Alpha-subunits of Gs and Gi in adipocyte plasma membranes of genetically diabetic (db/db) mice

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice

1978 • 1,274 citations

Hypothalamic and genetic obesity in experimental animals: an autonomic and endocrine hypothesis.

1979 • 1,145 citations

G Proteins: A Family of Signal Transducers

1986 • 975 citations

Gi2 mediates alpha 2-adrenergic inhibition of adenylyl cyclase in platelet membranes: in situ identification with G alpha C-terminal antibodies.

1989 • 374 citations

Abolition of the expression of inhibitory guanine nucleotide regulatory protein Gi activity in diabetes

1987 • 232 citations

Chronic ethanol causes heterologous desensitization of receptors by reducing αsmessenger RNA

1988 • 220 citations

Mutations of Gs α Designed to Alter the Reactivity of the Protein with Bacterial Toxins

1989 • 177 citations

Stoichiometry of receptor‐G _s ‐adenylate cyclase interactions

1991 • 139 citations

Cholera Toxin Induces cAMP-independent Degradation of Gs

1989 • 104 citations

Dexamethasone Increases Adenylyl Cyclase Activity and Expression of the α-Subunit of G_sin GH₃Cells*

1987 • 83 citations

Steady-state levels of G-proteins and beta-adrenergic receptors in rat fat cells. Permissive effects of thyroid hormones.

1988 • 83 citations

Reduced expression of multiple forms of the alpha subunit of the stimulatory GTP-binding protein in pseudohypoparathyroidism type Ia.

1987 • 77 citations

Thyroid Hormones Regulate G-protein β-Subunit mRNA Expression in Vivo

1989 • 72 citations

Increase in Gs and cyclic AMP generation in HIT cells

1989 • 72 citations

Pertussis toxin induces structural changes in G alpha proteins independently of ADP-ribosylation.

1989 • 54 citations

Absence of the inhibitory effect of guanine nucleotides on adenylate cyclase activity in white adipocyte membranes of the ob/ob mouse. Effect of the ob gene.

1985 • 49 citations

Multiple defects occur in the guanine nucleotide regulatory protein system in liver plasma membranes of obese (fa/fa) but not lean (Fa/Fa) zucker rats: Loss of functional G1 and abnormal Gs function

1989 • 41 citations

Concurrent up-regulation of guanine-nucleotide-binding proteins Gi1α, Gi2α and Gi3α in adipocytes of hypothyroid rats

1990 • 34 citations

Quantification of the α and β subunits of the transducing elements (Gs and Gi) of adenylate cyclase in adipocyte membranes from lean and obese (ob/ob) mice

1990 • 33 citations

Adipocyte G-proteins and adenylate cyclase. Effects of adrenalectomy

1989 • 33 citations

Guanine-nucleotide-binding proteins Gi and Gs in fat-cells from normal, hypothyroid and obese human subjects

1989 • 27 citations

Genetically acquired diabetes: adipocyte guanine nucleotide regulatory protein expression and adenylate cyclase regulation

1991 • 21 citations

Evidence for altered expression of the GTP-dependent regulatory proteins, Gs and Gi, in adipocytes from aged rats

1989 • 17 citations

Winner of the 1988 NAASO Young Investigator Award. Regulation of fat cell adenylate cyclase in young Zucker (fa/fa) rats: alterations in GTP sensitivity of adenosine A1 mediated inhibition.

1990 • 11 citations

The Function but Not the Expression of Rat Liver Inhibitory Guanine Nucleotide Binding Protein Is Altered in Streptozotocin-Induced Diabetes

1991 • 11 citations