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Current status of estrogen therapy for the menopause

Data up to Jan 2025

Published1982
Citations101
References182

Total Citations Per Year

Abstract

References (182)

Menopause and Risk of Cardiovascular Disease

1976 • 1,324 citations

Increased Risk of Endometrial Carcinoma among Users of Conjugated Estrogens

1975 • 996 citations

Source of Estrogen Production in Postmenopausal Women1

1973 • 961 citations

Association of Exogenous Estrogen and Endometrial Carcinoma

1975 • 950 citations

LONG-TERM PREVENTION OF POSTMENOPAUSAL OSTEOPOROSIS BY ŒSTROGEN

1976 • 946 citations

Menopause and Coronary Heart Disease

1978 • 890 citations

OUTCOME FOR INFANTS OF VERY LOW BIRTHWEIGHT: SURVEY OF WORLD LITERATURE

1981 • 829 citations

POSTMENOPAUSAL OSTEOPOROSIS

1941 • 822 citations

Decreased Risk of Fractures of the Hip and Lower Forearm with Postmenopausal Use of Estrogen

1980 • 789 citations

ISCHÆMIC HEART-DISEASE IN RELATION TO FASTING VALUES OF PLASMA TRIGLYCERIDES AND CHOLESTEROL

1972 • 770 citations

共やくエクイン・エストロゲン(Premarin)服用閉経婦人の血清エクイリン,エストロン,エストラジオール値

1980 • 725 citations

Hyperlipidemia in Coronary Heart Disease I. LIPID LEVELS IN 500 SURVIVORS OF MYOCARDIAL INFARCTION

1973 • 630 citations

Harrison's Principles of Internal Medicine.

1980 • 600 citations

Estrogens and Endometrial Cancer in a Retirement Community

1976 • 565 citations

Hormonal characteristics of the human menstrual cycle throughout reproductive life.

1975 • 563 citations

The Biology of Senescence

1978 • 539 citations

AN OVARIAN HORMONE

1923 • 465 citations

Estrogen Replacement Therapy II: A Prospective Study in the Relationship to Carcinoma and Cardiovascular and Metabolic Problems

1979 • 451 citations

Effect of Estrogen on Calcium Absorption and Serum Vitamin D Metabolites in Postmenopausal Osteoporosis*

1980 • 433 citations

Control of the Rhesus Monkey Menstrual Cycle: Permissive Role of Hypothalamic Gonadotropin-Releasing Hormone

1980 • 384 citations

Effects of long-term estrogen replacement therapy

1979 • 377 citations

Myocardial infarction in young women with special reference to oral contraceptive practice.

1975 • 373 citations

Estrogen replacement therapy I: a 10-year prospective study in the relationship to osteoporosis.

1979 • 369 citations

MENOPAUSAL OESTROGEN THERAPY AND PROTECTION FROM DEATH FROM ISCHAEMIC HEART DISEASE

1981 • 362 citations

Effects of Different Progestogens on Lipoproteins during Postmenopausal Replacement Therapy

1981 • 353 citations

Menopausal Estrogens and Breast Cancer

1976 • 342 citations

Surgically Confirmed Gallbladder Disease, Venous Thromboembolism, and Breast Tumors in Relation to Postmenopausal Estrogen Therapy

1974 • 333 citations

BONE RESPONSE TO TERMINATION OF ŒSTROGEN TREATMENT

1978 • 329 citations

An Epidemiologic Study of Cervical and Trochanteric Fractures of the Femur in an Urban Population Analysis of 1,664 Cases with Special Reference to Etiologic Factors

1964 • 323 citations

Estrogen-Induced Uterine Responses and Growth: Relationship to Receptor Estrogen Binding by Uterine Nuclei11

1975 • 321 citations

Control of Uterine Estrogen Receptor Levels by Progesterone

1976 • 313 citations

Association of Waking Episodes With Menopausal Hot Flushes

1981 • 300 citations

The Coronary Drug Project

1973 • 298 citations

The Coronary Drug Project

1970 • 285 citations

Estrogen Replacement Therapy

1983 • 271 citations

Alternative Analytic Methods for Case-Control Studies of Estrogens and Endometrial Cancer

1978 • 260 citations

A Case-Control Study of Menopausal Estrogen Therapy and Breast Cancer

1980 • 254 citations

Risk of vascular disease in women. Smoking, oral contraceptives, noncontraceptive estrogens, and other factors

1979 • 253 citations

Effects of long-term estrogen replacement therapy

1979 • 251 citations

Exogenous estrogen and endometrial carcinoma: Case-control and incidence study

1977 • 247 citations

Effects of "natural oestrogen" replacement therapy on menopausal symptoms and blood clotting.

