Nuclear–Cytoplasmic Interrelationships

Tissue Differences in the Concentration of Triiodothyronine Nuclear Binding Sites in the Rat: Liver, Kidney, Pituitary, Heart, Brain, Spleen and Testis

1974 • 469 citations

Ribonucleic acid synthesis during the early action of thyroid hormones

1966 • 400 citations

The effect of starvation on the rate of protein synthesis in rat liver and small intestine

1979 • 391 citations

Quantitative Aspects of the Insulin-Receptor Interaction in Liver Plasma Membranes

1974 • 378 citations

Proteins Associated with the Thyroid Hormones

1960 • 358 citations

RNA Processing and the Intervening Sequence Problem

1979 • 353 citations

Regulation of growth hormone messenger RNA by thyroid and glucocorticoid hormones.

1977 • 342 citations

SPECIFIC NUCLEAR TRIIODOTHYRONINE BINDING SITES IN RAT LIVER AND KIDNEY¹

1972 • 336 citations

Post-Transcriptional and Translational Controls of Gene Expression in Eukaryotes

1978 • 271 citations

Thyroid Hormone Action IN VITRO CHARACTERIZATION OF SOLUBILIZED NUCLEAR RECEPTORS FROM RAT LIVER AND CULTURED GH1 CELLS

1974 • 229 citations

Actions of Hormones on Molecular Processes

1965 • 223 citations

Inhibition of the Biological Action of Thyroid Hormones by Actinomycin D and Puromycin

1963 • 220 citations

Triiodothyronine Binding to Isolated Liver Cell Nuclei

1975 • 207 citations

Thyroid Hormone Action at the Cell Level

1979 • 206 citations

Effect of thyroid hormones on the level of the hepatic mRNA for α_2u globulin

1976 • 201 citations

The induction of ovalbumin and conalbumin mRNA by estrogen and progesterone in chick oviduct explant cultures

1978 • 200 citations

Hormone Receptors

1979 • 197 citations

Limited Capacity Binding Sites for l-Triiodothyronine in Rat Liver Nuclei

1973 • 185 citations

Thyroid hormone receptors. Binding characteristics and lack of hormonal dependency for nuclear localization

1975 • 182 citations

Solubilized nuclear "receptors" for thyroid hormones. Physical characteristics and binding properties, evidence for multiple forms.

1976 • 173 citations

Thyroid and glucocorticoid hormones synergistically control growth hormone mRNA in cultured GH1 cells.

1978 • 169 citations

High affinity thyroid hormone binding sites on purified rat liver plasma membranes

1977 • 166 citations

Limited Binding Capacity Sites for l-Triiodothyronine in Rat Liver Nuclei

1974 • 160 citations

Stimulation of hepatic mitochondrial alpha-glycerophosphate dehydrogenase and malic enzyme by L-triiodothyronine. Characteristics of the response with specific nuclear thyroid hormone binding sites fully saturated.

1977 • 151 citations

Thyroid hormone stimulates de novo growth hormone synthesis in cultured GH1 cells: evidence for the accumulation of a rate limiting RNA species in the induction process.

1976 • 148 citations

Ovalbumin Messenger RNA of Chick Oviduct: Partial Characterization, Estrogen Dependence, and Translation In Vitro

1972 • 145 citations

Dose-dependent depletion of nuclear receptors by L-triiodothyronine: evidence for a role in induction of growth hormone synthesis in cultured GH1 cells.

1976 • 139 citations

Proof of the hepatic synthesis of a sex-dependent protein in the rat☆

1966 • 137 citations

Messenger RNA for Hepatic Tryptophan Oxygenase: Its Partial Purification, Its Translation in a Heterologous Cell-free System, and Its Control by Glucocorticoid Hormones

1973 • 137 citations

In Vivo Rate of Translation by Ribosomes of Normal and Regenerating Liver

1974 • 135 citations

Androgenic Control of a Sex-dependent Protein in the Rat

1967 • 124 citations

Modulation of thyroid hormone nuclear receptor levels by 3,5,3'-triiodo-L-thyronine in GH1 cells. Evidence for two functional components of nuclear-bound receptor and relationship to the induction of growth hormone synthesis.

1977 • 124 citations

Relationship of receptor affinity to the modulation of thyroid hormone nuclear receptor levels and growth hormone synthesis by L-triiodothyronine and iodothyronine analogues in cultured GH1 cells.

1979 • 123 citations

Thyroid hormone binding by a component of mitochondrial membrane.

