sites of hen egg white lysozyme by natural abundance carbon 13 nuclear magnetic resonance spectroscopy. Assignment of the nonprotonated aromatic carbon resonances to specific residues in the sequence.

1977 • 33 citations

Spectrophotometric Titration of the Imidazole Groups of Bovine Pancreatic Ribonuclease^*

1965 • 33 citations

Nuclear magnetic resonance titration curves of histidine ring protons. Conformational transition affecting three of the histidine residues of ribonuclease.

1975 • 32 citations

Direct observation of the methionine residues of cytochrome c by 13C nuclear magnetic resonance spectroscopy.

1978 • 32 citations

Interaction of S-protein with S-peptide and with synthetic S-peptide analogs. Spectroscopic and calorimetric investigation

1972 • 29 citations

Helix-coil transition of a synthetic polypeptide monitored by Fourier transform carbon-13 nuclear magnetic resonance

1972 • 29 citations

Studies of individual carboxyl groups in proteins by carbon 13 nuclear magnetic resonance spectroscopy.

1978 • 27 citations

Fourier Transform N.M.R. Spectroscopy

1977 • 27 citations

Investigation of Nucleotide · Ribonuclease‐A Complexes with High‐Resolution ³¹P‐Nuclear‐Magnetic‐Resonance Spectroscopy

1973 • 27 citations

Relation between Structure and Function in Some Partially Synthetic Ribonucleases S′

1975 • 26 citations

Ribonuclease S-peptide. A model for molecular recognition.

1976 • 25 citations

Microenvironment of histidine 12 in ribonuclease-S as detected by carbon-13 nuclear magnetic resonance

1974 • 24 citations

pH-dependence of 13C chemical shifts and 13C,H coupling constants in imidazole and L-histidine.

1975 • 23 citations

Nuclear magnetic resonance titration curves of histidine ring protons. Ribonuclease S-peptide and S-proteins.

1976 • 23 citations

Carbon 13 as a Probe of Helix Formation in Semisynthetic Ribonuclease-s'

1974 • 22 citations

Proton nuclear magnetic resonance studies of the association of ribonuclease S-peptide and analogs with ribonuclease S-protein

1972 • 22 citations

The influence of amino acid side-chains on α-helix stability: S-peptide analogues and related ribonucleases S′

1976 • 22 citations

Further evidence for an allosteric model for ribonuclease

1976 • 22 citations

13-C nuclear magnetic resonance studies of the binding of selectively ¹³C -enriched oxytocins to the neurohypophyseal protein, bovine neurophysin II

1977 • 19 citations

Studies on polypeptides. XXXVII. Competitive inhibition in the S-peptide-S-protein system

1967 • 16 citations

Selectively enriched carbon-13-labeled proline-7 and carbon-13-labeled leucine-8 ocytocins as probes for the analysis of peptide hormone interactions with bovine neurophysin I using carbon-13 nuclear magnetic resonance spectroscopy

1977 • 15 citations

AN IMPROVED SYNTHESIS OF tert‐ BUTYLOXYCARBONYL‐L‐HISTIDINE

1976 • 14 citations

Solid phase peptide synthesis. Effect of trifluoroacetic acid concentration on the removal of the tert-butyloxycarbonyl protecting group

1976 • 10 citations

Spectrophotometric measurement of binding of S-peptide analogs to S-protein

1972 • 9 citations

Synthesis and enzymatic activity of an RNase S′ analogue in which the 4‐imidazolylglycyl residue takes the position and the role of histidine‐12

1976 • 8 citations

Near-ultraviolet difference absorption and circular dichroism studies on partially synthetic ribonucleases S′

1976 • 7 citations