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Mutant p53 is not fully dominant over endogenous wild type p53 in a colorectal adenoma cell line as demonstrated by induction of MDM2 protein and retention of a p53 dependent G1 arrest after gamma irradiation.

Ann C. Williams, Miller Jc, Collard Tj, Bracey Ts, Sabina Cosulich
PubMed

Data up to Jan 2025

Published1995
Citations22
References0
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BiologySociologyCancer researchCell biologyMolecular biology

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Mutant p53 is not fully dominant over endogenous wild type p53 in a colorectal adenoma… (1995) – PubMed | Metascience Observatory Explorer