Effects and Proposed Mechanisms of Action of Lindane in Mammals: Unsolved Problems

3H-baclofen and 3H-GABA bind to bicuculline-insensitive GABAB sites in rat brain

1981 • 1,044 citations

DRUG INTERACTIONS AT THE GABA RECEPTOR-IONOPHORE COMPLEX

1982 • 696 citations

Kindling

1978 • 482 citations

Patterns of activation in a monosynaptic cortical pathway: The perforant path input to the dentate area of the hippocampal formation

1971 • 473 citations

Confirmation from choline acetylase analyses of a massive cholinergic innervation to the rat hippocampus

1967 • 469 citations

Further study of the role of calcium in synaptic transmission

1970 • 461 citations

Opioid modulation of appetite

1983 • 452 citations

Entorhinal Activation of Dentate Granule Cells

1966 • 442 citations

Septal neurons containing glutamic acid decarboxylase immunoreactivity project to the hippocampal region in the rat brain

1984 • 438 citations

Localization of transmitter candidates in the brain: the hippocampal formation as a model

1977 • 416 citations

Eating and Its Disorders.

1984 • 404 citations

Physiological identification and analysis of dentate granule cell responses to stimulation of the medial and lateral perforant pathways in the rat

1977 • 283 citations

Interactions of lindane, toxaphene and cyclodienes with brain-specific -butylbicyclophosphorothionate receptor

1984 • 203 citations

Hippocampal long-term potentiation: Mechanisms and implications for memory.

1982 • 195 citations

Long-term potentiation in the hippocampus

1983 • 167 citations

Calcium in long-term potentiation as a model for memory

1983 • 164 citations

Evidence for similarities between cyclodiene type insecticides and picrotoxinin in their action mechanisms

1983 • 153 citations

High-affinity stereospecific binding of cyclodiene insecticides and γ-hexachlorocyclohexane to γ-aminobutyric acid receptors of rat brain

1985 • 139 citations

Cellular and molecular neurotoxicology

1985 • 131 citations

Gamma Benzene Hexachloride Toxicity

1977 • 130 citations

Effects of Insecticides on Excitable Tissues

1972 • 119 citations

Mode of action of lindane, dieldrin and related insecticides in the central nervous system.

1982 • 106 citations

Difference in the picrotoxinin receptor between the cyclodiene-resistant and susceptible strains of the german cockroach

1983 • 94 citations

Septal modulation of the population spike in the fascia dentata produced by perforant path stimulation in the rat

1982 • 92 citations

Polysynaptic activation of the dentate gyrus of the hippocampal formation: An olfactory input via the lateral entorhinal cortex

1978 • 83 citations

Inhibition of gamma-aminobutyric acid (GABA)-induced chloride uptake by gamma-BHC and heptachlor epoxide

1982 • 80 citations

Barbiturate recognition site on the GABA/benzodiazepine receptor complex is distinct from the picrotoxinin/TBPS recognition site

1984 • 80 citations

The effects of cholinesterase inhibitors on the body temperature of the rat

1968 • 71 citations

Lindane : monograph of an insecticide

1972 • 69 citations

Mechanisms of actions of neurotoxic substances

1982 • 68 citations

Pharmacological evidence for a discrete neurotoxic action of dieldrin (HEOD) in the American cockroach, Periplaneta americana (L.)

1973 • 67 citations

The neurotoxic action of dieldrin and its derivatives in the cockroach

1971 • 65 citations

Effects of lindane-type insecticides in mammals: unsolved problems.

1985 • 63 citations

Biochemical pharmacology of the gamma-aminobutyric acid receptor/ionophore protein.

1984 • 59 citations

Role of neurotransmitters in seizure mechanisms in the kindling model of epilepsy.

1984 • 56 citations

DDT and Related Chlorinated Hydrocarbon Insecticides: Pharmacological Basis of Their Toxicity in Mammals

1975 • 50 citations

The pharmacokinetics of HEOD (dieldrin) in the rat

1969 • 46 citations

Comparative Response of Insects and Mammals to Certain Halogenated Hydrocarbons Used as Insecticides

1955 • 44 citations

Neuropharmacological effects of isomers of hexachlorocyclohexane

1981 • 44 citations

Gamma-Benzene Hexachloride Toxicity

1975 • 42 citations

Mechanisms of neurotoxic action of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) in immature and adult rats.

