Anticoagulant effects of retinoic acids on leukemia cells

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

1992 • 1,790 citations

NB4, a maturation inducible cell line with t(15;17) marker isolated from a human acute promyelocytic leukemia (M3)

1991 • 884 citations

Determination of plasma tissue factor antigen and its clinical significance

1994 • 154 citations

The bleeding disorder in acute promyelocytic leukaemia: fibrinolysis due to u‐PA rather than defibrination

1989 • 114 citations

Occurrence of resistance to retinoic acid in the acute promyelocytic leukemia cell line NB4 is associated with altered expression of the pml/RAR alpha protein

1993 • 111 citations

All-trans retinoic acid upregulates thrombomodulin and downregulates tissue-factor expression in acute promyelocytic leukemia cells: distinct expression of thrombomodulin and tissue factor in human leukemic cells

1994 • 101 citations

9-cis retinoic acid induces complete remission but does not reverse clinically acquired retinoid resistance in acute promyelocytic leukemia

1995 • 92 citations

Effects of novel retinoic acid compound, 9-cis-retinoic acid, on proliferation, differentiation, and expression of retinoic acid receptor-alpha and retinoid X receptor-alpha RNA by HL-60 cells

1993 • 92 citations

NB4, a maturation inducible cell line with t(15;17) marker isolated from a human acute promyelocytic leukemia (M3)

1991 • 84 citations

In vivo thrombin and plasmin activities in patients with acute promyelocytic leukemia (APL): effect of all-trans retinoic acid (ATRA) therapy.

1995 • 59 citations

Induction of differentiation of promyelocytic NB4 cells by retinoic acid is associated with rapid increase in urokinase activity subsequently downregulated by production of inhibitors

1994 • 57 citations

Acceleration of the thrombin inactivation of single chain urokinase-type plasminogen activator (pro-urokinase) by thrombomodulin.

1991 • 52 citations

Cancer procoagulant in the human promyelocytic cell line NB4 and its modulation by all-trans-retinoic acid.

1994 • 51 citations

Induction of differentiation of promyelocytic NB4 cells by retinoic acid is associated with rapid increase in urokinase activity subsequently downregulated by production of inhibitors

1994 • 42 citations

Rapid improvement of coagulopathy by all‐trans retinoic acid in acute promyelocytic leukemia

1994 • 41 citations

Thrombomodulin Is a Cofactor for Thrombin Degradation of Recombinant Single-Chain Urokinase Plasminogen Activator "In Vitro" and in a Perfused Rabbit Heart Model

1992 • 33 citations

Relationship between post-translational glycosylation and anticoagulant function of secretable recombinant mutants of human thrombomodulin

1991 • 27 citations

Monoclonal Antibodies to Human Thrombomodulin Whose Binding Is Calcium Dependent

1989 • 26 citations

Thrombomodulin Induction by All-trans Retinoic Acid Is Independent of HL-60 Cells Differentiation to Neutrophilic Cells

1994 • 10 citations

Frequent rearrangements of retinoic acid receptor alpha gene and myl gene, and rare mutations of RAS and FMS genes in acute promyelocytic leukemia

1992 • 9 citations

UP-regulation of tissue factor mRNA in human umbilical vein endothelial cells by calmodulin inhibitor W7

1994 • 4 citations

The biosynthesis of thrombomodulin and its enhancement by dibutyryl cAMP in a human megakaryoblastic cell line, UT-7.

1991 • 3 citations