Laboratory Diagnosis of Lyme Disease

The Spirochetal Etiology of Lyme Disease

1983 • 1,590 citations

Spirochetes Isolated from the Blood of Two Patients with Lyme Disease

1983 • 810 citations

Biology of Borrelia species

1986 • 577 citations

Antibody Response in Lyme Disease: Evaluation of Diagnostic Tests

1984 • 404 citations

Seronegative Lyme Disease

1988 • 379 citations

Antigens of Borrelia burgdorferi recognized during Lyme disease. Appearance of a new immunoglobulin M response and expansion of the immunoglobulin G response late in the illness.

1986 • 374 citations

A Borrelia-specific monoclonal antibody binds to a flagellar epitope

1986 • 369 citations

Heterogeneity of Major Proteins in Lyme Disease Borreliae: A Molecular Analysis of North American and European Isolates

1985 • 365 citations

Bacteriology of experimental gingivitis in young adult humans

1982 • 335 citations

Cross-Reactivity in Serological Tests for Lyme Disease and Other Spirochetal Infections

1987 • 317 citations

Antigenic Variability of Borrelia burgdorferi

1988 • 298 citations

Comparison of Immunoblotting and Indirect Enzyme-Linked Immunosorbent Assay Using Different Antigen Preparations for Diagnosing Early Lyme Disease

1988 • 294 citations

Enzyme-Linked Immunosorbent Assay and Indirect Immunofluorescence Assay for Lyme Disease

1984 • 291 citations

Variation in a major surface protein of Lyme disease spirochetes

1984 • 280 citations

LASERS IN THE LABORATORY

1964 • 269 citations

Measurement of antibodies to the Borrelia burgdorferi flagellum improves serodiagnosis in Lyme disease

1988 • 264 citations

Longitudinal Assessment of the Clinical and Epidemiological Features of Lyme Disease in a Defined Population

1986 • 227 citations

The spirochetal etiology of acrodermatitis chronica atrophicans Herxheimer

1984 • 222 citations

Quantitative relationship of Treponema denticola to severity of periodontal disease

1988 • 220 citations

Intrathecal Production of Specific Antibodies against Borrelia burgdorferi in Patients with Lymphocytic Meningoradiculitis (Bannwarth's Syndrome)

1986 • 215 citations

Isolation of Antigenic Components from the Lyme Disease Spirochete: Their Role in Early Diagnosis

1987 • 203 citations

Diagnosis of spirochetal meningitis by enzyme-linked immunosorbent assay and indirect immunofluorescence assay in serum and cerebrospinal fluid

1985 • 194 citations

Antibodies of patients with Lyme disease to components of the Ixodes dammini spirochete.

1983 • 191 citations

Comparison of an indirect fluorescent-antibody test with an enzyme-linked immunosorbent assay for serological studies of Lyme disease

1984 • 191 citations

Diagnosing early lyme disease

1985 • 185 citations

Successful Cultivation of Spirochetes from Skin Lesions of Patients With Erythema Chronicum Migrans Afzelius and Acrodermatitis Chronica Atrophicans

1985 • 184 citations

Immunochemical characterization of and isolation of the gene for a Borrelia burgdorferi immunodominant 60-kilodalton antigen common to a wide range of bacteria

1988 • 178 citations

Borrelia burgdorferi in Joint Fluid in Chronic Lyme Arthritis

1986 • 170 citations

Serological diagnosis of erythema migrans disease and related disorders

1984 • 156 citations

Bacteriology of experimental gingivitis in children

1984 • 154 citations

Antigenically variable Borrelia burgdorferi isolated from cottontail rabbits and Ixodes dentatus in rural and urban areas

1989 • 150 citations

Genetic relationship of lyme disease spirochetes to Borrelia, Treponema, and Leptospira spp

1984 • 144 citations

Characterization of Borrelia burgdorferi strains isolated from Ixodes pacificus ticks in California

1987 • 140 citations

Correlation of Serum and Cryoglobulin IgM with Activity, and Serum IgG with Remission

1979 • 137 citations

A Prospective Study of Tick Bites in an Endemic Area for Lyme Disease

1989 • 136 citations

Identification of endemic foci of Lyme disease: isolation of Borrelia burgdorferi from feral rodents and ticks (Dermacentor variabilis)