1975 • 245 citations

Semi-security and psychiatric hospitals.

1974 • 240 citations

An Ovarian Hormone

1983 • 240 citations

Incidence of Fractures in Persons over 35 Years of Age: A Report to the M.R.C. Working Party on Fractures in the Elderly

1964 • 231 citations

Menopausal Flushing: Double-blind Trial of a Non-hormonal Medication

1974 • 222 citations

Increasing Incidence of Endometrial Cancer in the United States

1976 • 210 citations

IS INADEQUATE BREAST-FEEDING AN IMPORTANT CAUSE OF FAILURE TO THRIVE?

1979 • 195 citations

Biological Effects of Various Doses of Conjugated Equine Estrogens in Postmenopausal Women*

1980 • 194 citations

Hypertension, Oral Contraceptive Agents, and Conjugated Estrogens

1971 • 187 citations

MORTALITY AMONG WOMEN PARTICIPATING IN THE OXFORD/FAMILY PLANNING ASSOCIATION CONTRACEPTIVE STUDY

1977 • 178 citations

Association of a History of Gallbladder Disease with a Reduced Concentration of High-Density-Lipoprotein Cholesterol

1981 • 176 citations

Myocardial Infarction and Estrogen Therapy in Post-Menopausal Women

1976 • 171 citations

Relations between bleeding pattern, endometrial histology, and oestrogen treatment in menopausal women

1978 • 170 citations

Use of the progestogen challenge test to reduce the risk of endometrial cancer.

1980 • 164 citations

THE INTERCONVERSION OF ESTRONE AND ESTRADIOL BY HUMAN TISSUE SLICES1,2,3

1953 • 163 citations

HORMONAL DYNAMICS ASSOCIATED WITH THE MENOPAUSE

1976 • 159 citations

Absorption of Estrogens from Vaginal Creams

1978 • 158 citations

Consensus on Menopause Research

1976 • 157 citations

Incidence of Endometrial Cancer in Relation to the use of Oral Contraceptives

1980 • 154 citations

Risk of Vascular Disease in Women

1979 • 150 citations

Time interval from castration in premenopausal women to development of excessive coronary atherosclerosis

1967 • 149 citations

Histological effects of progestins on hyperplasia and carcinoma in situ of the endometrium

1959 • 149 citations

NATURAL ŒSTROGEN AS AN EFFECTIVE TREATMENT FOR TYPE-II HYPERLIPOPROTEINÆMIA IN POSTMENOPAUSAL WOMEN

1978 • 148 citations

THE DEPRESSION OF ESTRONE-INDUCED UTERINE GROWTH BY PHENOLIC ESTROGENS WITH OXYGENATED FUNCTIONS AT POSITIONS 6 OR 16: THE IMPEDED ESTROGENS

1955 • 144 citations

�ber ?Progynon? ein krystallisiertes weibliches Sexualhormon

1929 • 142 citations

The effect of estrogens on carbohydrate metabolism: Glucose, insulin, and growth hormone studies on one hundred and seventy-one women ingesting Premarin, mestranol, and ethinyl estradiol for six months

1972 • 127 citations

Decreased Risk of Endometrial Cancer among Oral-Contraceptive Users

1980 • 126 citations

Endometrial carcinoma in young women taking oral contraceptive agents.