1975 • 122 citations

Cooperation of Mitochondrial and Nuclear Genes Specifying the Mitochondrial Genetic Apparatus in Neurospora crassa

1972 • 122 citations

Mitochondrial Thyroid Hormone Receptor: Localization and Physiological Significance

1978 • 121 citations

Fasting Decreases Triiodothyronine Receptor Capacity

1978 • 120 citations

In vitro binding of L-triiodothyronine to receptors in rat liver nuclei. Kinectics of binding, extraction properties, and lack of requirement for cytosol proteins.

1975 • 115 citations

Mechanism of early effect of hydrocortisone on the transcriptional process: Stimulation of the activities of purified rat liver nucleolar RNA polymerases

1971 • 110 citations

Quantitative Aspects of Iodothyronine Binding by Cytosol Proteins of Rat Liver and Kidney

1974 • 109 citations

Effects of estrogen on gene expression in the chick oviduct. IV. Initiation of RNA synthesis on DNA and chromatin.

1975 • 109 citations

CONTROL OF MITOCHONDRIAL TURNOVER UNDER THE INFLUENCE OF THYROID HORMONE

1971 • 106 citations

Thyroid hormone action: Stimulation of growth hormone and inhibition of prolactin secretion in cultured GH1 cells

1974 • 106 citations

Reduction in Hepatic Triiodothyronine Binding Capacity Induced by Fasting

1977 • 104 citations

The Rapid Turnover of RNA Polymerase of Rat Liver Nucleolus, and of Its Messenger RNA

1972 • 101 citations

Effect of thyroid hormone analogues on the displacement of 125I-L-triiodothyronine from hepatic and heart nuclei in vivo: Possible relationship to hormonal activity

1973 • 100 citations

Reduced nuclear triiodothyronine receptors in starvation-induced hypothyroidism

1977 • 99 citations

How specific are nuclear “receptors” for thyroid hormones?

1975 • 96 citations

Binding of T₃in Rat Liver Nuclei

1974 • 91 citations

Identification of Rat Urinary Proteins by Zone and Immunoelectrophoresis.

1966 • 88 citations

Abnormalities of Triiodothyronine Binding to Lymphocyte and Fibroblast Nuclei from a Patient with Peripheral Tissue Resistance to Thyroid Hormone Action*

1978 • 87 citations

Induction of Mitochondrial RNA Polymerase in Neurospora crassa

1972 • 87 citations

Metabolism of L-Thyroxine (T₄) and L-Triiodothyronine (T₃) by Human Fibroblasts in Tissue Culture: Evidence for Cellular Binding Proteins and Conversion of T₄to T₃

1972 • 85 citations

ANDROGEN-DEPENDENT SYNTHESIS OF α2u GLOBULIN IN THE RAT: ROLE OF THE PITUITARY GLAND

1973 • 85 citations

Nuclear Binding Capacity Appears to Limit the Hepatic Response to L-Triiodothyronine (T₃)

1975 • 84 citations

Estrogen Receptor in Adult Male Rat Liver*

1978 • 84 citations

A short lived polypeptide component of one of two discrete functional pools of hepatic nuclear α-amanitin resistant RNA polymerases

1974 • 79 citations

Effects of estrogen on gene expression in chick oviduct: nuclear receptor levels and initiation of transcription.

1975 • 79 citations

Influence of Heparin on Serum Free Thyroxine¹

1969 • 78 citations

Uptake of L-tri-iodothyronine by isolated rat liver cells. A process partially inhibited by metabolic inhibitors; attempts to distinguish between uptake and binding to intracellular proteins

1979 • 78 citations

Physical Properties of a Dog Liver and Kidney Cytosol Protein That Binds Thyroid Hormone

1974 • 76 citations

A Partial Sequence of Nuclear Events in Regenerating Rat Liver

1972 • 71 citations

The Effect of Triiodothyronine on 2-Deoxy-D-[l-³H]Glucose Uptake in Cultured Chick Embryo Heart Cells*

1977 • 70 citations

Stimulation of nuclear RNA polymerase during the latent period of action of thyroid hormones

1963 • 69 citations

Selective alterations in hepatic enzyme response after reduction of nuclear triiodothyronine receptor sites by partial hepatectomy and starvation

1978 • 66 citations

Thyroid Hormone Receptors from Liver Nuclei: Characteristics of Receptor from Normal, Thyroidectomized, and Triiodothyronine-Treated Rats; Measurement of Occupied and Unoccupied Receptors, and Chromatin Binding of Receptors*

1978 • 65 citations

High affinity thyroxine binding to purified rat liver plasma membranes

1979 • 64 citations

Thyroid Hormone Receptors: Release of Receptor to the Medium Duringin VitroIncubation of Isolated Rat Liver Nuclei