1985 • 133 citations

Serodiagnosis of Early Lyme Disease: Analysis of IgM and IgG Antibody Responses by Using an Antibody-Capture Enzyme Immunoassay

1988 • 130 citations

Serodiagnosis of erythema migrans and acrodermatitis chronica atrophicans by the Borrelia burgdorferi flagellum enzyme-linked immunosorbent assay

1989 • 121 citations

An Interlaboratory Study of Antibody to Borrelia burgdorferi

1987 • 115 citations

Enzyme-Linked Immunosorbent Assays for Lyme Disease: Reactivity of Subunits of Borrelia burgdorferi

1989 • 111 citations

Lyme disease patients' serum contains IgM antibodies to Borrelia burgdorferi that cross‐react with neuronal antigens

1988 • 104 citations

Detection of antigens in urine of mice and humans infected with Borrelia burgdorferi, etiologic agent of Lyme disease

1989 • 102 citations

Serological Evidence for Simultaneous Occurrences of Lyme Disease and Babesiosis

1985 • 100 citations

TICKS PARASITIZING HUMANS IN A LYME DISEASE ENDEMIC AREA OF SOUTHERN NEW YORK STATE

1988 • 98 citations

Mechanisms of Cell Killing/Cytopathic Effects by Nonhuman Retroviruses

1988 • 97 citations

Borrelia burgdorferi—specific and autoreactive T‐cell lines from cerebrospinal fluid in lyme radiculomyelitis

1988 • 97 citations

Polymorphisms of major surface proteins of Borrelia burgdorferi

1986 • 95 citations

Evaluation of Sera from Patients with Lyme Disease in the Fluorescent Treponemal Antibody-absorption Test for Syphilis

1986 • 75 citations

Serodiagnosis of Syphilis by an Enzyme‐Linked Immunosorbent Assay for IgG Antibodies Against the Reiter Treponeme Flagellum

1982 • 74 citations

ENZYME-LINKED IMMUNOSORBENT ASSAYS FOR THE DETECTION OF CLASS-SPECIFIC IMMUNOGLOBULINS TO BORRELIA BURGDORFERI1

1988 • 65 citations

Serologic Diagnosis of Lyme Disease

1988 • 64 citations

Antigenic cross-reactivity between Treponema pallidum and other pathogenic members of the family Spirochaetaceae

1984 • 64 citations

A murine IgM monoclonal antibody binds an antigenic determinant in outer surface protein A, an immunodominant basic protein of the Lyme disease spirochete.

1988 • 60 citations

Lyme Borreliosis in the Soviet Union: A Cooperative US-USSR Report

1988 • 53 citations

Immunodiagnostic tests for Lyme disease.

1984 • 49 citations

Immunochemische analyse der immunantwort bei spätmanifestationen der Lyme Borreliose

1988 • 49 citations

Cellular immune findings in Lyme disease Correlation with serum IgM and disease activity

1984 • 48 citations

In vivo and in vitro evidence of B cell hyperactivity during Lyme disease.

1988 • 40 citations

Ticks, Spirochetes, and New Diagnostic Tests for Lyme Disease

1985 • 37 citations

Enzyme-linked immunosorbent assay for detection of antibodies to the venereal disease research laboratory (VDRL) antigen in syphilis

1987 • 36 citations

Demonstration of the Lyme Disease Spirochete by a Modified Dieterle Stain Method

1985 • 35 citations

Lyme disease and related disorders.

1985 • 33 citations

Lymphocytic meningoradiculitis and encephalomyelitis due to Borrelia burgdorferi: a clinical and serological study of 18 cases.

1987 • 29 citations

Characterization of antibody response in patients with Borrelia meningitis

1988 • 28 citations

Antigenic Variation of Surface Proteins of Borrelia Species

1988 • 28 citations

Detection of Borrelia in acridine orange-stained blood smears by fluorescence microscopy.

1983 • 28 citations

Use of an autologous antigen in the serologic testing of patients with erythema migrans of Lyme disease

1988 • 25 citations

Early detection and persistence of antibodies to Borrelia burgdorferi in persons with Lyme disease

1987 • 23 citations

Lyme Disease—Connecticut

1988 • 22 citations

In vivo and in vitro evidence of B cell hyperactivity during Lyme disease.

1988 • 14 citations

Use of avidin-biotinylated horseradish peroxidase complex for visualization of spirochetes

1983 • 6 citations