1970 • 42 citations

Dieldrin-induced alterations in biogenic amine content of rat brain

1978 • 41 citations

The role of the cholinergic systems in the central control of thermoregulation in rats

1979 • 37 citations

Interactions of pyrethroid and cyclodiene insecticides with nicotinic acetylcholine and GABA receptors.

1985 • 35 citations

Dieldrin poisoning in man.

1957 • 35 citations

Solubilization and Detergent Effects on Interactions of Some Drugs and Insecticides with the t‐Butylbicyclophosphorothionate Binding Site Within the γ‐Aminobutyric Acid Receptor‐Ionophore Complex

1985 • 34 citations

The gamma isomer of hexachlorocyclohexane in the treatment of scabies.

1948 • 33 citations

Proconvulsant effects of lindane: enhancement of amygdaloid kindling in the rat.

1982 • 32 citations

The toxicity of dieldrin to man: report on a survey.

1959 • 31 citations

The action of lindane in accelerating the spontaneous release of transmitter at the frog neuromuscular junction

1979 • 30 citations

Dieldrin Poisoning in Man

1957 • 30 citations

The kindled seizure: production of and modification by dieldrin in rats.

1980 • 26 citations

Monosodium glutamate exposure in the neonate alters hypothalamic and pituitary neuropeptide levels in the adult

1981 • 25 citations

Secretory hyperactivity and mitochondrial changes in neurosecretory cells of an insect

1977 • 25 citations

Time course of the effects of trimethyltin on limbic evoked potentials and distribution of tin in blood and brain in the rat.

1984 • 24 citations

Olfactory connections of substantia innominata and nucleus of the horizontal limb of the diagonal band in the rat: An electrophysiological study

1982 • 22 citations

Systems and interactions: an approach to the pharmacology of eating and hunger.

1984 • 22 citations

The effects of neurotoxicants on kindling and kindled seizures*1

1985 • 22 citations

Effects of nereistoxin on the neuroexcitatory action of insecticides

1975 • 21 citations

Proconvulsant actions of lindane: effects on afterdischarge thresholds and durations during amygdaloid kindling in rats.

1983 • 21 citations

Epidemic outbreak of neuro-ocular manifestations due to chronic BHC poisoning.

1977 • 21 citations

Convulsions Induced by Lindane and the Involvement of the GABAergic System

1983 • 20 citations

The Gamma Isomer of Hexachlorocyclohexane in the Treatment of Scabies11Studies, observations and reports from the Dermatological Departments of the Barnard Free Skin and Cancer Hospital and the School of Medicine, Washington University, St. Louis, Missouri, Service of Richard S. Weiss, M.D.

1948 • 19 citations

Convulsive action of small single oral doses of the insecticide lindane

1976 • 18 citations

Comparison of the neurotoxic effects of chlordecone and dieldrin in the rat.

1982 • 16 citations

Convulsions in weanling rabbits after a single topical application of 1% lindane

1976 • 15 citations

Role of noradrenaline, 5-hydroxytryptamine and acetylcholine in the hypothermic and convulsive effects of α-chlordane in rats

1974 • 14 citations

The persistence of kindled amygdaloid seizures in rats exposed to lindane.

1983 • 13 citations

Chlordecone (Kepone) exposure in the neonate selectively alters brain and pituitary endorphin levels in prepuberal and adult rats.

1982 • 13 citations

Cellular and molecular toxicology

2009 • 11 citations

APPRAISAL OF THE TOXICITY OF THE GAMMA ISOMER OF HEXACHLOROCYCLOHEXANE IN CLINICAL USAGE

1950 • 10 citations

γ-Hexachlorocyclohexane inhibition of the calcium fluxes at the desensitized mouse neuromuscular junction

1984 • 8 citations

Studies on 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT)-induced hyperthermia: effects of cold exposure and aminopyrine injections.

1973 • 7 citations

Subchronic dietary exposure of rats to chlordecone (Kepone) modifies levels of hypothalamic beta-endorphin.

1982 • 7 citations

Deep temporal lobe projections to the nucleus of the diagonal band of Broca

1976 • 4 citations

Dieldrin induced changes in hippocampal evoked potentials in the rat.

1980 • 2 citations

Amygdaloid kindling progressively increases posttetanic potentiation and long-term potentiation of responses evoked in the hippocampus and dentate gyrus.

1982 • 1 citations