Abnormalities of cholesterol turnover in hypercholesterolemic (type II) patients.

Statistical methods

1967 • 19,533 citations

A SIMPLIFIED METHOD FOR THE ESTIMATION OF TOTAL CHOLESTEROL IN SERUM AND DEMONSTRATION OF ITS SPECIFICITY

1952 • 3,146 citations

Binding and Degradation of Low Density Lipoproteins by Cultured Human Fibroblasts

1974 • 1,481 citations

Classification of Hyperlipidaemias and Hyperlipoproteinaemias ,

1972 • 843 citations

The metabolism of low density lipoprotein in familial type II hyperlipoproteinemia

1972 • 629 citations

Familial hypercholesterolemia: Defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme a reductase activity

1974 • 589 citations

Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Activity in Cultured Human Fibroblasts

1974 • 545 citations

The Familial Hyperlipoproteinemias

1975 • 538 citations

Anatomy of body water and electrolytes

1959 • 460 citations

Familial Hypercholesterolemia: Identification of a Defect in the Regulation of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Activity Associated with Overproduction of Cholesterol

1973 • 442 citations

Measurements of cholesterol turnover, synthesis, and absorption in man, carried out by isotope kinetic and sterol balance methods

1969 • 323 citations

Effects of dietary cholesterol on the regulation of total body cholesterol in man

1971 • 321 citations

Turnover of plasma cholesterol in man

1968 • 295 citations

The interaction of cholesterol absorption and cholesterol synthesis in man

1969 • 290 citations

Esterification of Low Density Lipoprotein Cholesterol in Human Fibroblasts and Its Absence in Homozygous Familial Hypercholesterolemia

1974 • 287 citations

Classification of Hyperlipidemias and Hyperlipoproteinemias

1972 • 255 citations

Expression of the Familial Hypercholesterolemia Gene in Heterozygotes: Mechanism for a Dominant Disorder in Man

1974 • 253 citations

Distribution and turnover of cholesterol in humans

1969 • 214 citations

BODY CHOLESTEROL METABOLISM IN MAN. I. THE EQUILIBRATION OF SERUM AND TISSUE CHOLESTEROL*†

1962 • 200 citations

Cholesterol Metabolism in Human Obesity

1973 • 152 citations

Three-pool model of the long-term turnover of plasma cholesterol in man

1973 • 142 citations

Determination of Kinetic Parameters in a Two-Pool System by Administration of One or More Tracers^*

1964 • 115 citations

FEEDBACK CONTROL OF CHOLESTEROL SYNTHESIS IN MAN*

1963 • 107 citations

The Intestinal Absorption of Dietary Cholesterol by Hypercholesterolemic (Type II) and Normocholesterolemic Humans

1974 • 104 citations

Differences in Bile Acid Excretion

1969 • 73 citations

BODY CHOLESTEROL METABOLISM IN MAN. II. MEASUREMENT OF THE BODY CHOLESTEROL MISCIBLE POOL AND TURNOVER RATE*†

1962 • 70 citations

Studies in the metabolism of cholesterol in subjects with normal plasma cholesterol levels and in patients with essential hypercholesterolaemia.

1967 • 64 citations

The Formation of Bile Acids in Patients with Three Types of Hyperlipoproteinemia

1972 • 64 citations

Improved estimation of body masses and turnover of cholesterol by computerized input–output analysis

1973 • 63 citations

Low Excretion of Fecal Bile Acids in a Family with Hypercholesterolemia

1967 • 60 citations

Long-term decay of serum cholesterol radioactivity: body cholesterol metabolism in normals and in patients with hyperlipoproteinemia and atherosclerosis

1970 • 59 citations

The Effects of Colestipol Resin and of Colestipol Plus Clofibrate on the Turnover of Plasma Cholesterol in Man

1973 • 54 citations

Dietary Sterols: Their Relationship to Atherosclerosis

1968 • 53 citations

Cholesterol synthesis by cultured fibroblasts: decreased feedback inhibition in familial hypercholesterolemia.

1974 • 48 citations

Long-Term Kinetics of Serum and Xanthoma Cholesterol Radioactivity in Patients with Hypercholesterolemia

1972 • 43 citations

Idiopathic Hypercholesterolemia: Demonstration of an Impaired Feedback Control of Cholesterol Synthesis <i>in vivo</i>

1965 • 36 citations

LACK OF INHIBITION OF HEPATIC CHOLESTEROL SYNTHESIS BY DIETARY CHOLESTEROL IN CASES OF FAMILIAL HYPERCHOLESTEROLÆMIA

1969 • 20 citations

Increased Cholesterol-biosynthesis in Familial Hypercholesterolemia

1971 • 6 citations

Studies on Cholesterol Turnover in Hypercholesterolemic Subjects

1973 • 5 citations

Cholesterol metabolism in a patient with familial Hyper-betalipoproteinaemia during periods of high and low cholesterol intake

1973 • 4 citations