1975 • 126 citations

METABOLIC AND HORMONAL EFFECTS OF POST-MENOPAUSAL OESTROGEN REPLACEMENT TREATMENT

1977 • 122 citations

A Review of the Prolonged Use of Estrogens and Androgens in Postmenopausal and Senile Osteoporosis

1957 • 120 citations

CORONARY RISK AND ESTROGEN USE IN POSTMENOPAUSAL WOMEN1

1978 • 117 citations

Gonadotropins, Estrogens, and Adrenal Steroids during the Menopausal Hot Flash*

1980 • 112 citations

Exogenous Hormones, Reproductive History, and Breast Cancer 2

1977 • 108 citations

LOSS OF COMPACT BONE DUE TO MENOPAUSE

1966 • 107 citations

Endocrine factors in endometrial carcinoma

1967 • 106 citations

Oral Contraceptives and Blood Pressure

1977 • 103 citations

Depression in the Menopause

1973 • 102 citations

Coronary heart disease in relation to age, sex, and the menopause.

1978 • 100 citations

The effect of intrauterine devices, oral contraceptives, estrogens, and progestogens on blood pressure

1972 • 99 citations

Metabolic Bone Diseases

2019 • 97 citations

The effects of oestrogens and progestogens on the postmenopausal endometrium

1978 • 94 citations

PERITONEAL DIALYSIS IN MALARIA

1967 • 94 citations

Noncontraceptive estrogens and myocardial infarction in young women.

1980 • 93 citations

Heart Disease Risk Factors and Hormone Use in Postmenopausal Women

1979 • 93 citations

The use of medroxyprogesterone acetate for relief of climacteric symtoms

1980 • 91 citations

Objectively Recorded Hot Flushes in Patients with Pituitary Insufficiency*

1981 • 91 citations

MORTALITY AMONG ORAL-CONTRACEPTIVE USERS

1977 • 90 citations

Effect of exogenous estrogen on serum pregnenolone, cortisol, and androgens in postmenopausal women.

1975 • 86 citations

Three-Year Changes in Bone Mineral Mass of Postmenopausal Osteoporotic Patients Based on Neutron Activation Analysis of the Central Third of the Skeleton*

1981 • 86 citations

Elevations in skin temperature of the finger as an objective index of postmenopausal hot flashes: Standardization of the technique

1979 • 84 citations

Die Ovarientransplantation

1900 • 81 citations

Hot flushes after hypophysectomy.

1977 • 81 citations

Estrogen use, hypertension and stroke in postmenopausal women

1978 • 76 citations

Objective techniques for the assessment of postmenopausal hot flashes.

1981 • 75 citations

The "Sodium Retaining Effect" of the Sex Hormones

1937 • 71 citations

Objective evidence that placebo and oral medroxyprogesterone acetate therapy diminish menopausal vasomotor flushes

1981 • 71 citations

Plasma estrone sulfate levels in postmenopausal women

1980 • 69 citations

THE INCIDENCE OF OSTEOPOROSIS IN PATIENTS WITH FEMORAL NECK FRACTURE

1962 • 68 citations

Metabolic, Hormonal, and Vascular Changes after Synthetic Oestrogen Therapy in Oophorectomized Women

1971 • 67 citations

Effect of postmenopausal estrogen therapy on diastolic blood pressure and bodyweight

1978 • 67 citations

Changing trends and prognostic features in endometrial cancer associated with exogenous estrogen therapy.

1979 • 67 citations

Œstrogenic Activity of Alkylated Stilœstrols

1938 • 67 citations

Effects of Contraceptive Steroids on Carbohydrate Metabolism

1968 • 66 citations

Non-linear bone loss in oophorectomized women

1977 • 65 citations

Conjugated equine oestrogens and blood clotting: a follow-up report.

1977 • 60 citations

Systemic Absorption and Sustained Effects of Vaginal Estrogen Creams

1979 • 60 citations

The etiology of fractured hips in females.

1968 • 59 citations

Oral contraception and thrombo-embolic disease.

1967 • 56 citations

Noncontraceptive Estrogens and Myocardial Infarction in Young Women

1980 • 54 citations

Subdermal estradiol pellets following hysterectomy and oophorectomy. Effect upon serum estrone, estradiol, luteinizing hormone, follicle-stimulating hormone, corticosteroid binding globulin-binding capacity, testosterone-estradiol binding globulin-binding capacity, lipids, and hot flushes.

