Insulin-like peptides stimulate metabolism but not proliferation of human fibroblasts

The serial cultivation of human diploid cell strains

1961 • 7,886 citations

The limited in vitro lifetime of human diploid cell strains

1965 • 5,595 citations

Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype.

1970 • 1,002 citations

Dual control of cell growth by somatomedins and platelet-derived growth factor.

1979 • 926 citations

“Pleiotypic Response”

1971 • 415 citations

Insulin and epidermal growth factor. Human fibroblast receptors related to deoxyribonucleic acid synthesis and amino acid uptake.

1975 • 367 citations

Factors involved in the modulation of cell proliferation in vivo and in vitro: The role of fibroblast and epidermal growth factors in the proliferative response of mammalian cells

1978 • 360 citations

Nature of Insulin Action on Amino Acid Uptake by the Isolated Diaphragm

1962 • 321 citations

Polypeptides with nonsuppressible insulin-like and cell-growth promoting activities in human serum: isolation, chemical characterization, and some biological properties of forms I and II.

1976 • 319 citations

The Somatomedins: A Family of Insulinlike Hormones under Growth Hormone Control

1974 • 281 citations

Permeation of Glucose by Simple and Facilitated Diffusion by Novikoff Rat Hepatoma Cells in Suspension Culture and Its Relationship to Glucose Metabolism

1972 • 215 citations

Hormonal growth control of cells in culture

1978 • 199 citations

The Inhibition of Sugar Transport in Chick Embryo Fibroblasts by Cytochalasin B

1973 • 196 citations

Genealogies of clones of diploid fibroblasts

1974 • 165 citations

DNA Synthesis in Human Fibroblasts: Stimulation by Insulin and by Nonsuppressible Insulin-like Activity (NSILA-S)

1974 • 122 citations

Insulin receptors in normal and transformed fibroblasts: relationship to growth and transformation

1976 • 117 citations

Fibroblasts as an Experimental Tool in Metabolic and Hormone Studies

1973 • 114 citations

Nonsuppressible insulin-like activity and thyroid hormones: major pituitary-dependent sulfation factors for chick embryo cartilage.

1976 • 109 citations

Non-suppressible insulin-like activity of human serum

1966 • 103 citations

Identification of two somatomedin a active polypeptides and in vivo effects of a somatomedin a concentrate

1974 • 82 citations

Assay and partial purification of factors from serum that control multiplication of human diploid fibroblasts

1978 • 78 citations

Sugar Transport in Chick Embryo Fibroblasts

1974 • 77 citations

Effect of Insulin on the Conversion of Glucose-C-14 to C-14-02 by Normal and Diabetic Fibroblasts in Culture

1969 • 63 citations

Effects of partially purified preparations with nonsuppressible insulin-like activity (NSILA-S) on sulfate incorporation into rat and chicken cartilage

1973 • 59 citations

Partial Purification, Characterization, and Assay of a Slightly Acidic Insulin-Like Peptide (ILAs) from Human Plasma*

1978 • 53 citations

Properties of two growth-stimulating proteins isolated from fetal calf serum

1973 • 48 citations

Stimulation of hexose transport in cultured human skin fibroblasts by insulin

1979 • 44 citations

Contribution of Human Somatomedin Activity to the Serum Growth Requirement of Human Skin Fibroblasts and Chick Embryo Fibroblasts in Culture*

1978 • 42 citations

In vitro studies of age-associated diseases.

1979 • 39 citations

Antagonistic effects of insulin and cortisol on coordinate control of metabolism and growth in cultured fibroblasts

1977 • 38 citations

Insulin-Stimulated Glucose Uptake by Subcellular Particles from Adipose Tissue Cells

1970 • 37 citations

Expression of androgen-responsive properties in human skin fibroblast strains of genital and nongenital origin

1977 • 33 citations

Nonsuppressible Insulin-Like Activity (NSILA).II. Regulation of Serum Concentrations by Growth Hormone and Insulin*

1978 • 31 citations

Isolation of a Somatomedin From Plasma of Rats Bearing Growth Hormone Secreting Tumors*

1977 • 27 citations

Insulin Action in Isolated Rat Thymocytes

1972 • 24 citations

Insulin and somatomedins A and B: Comparison of biological activities in cultured human skin-derived fibroblasts

1977 • 20 citations