Minireview: The Brain Renin Angiotensin System 1982

Intra- and extrahypothalamic vasopressin and oxytocin pathways in the rat

1978 • 1,022 citations

THE PREPARATION AND FUNCTION OF THE HYPERTENSIN-CONVERTING ENZYME

1956 • 994 citations

High-affinity enkephalin-degrading peptidase in brain is increased after morphine

1978 • 652 citations

Angiotensin I converting enzyme.

1975 • 566 citations

Comptes rendus de l'Academie bulgare des Sciences

2010 • 437 citations

Evidence for a Central Mechanism in Angiotensin Induced Hypertension.

1961 • 383 citations

ANGIOTENSIN AND RENIN IN RAT AND DOG BRAIN

1971 • 352 citations

Angiotensin-Forming Enzyme in Brain Tissue

1971 • 315 citations

Distribution of angiotensin II receptors in rat brain

1977 • 303 citations

Renin in dog brain

1971 • 301 citations

DISTRIBUTION AND PROPERTIES OF ANGIOTENSIN CONVERTING ENZYME OF RAT BRAIN

1972 • 298 citations

Hypertension: Physiopathology and Treatment

1984 • 282 citations

Angiotensin II Stimulation of Prostaglandin Production in Cultured Human Vascular Endothelium

1975 • 278 citations

Subfornical Organ Efferents to Neural Systems for Control of Body Water

1979 • 248 citations

Angiotensin in the Brain

1978 • 247 citations

A central effect of angiotensin: release of pituitary pressor material.

1970 • 231 citations

Hydrolysis of enkephalin by cultured human endothelial cells and by purified peptidyl dipeptidase

1978 • 203 citations

Enkephalin effects on blood pressure, heart rate, and baroreceptor reflex.

1980 • 199 citations

Two distinct enkephalinases: Solubilization, partial purification and separation from angiotensin converting enzyme

1979 • 189 citations

Iontophoresis and transmitter mechanisms in the mammalian central nervous system

1978 • 176 citations

Radioautographic localization of specific binding sites for blood-borne angiotensin II in the rat brain

1980 • 176 citations

Central Actions of Angiotensin and Related Hormones

1977 • 174 citations

Evidence for an endogenous brain renin-angiotensin system.

1979 • 174 citations

Angiotensin stimulation of the central nervous system

2005 • 170 citations

Purification and Characterisation of a Membrane-Bound Substance-P-Degrading Enzyme from Human Brain

1981 • 170 citations

The brain renin-angiotensin system: A model for the synthesis of peptides in the brain

1978 • 163 citations

Immunochemical identification of renin in rat brain and distinction from acid proteases

1978 • 145 citations

Regional study of cerebral ventricle sensitive sites to angiotensin II

1976 • 134 citations

Components of the Renin-Angiotensin System in the Cerebrospinal Fluid of Rats and Dogs with Special Consideration of the Origin and the Fate of Angiotensin II

1980 • 128 citations

Horseradish peroxidase study in rat of the neural connections of the organum vasculosum of the lamina terminalis

1981 • 127 citations

Primary structure of porcine pepsin. III. Amino acid sequence of a cyanogen bromide fragment, CB2A, and the complete structure of porcine pepsin.

1975 • 124 citations

Ventricular Obstruction: Effect on Drinking Induced by Intracranial Injection of Angiotensin

1975 • 123 citations

Subfornical Organ Lesions Reduce the Pressor Effect of Systemic Angiotensin II

1980 • 122 citations

Angiotensin Injected into the Neostriatum After Learning Disrupts Retention Performance

1977 • 121 citations

Frontiers in Neuroendocrinology

1978 • 118 citations

Specific angiotensin II receptive neurons in the cat subfornical organ

1976 • 116 citations

Enkephalinase activity in rat peripheral organs

1981 • 116 citations

Is there a brain renin-angiotensin system?

1977 • 114 citations

Angiotensin-induced thirst: Effects of third ventricle obstruction and periventricular ablation

1978 • 114 citations

Immunocytochemical Localization of Angiotensin II and Vasopressin in Rat Hypothalamus: Evidence for Production in the Same Neuron

1980 • 108 citations

Growth and differentiated properties of a kidney epithelial cell line (MDCK)

1981 • 104 citations

Localization of Renin in Trophoblasts in Human Chorion Laeve at Term Pregnancy*

1981 • 104 citations

Renin and prorenin in hog brain: Ubiquitous distribution and high concentration in the pituitary and pineal

1980 • 102 citations

Renin-like immunocytochemical activity in the rat and mouse brain

1980 • 100 citations

A Radioimmunoassay for the Direct Measurement of Renin in Mice and Its Application to Submaxillary Gland and Kidney Studies

1974 • 98 citations

Pseudorenin: A NEW ANGIOTENSIN-FORMING ENZYME

1969 • 93 citations

Immunohistochemical localization of renin in luteinizing hormone-producing cells of rat pituitary.

