THE RECEPTOR FOR EGF FUNCTIONS AS A TYROSINE-SPECIFIC PROTEIN KINASE

Epidermal Growth Factor

1979 • 2,964 citations

Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes.

1980 • 1,184 citations

New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues.

1981 • 925 citations

Epidermal growth factor-receptor-protein kinase interactions. Co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity.

1980 • 853 citations

A native 170,000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles.

1982 • 788 citations

Stimulation of tyrosine-specific phosphorylation by platelet-derived growth factor

1982 • 675 citations

Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells

1981 • 669 citations

Rapid enhancement of protein phosphorylation in A-431 cell membrane preparations by epidermal growth factor.

1979 • 530 citations

Molecular mechanism of mitogen action: Processing of receptor induced by epidermal growth factor

1978 • 271 citations

Affinity labeling of the protein kinase associated with the epidermal growth factor receptor in membrane vesicles from A431 cells.

1982 • 232 citations

Human transforming growth factor. Production by a melanoma cell line, purification, and initial characterization.

1982 • 223 citations

Monoclonal antibodies against receptor for epidermal growth factor induce early and delayed effects of epidermal growth factor.

1981 • 191 citations

Epidermal growth factor stimulates the phosphorylation of synthetic tyrosine-containing peptides by A431 cell membranes.

1982 • 166 citations

Epidermal Growth Factor-Urogastrone, a Polypeptide Acquiring Hormonal Status

1980 • 156 citations

Characterization by electrophoresis of epidermal growth factor stimulated phosphorylation using A-431 membranes

1980 • 153 citations

Thrombin and epidermal growth factor become linked to cell surface receptors during mitogenic stimulation

1979 • 140 citations

Purified EGF receptor–kinase interacts specifically with antibodies to Rous sarcoma virus transforming protein

1981 • 130 citations

Direct linkage of epidermal growth factor to its receptor

1979 • 113 citations

Similarities and differences between the effects of epidermal growth factor and Rous sarcoma virus.

1981 • 108 citations

Alteration of epidermal growth factor-dependent phosphorylation during rat liver regeneration.

1982 • 96 citations

Altered epidermal growth factor (EGF)-stimulated protein kinase activity in variant A431 cells with altered growth responses to EGF

1982 • 95 citations

Direct linkage of 125I-EGF to cell surface receptors. A useful artifact of chloramine-T treatment.

1982 • 89 citations

Isolation of the human placenta receptor for epidermal growth factor-urogastrone

1979 • 80 citations

Anti-pp60src antibodies are substrates for EGF-stimulated protein kinase

1981 • 78 citations

Rapid and specific enhancement of phosphorylation of two normal rat kidney cell membrane polypeptides of Mr = 170,000 and 150,000 by epidermal growth factor in vitro.

1981 • 44 citations

Epidermal growth factor: relationship between receptor down regulation in cultured NRK cells and epidermal growth factor enhancement of phosphorylation of a 170,000 molecular weight membrane protein in vitro

1981 • 24 citations

Epidermal growth factor-stimulated phosphorylation of tyrosine residues on a 120 000 dalton protein in mouse liver plasma membrane subfractions

1981 • 16 citations

Range of Molluscs

1967 • 1 citations