CHEMICAL DECOMPOSITION OF CHLOROETHYLNITROSOUREAS

Experimental evaluation of potential anticancer agents VIII. Effects of certain nitrosoureas on intracerebral L1210 leukemia.

1963 • 369 citations

Interstrand cross-linking of DNA by 1,3-bis(2-chloroethyl)-1-nitrosourea and other 1-(2-haloethyl)-1-nitrosoureas.

1977 • 297 citations

The Modes of Decomposition of 1,3-Bis(2-chloroethyl)-1-nitrosourea and Related Compounds

1967 • 177 citations

The Antitumor Agent, 1,3-bis(2-chloroethyl)-1-nitrosourea

1966 • 106 citations

A chemical basis for the antitumor activity of chloroethylnitrosoureas

1976 • 90 citations

2-chloroethanol formation as evidence for a 2-chloroethyl alkylating intermediate during chemical degradation of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea and 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea.

1975 • 71 citations

Decomposition of N-(2-chloroethyl)-N-nitrosoureas in aqueous media

1975 • 64 citations

Chemistry of nitrosoureas. Decomposition of deuterated 1,3-bis(2-chloroethyl)-1-nitrosourea

1976 • 45 citations

Decomposition of BCNU (1,3-Bis(2-chloroethyl)-1-nitrosourea) in aqueous solution

1974 • 45 citations

Potential Anticancer Agents--XXXL. The Relationship of Analogues of 1-Methyl-3-nitro-1-nitrosoguanidine (NSC-9369)

1960 • 44 citations

Reaction of BCNU (1,3-Bis (2-chloroethyl)-1-nitrosourea) with polycytidylic acid. Substitution of the cytosine ring

1974 • 43 citations

Some effects of 1, 3-bis(2-chloroethyl)-1-nitrosourea upon the synthesis of protein and nucleic acids in vivo and in vitro.

1965 • 40 citations

Chemistry of nitrosoureas. Intermediacy of 4,5-dihydro-1,2,3-oxadiazole in 1,3-bis(2-chloroethyl)-1-nitrosourea decomposition

1980 • 35 citations

Comparison of mutagenicity, antitumor activity, and chemical properties of selected nitrosoureas and nitrosoamides.

1979 • 24 citations

Chemistry of nitrosoureas. Decomposition of 1,3-bis(threo-3-chloro-2-butyl)-1-nitrosourea and 1,3-bis(erythro-3-chloro-2-butyl)-1-nitrosourea

1977 • 7 citations