1977 • 64 citations

Estrogen-Induced Changes in Translation, and Specific Messenger RNA Levels during Oviduct Differentiation

1972 • 63 citations

Nuclear Triiodothyronine-Binding Protein: Partial Characterization and Binding to Chromatin

1974 • 63 citations

Cycloleucine Transport in Isolated Rat Thymocytes:In VitroEffects of Triiodothyronine and Thyroxine

1975 • 63 citations

The Effects of Actinomycin D, Puromycin, Cycloheximide and Hydroxyurea on 3′,5,3-Triiodo-L-thyronine Stimulated 2-Deoxy-D-glucose Uptake in Chick Embryo Heart Cellsin Vitro*†

1977 • 61 citations

Specific binding proteins of thyroxine and triiodothyronine in liver soluble proteins

1970 • 60 citations

Comparison of the Response Characteristics of Four Lipogenic Enzymes to 3,5,3′-Triiodothyronine Administration: Evidence for Variable Degrees of Amplification of the Nuclear 3,5,3′-Triiodothyronine Signal*

1980 • 58 citations

Triiodothyronine Receptors During Maturation

1977 • 53 citations

Development-related changes of triiodothyronine binding to brain cytosol receptors

1977 • 52 citations

Messenger RNA content and complexity of euthyroid and hypothyroid rat liver

1979 • 52 citations

Inactive mRNA-protein complexes from mouse sarcoma-180 ascites cells.

1979 • 48 citations

Triiodothyronine-Stimulated Formation of Poly(A)-Containing Nuclear RNA and mRNA in Rat Liver*

1978 • 48 citations

Stimulation of the Uptake of α-Aminoisobutyric Acid in Rat Thymocytes by L-Triiodothyronine: A Comparison with Insulin and Dibutyryl Cyclic AMP

1975 • 48 citations

A cellular thyroxine-binding protein fraction

1958 • 47 citations

Glucagon Influences the Expression of Thyroid Hormone Action: Discrepancy between Nuclear Triiodothyronine Receptor Number and Enzyme Responses*

1979 • 47 citations

GLUCAGON ADMINISTRATION DECREASES HEPATIC NUCLEAR TRIIODOTHYRONINE BINDING CAPACITY

1978 • 47 citations

Sequential Stimulation of Nuclear RNA Polymerase Activities in Livers from Thyroidectomized Rats Treated with Triiodothyronine

1975 • 45 citations

Cycloheximide inhibition of hormonal induction of alpha 2u-globulin mRNA.

1979 • 44 citations

Enzyme synthesis in the regulation of hepatic ‘malic’ enzyme activity

1974 • 44 citations

Triiodothyronine Stimulation of Nuclear Protein Synthesis*

1978 • 44 citations

FACTORS INFLUENCING TRIIODOTHYRONINE BINDING PROPERTIES OF LIVER NUCLEAR RECEPTORS

1976 • 43 citations

Stimulation of amino acid incorporation into protein by isolated mitochondria from rats treated with thyroid hormones

1963 • 43 citations

Levels of rat glucose-6-phosphate dehydrogenase messenger RNA.

1978 • 43 citations

Accelerated synthesis and turnover of nuclear and cytoplasmic RNA during the latent period of action of thyroid hormone

1964 • 43 citations

Triiodothyronine Stimulates Nuclear RNA Synthesis

1977 • 42 citations

Thyroxine binding to soluble proteins in rat liver and its sex dependence

1971 • 41 citations

Tri-iodothyronine-induced increase in rat liver nuclear thyroid-hormone receptors associated with increased mitochondrial α-glycerophosphate dehydrogenase activity

1979 • 40 citations

Thyroid Hormones: Control of Terminal Oxidation

1963 • 39 citations

Nucleolar RNA synthesis in the liver of partially hepatectomized and cortisol-treated rats

1975 • 36 citations

Effect of cycloheximide on the induction of tryptophan oxygenase mRNA by hydrocortisone invivo

1978 • 36 citations

Glucocorticoid induction of alpha2u-globulin protein synthesis and its mRNA in rat hepatocytes in vitro

1978 • 35 citations

The Effect of Thyroid Hormone on in Vitro Rat Liver Mitochondrial RNA Synthesis

1977 • 35 citations

Triiodothyronine binding proteins in rat liver cytosol

1975 • 35 citations

Triiodothyronine Action on RNA Synthesis in Rat‐Liver Mitochondria

1972 • 34 citations

Regulation of activity of chromatin receptors for thyroid hormone: possible involvement of histone-like proteins.