1981 • 91 citations

Is ‘enkephalinase” identical with ‘angiotensin-converting enzyme’?

1979 • 91 citations

Visualization of Specific Angiotensin II Binding Sites in the Brain by Fluorescent Microscopy

1980 • 87 citations

Co-identity of brain angiotensin converting enzyme with a membrane bound dipeptidyl carboxypeptidase inactivating Met-enkephalin

1979 • 82 citations

The central and peripheral effects of Captopril (SQ 14225) on the arterial pressure of the spontaneously hypertensive rat

1980 • 79 citations

The Effects of Intracerebroventricular Administration of Renin on Drinking and Blood Pressure¹

1975 • 79 citations

Wide distribution of immunoreactive renin in nerve cells of human brain.

1980 • 78 citations

Angiotensin Regulates Release and Synthesis of Serotonin in Brain

1978 • 77 citations

Purification and partial characterization of rat brain acid proteinase (isorenin)

1978 • 77 citations

Huntington's chorea: Selective depletion of activity of angiotensin converting enzyme in the corpus striatum

1977 • 74 citations

Regional distribution of angiotensinogen in rat brain

1978 • 73 citations

Converting-enzyme in the choroid plexus, brain, and kidney: Immunocytochemical and biochemical studies in rats

1981 • 73 citations

Angiotensin II-sensitive neurons in septal areas of the rat

1980 • 72 citations

The area postrema plays no role in the pressor action of angiotensin in the rat

1980 • 72 citations

‘Enkephalinase’ is distinct from brain ‘angiostensin-converting enzyme’

1979 • 69 citations

Angiotensin-converting enzyme: Presence of high activity in choroid plexus of mammalian brain

1978 • 68 citations

Effects of angiotensin II on central neurons

1973 • 64 citations

Angiotensin II responsive cells in the organum vasculosum lamina terminalis (OVLT) recorded in hypothalamic brain slices

1980 • 63 citations

Elevation of Substance P‐like Immunoreactivity in Rat Central Nervous System by Protease Inhibitors

1980 • 62 citations

Endogenous brain angiotensin II disrupts passive avoidance behavior in rats

1979 • 61 citations

A Renin-like Activity in Pineal Gland and Hypophysis

1975 • 60 citations

Inhibition of in situ metabolism of [3H](met5)-enkephalin and potentiation of (met5)-enkephalin analgesia by captopril

1980 • 58 citations

Fluorimetrie Determination of Dipeptidyl Carboxypeptidase

1975 • 53 citations

Renin in Rat and Mouse Brain: Immunohistochemical Identification and Localization

1980 • 52 citations

Separation of drinking and pressor responses to central angiotensin by monoamines

1981 • 52 citations

Bradykinin, Kallidin and Kallikrein

1979 • 51 citations

Immunocytochemical localization of renin in the submandibular gland of the mouse.

1978 • 51 citations

Interrelations between vasopressin and the renin-angiotensin system.

1979 • 51 citations

Separation of dog brain renin-like activity from acid protease activity.

1979 • 50 citations

Substance P degradation by rat brain peptidases: Inhibition bY SQ 20881

1979 • 50 citations

SUBCELLULAR LOCALIZATION AND PARTIAL PURIFICATION OF A CHLORIDE DEPENDENT ANGIOTENSIN‐I CONVERTING ENZYME FROM RAT BRAIN

1978 • 48 citations

Inactivation of substance P and its C-terminal fragments in rat plasma and its inhibition by Captopril

1981 • 47 citations

Adrenal Regulation of Regional Brain Angiotensinogen Content*

1980 • 47 citations

The Distribution of Angiotensinogen in Dog Brain Studied by Cell Fractionation*

1978 • 47 citations

Specific antibody to hog renal renin and its application to the direct radioimmunoassay of renin in various organs.

1979 • 46 citations

Angiotensin-converting enzyme activity in isolated brain microvessels

1979 • 46 citations

Characterization of the active site of mouse submaxillary gland renin

1980 • 46 citations

Immunohistochemical localization of renin in mouse brain

1980 • 45 citations

Studies on angiotensinogen of plasma and cerebrospinal fluid in normal and hypertensive human subjects.

