Heparin enhances angiogenesis by a systemic mode of action.

Endothelial cell-derived basic fibroblast growth factor: synthesis and deposition into subendothelial extracellular matrix.

1987 • 1,045 citations

Cultured endothelial cells produce heparinlike inhibitor of smooth muscle cell growth

1981 • 685 citations

Basic fibroblast growth factor binds to subendothelial extracellular matrix and is released by heparitinase and heparin-like molecules

1989 • 597 citations

Inhibition of rat arterial smooth muscle cell proliferation by heparin. II. In vitro studies.

1980 • 337 citations

Control of Angiogenesis with Synthetic Heparin Substitutes

1989 • 292 citations

Effect of controlled adventitial heparin delivery on smooth muscle cell proliferation following endothelial injury.

1990 • 256 citations

Structural determinants of the capacity of heparin to inhibit the proliferation of vascular smooth muscle cells

1984 • 189 citations

Specific binding of basic fibroblast growth factor to basement membrane‐like structures and to purified heparan sulfate proteoglycan of the EHS tumor

1988 • 172 citations

Heparin protects heparin-binding growth factor-I from proteolytic inactivation in vitro

1988 • 149 citations

ANGIOGENESIS FACTOR FROM HUMAN MYOCARDIAL INFARCTS

1983 • 102 citations

Improvement of treadmill capacity and collateral circulation as a result of exercise with heparin pretreatment in patients with effort angina.

1988 • 95 citations

Heparin degradation in the endothelial cells

1987 • 88 citations

Heparin‐derived oligosaccharides: Affinity for acidic fibroblast growth factor and effect on its growth‐promoting activity for human endothelial cells

1989 • 62 citations

Inhibition of intimal hyperplasia after arterial injury by heparins and heparinoid

1988 • 44 citations

Do ischemic hearts stimulate endothelial cell growth?

1984 • 26 citations

Protamine and mast-cell-mediated angiogenesis in the rat.

1990 • 15 citations

Age-dependent mast-cell-mediated angiogenesis.

1988 • 10 citations