1980 • 53 citations

ANTITHROMBIN III AND THE ŒSTROGEN CONTENT OF COMBINED ŒSTRO-PROGESTAGEN CONTRACEPTIVES

1972 • 51 citations

Menopausal bone loss and estrogen replacement.

1976 • 49 citations

The mental tonic effect of oestrogens administered to oöphorectomized females.

1972 • 48 citations

The Effects of Long-Term Estrogen Administration to Women following Hysterectomy

2015 • 48 citations

Subdermal estradiol pellets following hysterectomy and oophorectomy

1980 • 48 citations

A STUDY OF THE EFFECTIVENESS OF PROPRANOLOL IN MENOPAUSAL HOT FLUSHES

1978 • 48 citations

Plasma hormone profiles after the menopause and bilateral oöphorectomy.

1978 • 45 citations

Comparison of serum oestrogen concentrations in post-menopausal women taking oestrone sulphate and oestradiol.

1978 • 43 citations

Mortality among oral-contraceptive users. Royal College of General Practitioners' Oral Contraception Study.

1977 • 43 citations

Failure of response of menopausal vasomotor symptoms to clonidine

1978 • 42 citations

Twin Pregnancy: The Role of Active Management During Pregnancy and Delivery

1975 • 42 citations

SERUM EQUILIN, ŒSTRONE, AND ŒSTRADIOL LEVELS IN POSTMENOPAUSAL WOMEN RECEIVING CONJUGATED EQUINE ŒSTROGENS ('PREMARIN')

1980 • 40 citations

V. Contributions to the physiology of mammalian reproduction. Part I.—The œstrous cycle in the dog. Part II.—The ovary as an organ of internal secretion

1906 • 38 citations

COMPARISON OF THE ANTI-FERTILITY AND SEX HORMONAL ACTIVITIES OF SEX HORMONES AND THEIR DERIVATIVES

1964 • 38 citations

Radioimmunoassay of Plasma Equilin and Estrone in Postmenopausal Women after the Administration of Premarin*

1981 • 37 citations

Comparison between degree of systemic absorption of vaginally and orally administered estrogens at different dose levels in postmenopausal women

1981 • 37 citations

THE RELATION BETWEEN PLASMA AND ROSTENEDIONE AND OESTRONE LEVELS IN UNTREATED AND CORTICOSTEROID‐TREATED POST‐MENOPAUSAL WOMEN

1978 • 37 citations

The Crystalline Ovarian Follicular Hormone

1935 • 36 citations

The Effect of Conjugated Estrogens on the Renin-Angiotensin System

1977 • 36 citations

A NEW AND SENSITIVE METHOD FOR QUANTIFYING AND COMPARING THE BIOLOGICAL POTENCY OF VARIOUS ESTROGENS IN MAN

1979 • 35 citations

Oestrogens and Calcium Metabolism

2015 • 35 citations

EFFECT OF HORMONE REPLACEMENT THERAPY ON GLUCOSE TOLERANCE IN POSTMENOPAUSAL WOMEN

1977 • 34 citations

CURRENT STATUS OF MENOPAUSE AND POSTMENOPAUSAL ESTROGEN THERAPY

1977 • 34 citations

The Menopause : comprehensive management

1980 • 33 citations

Metabolic and hormonal effects of post-menopausal oestrogen replacement treatment. I. Glucose, insulin and human growth hormone levels during oral glucose tolerance tests.

1977 • 33 citations

Effect of natural oestrogens on blood pressure and weight in postmenopausal women.

1975 • 32 citations

ESTROGENS AND ATHEROSCLEROSIS

1976 • 32 citations

Hyperplasia of the endometrium.