1979 • 33 citations

Nuclear receptors for thyroid hormone

1978 • 31 citations

Increases in the activity of the solubilized rat liver nuclear RNA polymerases following partial hepatectomy

1975 • 31 citations

Ligandin and Z protein in binding of thyroid hormones by the liver

1976 • 31 citations

Mitochondrial Binding Sites for Triiodothyronine

1978 • 31 citations

Immunochemical studies on malate dehydrogenase (decarboxylating) (NADP)

1971 • 29 citations

Hormonal control of transcription in the rat uterus. Stimulation of deoxyribonucleic acid-dependent RNA polymerase III by estradiol.

1977 • 27 citations

Metal ion dependence of the binding of triiodothyronine by cytosol proteins of bullfrog tadpole tissues.

1975 • 27 citations

Triiodothyronine binding to brain cytosol receptors during maturation

1978 • 26 citations

BINDING OF THYROID HORMONES TO A SOLUBLE FRACTION FROM PORCINE ANTERIOR PITUITARY

1973 • 25 citations

Common Clinical Indices of Thyroid Hormone Action: Relationships to Serum Free 3,5,3'-Triiodothyronine Concentration and Estimated Nuclear Occupancy*

1980 • 24 citations

In Vivo Synthesis of Nuclear Protein During Growth of the Liver Induced by Hormones

1966 • 24 citations

Participation of tRNA in regulation of protein biosynthesis at the translational level in eukaryotes

1979 • 23 citations

Attenuation as a general mechanism for the regulation of differential gene transcription in eukaryotes

1979 • 23 citations

Description and Partial Characterization of Thyroid Hormone-Specific and Thyroid Hormone-Dependent Rat Liver Nuclear Proteins*

1980 • 22 citations

Mechanisms of Chromatin Activation and Repression

1977 • 22 citations

Hypothyroidism-Induced Changes in Triiodothyronine Binding to Nuclei and Cytosol-Binding Proteins in Rat Liver*

1978 • 22 citations

Sequential changes in rat liver nuclear tri-iodothyronine receptors and mitochondrial α-glycerophosphate dehydrogenase activity after administeration of tri-iodothyronine

1979 • 21 citations

Electrophoretic characterization of cellular thyroxine-binding proteins: Skeletal muscle and brain of rabbit

1962 • 21 citations

Modification of rat liver RNA polymerase I after in vivo stimulation by hydrocortisone or methylisobutylxanthine

1978 • 20 citations

Stability of Nuclear Triiodothyronine Binding Sites

1977 • 19 citations

T3 receptor occupancy and metabolic responses

1979 • 19 citations

Alpha-Amanitin Administration Results in a Temporary Inhibition of Hepatic Enzyme Induction by Triiodothyronine: Further Evidence Favoring a Long-Lived Mediator of Thyroid Hormone Action

1977 • 18 citations

In vitro triiodothyronine binding to cytoplasmic proteins from human red blood cells

1979 • 17 citations

The early enhancement of rat liver deoxyribonucleic acid-dependent ribonucleic acid polymerase II activity by tri-iodothyronine

1975 • 17 citations

Stimulation of mitochondrial RNA synthesis by thyroid hormone

1970 • 16 citations

Demonstration and Some Properties of Cytosol-Binding Proteins for Thyroxine and Triiodothyronine in Human Liver

1976 • 15 citations

Early Effects of Thyrotropin on Ribonucleic Acid Transcription in the Thyroid*

1979 • 14 citations

Increased RNA Polymerase Activity in Isolated Liver Nucleoli from Thyroidectomized Rats Treated with Triiodothyronine

1977 • 13 citations

Pure estrogen receptor complexes stimulate RNA transcription invitro

1979 • 12 citations

Glucocorticoid and thyroid hormone‐binding to nuclear ribonucleoprotein particles

1977 • 11 citations

EARLY IN VITRO INDUCTION OF RAT PITUITARY GH mRNA BY T₃1

1978 • 11 citations

Intracellular thyroxine-binding proteins in rabbit muscle and liver

1974 • 7 citations

Growth hormone and drug metabolism. Acute effects on nuclear ribonucleic acid polymerase activity and chromatin

1976 • 7 citations

Binding of¹³¹I-Labeled Thyroxine and Triiodothyronine by Aqueous Dispersions of Thyrotropic and Mammotropic Tumors

1964 • 6 citations

ULTRACENTRIFUGAL CHARACTERIZATION OF CYTOSOL-BINDING PROTEINS FOR THYROXINE AND TRIIODOTHYRONINE IN HUMAN LIVER

1977 • 5 citations

Uptake of T3 receptor complex by liver cell nuclei in vitro

1980 • 4 citations

Effect of triiodothyronine and of cytosol on the hormone binding to rat liver nuclear non histone proteins

1976 • 4 citations

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