1980 • 44 citations

Opiate regulation of angiotensin-induced drinking and vasopressin release.

1981 • 43 citations

Evidence for a Functional, Independent Brain-Angiotensin System: Correlation Between Regional Distribution of Brain Angiotensin Receptors, Brain Angiotensinogen and Drinking During the Estrous Cycle of Rats

1982 • 41 citations

The brain renin-angiotensin system: a critical analysis.

1979 • 41 citations

Hormonal Influences on Motivation, Learning, and Memory Processes

1976 • 40 citations

Separation of human brain angiotensin-converting enzyme from enkephalin-degrading activity

1979 • 40 citations

Inhibitory effects of luteinizing hormone releasing hormone (LH-RH) on neurons in the organum vasculosum lamina terminalis (OVLT)

1979 • 39 citations

Chronic Hypoxia in Rats: Alterations of Striato‐nigral Angiotensin Converting Enzyme, GABA and Glutamic Acid Decarboxylase

1980 • 38 citations

SENSITIVE SITES IN THE BRAIN FOR THE BLOOD PRESSURE AND DRINKING RESPONSES TO ANGIOTENSIN II

1977 • 37 citations

Role of kinins and substance p in the central blood pressure regulation of normotensive and spontaneously hypertensive rats

1981 • 36 citations

The effect of acute administration of an angiotensin converting enzyme inhibitor, captopril (SQ 14,225), on experimentally induced thirsts in rats.

1980 • 35 citations

INTERACTIONS AND PROPERTIES OF SOME COMPONENTS OF THE RENIN–ANGIOTENSIN SYSTEM IN BRAIN

1977 • 35 citations

Properties of angiotensin-converting enzyme in intact cerebral microvessels.

1981 • 35 citations

Release of angiotensinogen by rat brain in vitro

1980 • 35 citations

Definite Evidence for the Presence of [Ile5]-Angiotensin I and [Ile5]-Angiotensin II in the Brain of Rats

1982 • 34 citations

Regional changes in rat brain angiotensinogen following bilateral nephrectomy.

1982 • 34 citations

Characterization of a distinct membrane bound dipeptidyl carboxypeptidase inactivating enkephalin in brain

1980 • 33 citations

Antidipsogenic role of the E-prostaglandins.

1978 • 31 citations

An angiotensin-like peptide in the brain

1980 • 31 citations

<b>Renin in anterior pituitary, pineal, and neuronal cells of mouse brain. immunohistochemical </b><b>localization </b>

1980 • 31 citations

A distinct peptidyl dipeptidase that degrades enkephalin: Exceptionally high activity in rabbit kidney

1981 • 28 citations

Definitive Evidence for Renin in Rat Brain by Affinity Chromatographic Separation from Protease

1978 • 28 citations

Evidence for differential localization of angiotensin‐l converting enzyme and renin in the corpus striatum of rat

1980 • 27 citations

Totally inactive renin zymogen and different forms of active renin in hog brain tissues.

1981 • 27 citations

In vivo activity of purified mouse brain renin

1981 • 27 citations

RENIN SUBSTRATE IN THE CNS: POTENTIAL SIGNIFICANCE TO CENTRAL REGULATORY MECHANISMS

1977 • 22 citations

Inhibition of angiotensin converting enzyme by substance P

1979 • 21 citations

Inhibition of the partially purified canine lung angiotensin I converting enzyme by opioid peptides

1980 • 18 citations

An Intrinsic Renin-Angiotensin System in the Brain

1972 • 17 citations

Angiotensin and CNS Regulation of Blood Pressure

1980 • 16 citations

Difference in behaviour between synthetic and endogenous substance P in human plasma

1979 • 16 citations

Dissociation between in vivo and in vitro measurements of converting enzyme activity after chronic oral treatment with captopril in rats

1982 • 16 citations

Regulation of Angiotensinogen in Cerebrospinal Fluid and Plasma

1982 • 11 citations

A renin-like activity in the human hypophysis.

1977 • 11 citations

Pituitary Renin: Purification and Characterization

1982 • 8 citations

A Comparison of Human Renin Substrate in Plasma and Cerebrospinal Fluid

1982 • 7 citations

In vivo enzyme activity of purified human brain renin

1978 • 6 citations

Renin activity in the prehypertensive and early hypertensive stage of spontaneously hypertensive rats.

1976 • 3 citations