1953 • 30 citations

METABOLIC AND HORMONAL EFFECTS OF POST-MENOPAUSAL OESTROGEN REPLACEMENT TREATMENT

1977 • 29 citations

The effect of estriol succinate therapy on plasma renin activity and urinary aldosterone in postmenopausal women

1978 • 27 citations

Definitive Symptoms of Post-Menopause � Incorporating Use of Vaginal Parabasal Cell Index

2015 • 26 citations

Estrogen and the Postmenopausal Breast

1978 • 26 citations

AGE, ESTROGENS, AND THE PSYCHE

1981 • 25 citations

Endometrial carcinoma: The effect of estrogens

1979 • 25 citations

ON THE NATURE OF THE HOT FLASH

1981 • 24 citations

Differential Biological Activity of Estradiol Metabolites

1978 • 24 citations

THE COMPARATIVE EFFECTS OF A SYNTHETIC AND A‘NATURAL’ OESTROGEN ON THE HAEMOSTATIC MECHANISM IN PATIENTS WITH PRIMARY AMENORRHOEA

1978 • 23 citations

Estrogen Therapy and Breast Cancer in Postmenopausal Women†

1980 • 23 citations

THE RELIEF OF MENOPAUSE SYMPTOMS BY ESTROGENIC PREPARATIONS

1935 • 22 citations

Evaluation of Equilin 3-Monosulfate and Other Estrogens

1971 • 22 citations

Benign breast disease in women on estrogen therapy.A pathologic study

1972 • 20 citations

THE EFFECT OF TREATMENT WITH OESTRADIOL AND OESTRIOL ON FASTING SERUM CHOLESTEROL AND TRIGLYCERIDE LEVELS IN POSTMENOPAUSAL WOMEN

1977 • 19 citations

The effect of conjugated estrogens on coagulability in menopausal women.

1977 • 18 citations

Conjugated Estrogens Bioinequivalence: Comparison of Four Products in Postmenopausal Women

1979 • 17 citations

ESTROGENIC STATUS OF MENSTRUATING AND MENOPAUSAL WOMEN ASSESSED BY CERVICOVAGINAL SMEARS

1971 • 17 citations

Comparative Studies of the Ethynyl Estrogens used in Oral Contraceptives. VI. Effects with and without Progestational Agents on Carbohydrate Metabolism in Humans, Baboons, and Beagles

1978 • 17 citations

Metabolic Effects of Oestrogen Treatment in Patients with Carcinoma of Prostate: A Comparison of Stilboestrol and Conjugated Equine Oestrogens

1973 • 15 citations

Suppression of ovulation by trip-anisyl chloroethylene (TACE).

1956 • 15 citations

Metabolic effect of conjugated oestrogens (USP) on glucose tolerance.

1974 • 15 citations

THE FEMALE CLIMACTERIC SYNDROME: SIGNIFICANCE, PROBLEMS, TREATMENT

1975 • 15 citations

TUMORIGENIC POWERS OF STILBŒSTROL AND FOLLICULAR HORMONES

1940 • 15 citations

Natural estrogen and anti-thrombin III activity in postmenopausal women.

1976 • 14 citations

The Effects of Conjugated Estrogens on Gonadotropins

1980 • 11 citations

The Role of Psychiatry in the Menopause

1977 • 11 citations

Pharmacology of natural and synthetic estrogens

1976 • 11 citations

Blood Pressure and Estrogens

2015 • 10 citations

ASSESSMENT OF ESTROGEN AND PROGESTIN THERAPY IN GYNECOLOGY AND OBSTETRICS

1977 • 9 citations

Do natural estrogens pose an increased risk of thrombosis in postmenopausal women?

1978 • 8 citations

Chromosome Pattern in a Patient with Cervical Carcinoma in situ and Atypical Hyperplasia of the Endometrium

1972 • 8 citations

Clinical significance of estrogen metabolism and physiology.

1978 • 8 citations

Estrogen Receptor Binding and Growth of the Reproductive Tract

1978 • 7 citations

Frequency and severity of menopausal symptoms

1976 • 7 citations

The Heritable Hyperlipoproteinemias and Atherosclerosis

1975 • 6 citations

Rheumatology as a Whole-time Specialty

1958 • 6 citations

Effects and Side-effects of Estrogen Therapy

1976 • 6 citations

ESTROGENS AND THROMBOEMBOLIC DISEASES

1976 • 5 citations

Gynecologic problems of menopausal women: Part 3. Changes in extragenital tissues and sexuality.

1978 • 5 citations

ESTROGEN RECEPTORS

1976 • 3 citations

Treatment of osteoporosis.

1978 • 3 citations

Polarization of Attitudes

1975 • 2 citations

Diagnosis and Control of Infection

1974 • 1 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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