von Willebrand factor bound to glycoprotein Ib is cleared from the platelet surface after platelet activation by thrombin

Studies with a murine monoclonal antibody that abolishes ristocetin- induced binding of von Willebrand factor to platelets: additional evidence in support of GPIb as a platelet receptor for von Willebrand factor

1983 • 469 citations

Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery.

1986 • 457 citations

von Willebrand factor and von Willebrand disease [published erratum appears in Blood 1988 Mar;71(3):830]

1987 • 435 citations

Molecular Defects in Interactions of Platelets with the Vessel Wall

1984 • 381 citations

von Willebrand factor and von Willebrand disease [published erratum appears in Blood 1988 Mar;71(3):830]

1987 • 311 citations

The von Willebrand factor-binding domain of platelet membrane glycoprotein Ib. Characterization by monoclonal antibodies and partial amino acid sequence analysis of proteolytic fragments.

1986 • 238 citations

Redistribution of alpha-granules and their contents in thrombin-stimulated platelets.

1984 • 205 citations

An enhanced method for post-embedding immunocytochemical staining which preserves cell membranes.

1990 • 199 citations

Substructure of human von Willebrand factor.

1985 • 198 citations

Resting platelets contain a substantial centrally located pool of glycoprotein IIb-IIIa complex which may be accessible to some but not other extracellular proteins.

1986 • 191 citations

Glycoprotein Ib and glycoprotein IX are fully complexed in the intact platelet membrane

1987 • 191 citations

Thrombin-induced exposure and prostacyclin inhibition of the receptor for factor VIII/von Willebrand factor on human platelets.

1982 • 190 citations

Diagnosis of Bernard-Soulier syndrome and Glanzmann's thrombasthenia with a monoclonal assay on whole blood.

1983 • 185 citations

Identification of a site in the alpha chain of platelet glycoprotein Ib that participates in von Willebrand factor binding.

1990 • 182 citations

Calcium regulation of the platelet membrane glycoprotein IIb-IIIa complex.

1985 • 178 citations

Structure-function relationship of human von Willebrand factor

1987 • 164 citations

Immunological study of in vitro maturation of human megakaryocytes

1984 • 162 citations

Ristocetin-dependent reconstitution of binding of von Willebrand factor to purified human platelet membrane glycoprotein Ib-IX complex

1988 • 157 citations

Thrombin induces a rapid redistribution of glycoprotein Ib-IX complexes within the membrane systems of activated human platelets

1990 • 154 citations

Eccentric localization of von Willebrand factor in an internal structure of platelet alpha-granule resembling that of Weibel-Palade bodies

1985 • 150 citations

Thrombin-induced changes in platelet membrane glycoproteins Ib, IX, and IIb-IIIa complex

1987 • 124 citations

Role of botrocetin in platelet agglutination: formation of an activated complex of botrocetin and von Willebrand factor

1989 • 124 citations

Human von Willebrand factor: a multivalent protein composed of identical subunits

1986 • 120 citations

Effect of multimeric structure of the factor VIII/von Willebrand factor protein on binding to platelets

1981 • 115 citations

Interaction of purified type IIB von Willebrand factor with the platelet membrane glycoprotein Ib induces fibrinogen binding to the glycoprotein IIb/IIIa complex and initiates aggregation.

1985 • 106 citations

Functional domains on von Willebrand factor. Recognition of discrete tryptic fragments by monoclonal antibodies that inhibit interaction of von Willebrand factor with platelets and with collagen.

1984 • 101 citations

The surface-connected canalicular system of blood platelets--a fenestrated membrane system.

1980 • 101 citations

Asialo von Willebrand factor interactions with platelets. Interdependence of glycoproteins Ib and IIb/IIIa for binding and aggregation.

1985 • 93 citations

Studies on the Mechanism of Ristocetin-Induced Platelet Agglutination

1977 • 84 citations

von Willebrand protein facilitates platelet incorporation in polymerizing fibrin.

1986 • 84 citations

Immunofluorescent localization of adhesive glycoproteins in resting and thrombin-stimulated platelets.

1984 • 82 citations

Endocytosis by human platelets: metabolic and freeze-fracture studies.

1981 • 78 citations

Inhibition of von Willebrand factor–platelet interaction by fibrinogen

1984 • 72 citations

Uptake of latex particles by blood platelets: phagocytosis or sequestration?

1972 • 69 citations

Identification of platelet glycoprotein IIb/IIIa as the major binding site for released platelet-von Willebrand factor [published erratum appears in Blood 1987 Jun;69(6):1789]

1986 • 67 citations

Immunocytochemical study of the binding of fibrinogen and thrombospondin to ADP- and thrombin-stimulated human platelets

1985 • 66 citations

Electron microscopy of human factor VIII/Von Willebrand glycoprotein: effect of reducing reagents on structure and function.

1982 • 64 citations

Thrombin decreases von Willebrand factor binding to platelet glycoprotein Ib

1988 • 57 citations

Identification of platelet glycoprotein IIb/IIIa as the major binding site for released platelet-von Willebrand factor [published erratum appears in Blood 1987 Jun;69(6):1789]

1986 • 51 citations

Receptor–ligand complexes are cleared to the open canalicular system of surface‐activated platelets

1990 • 48 citations

Type IIB von Willebrand factor with normal sialic acid content induces platelet aggregation in the absence of ristocetin. Role of platelet activation, fibrinogen, and two distinct membrane receptors.

1987 • 46 citations

Distinct abnormalities in the interaction of purified types IIA and IIB von Willebrand factor with the two platelet binding sites, glycoprotein complexes Ib-IX and IIb-IIIa.

1990 • 44 citations

The influence of haemaccel, fibrinogen and albumin on ristocetin-induced platelet aggregation. Relevance to the quantitative measurement of the ristocetin cofactor

1976 • 39 citations

Duplication of a methionine within the glycoprotein Ib binding domain of von Willebrand factor detected by denaturing gradient gel electrophoresis in a patient with type IIB von Willebrand disease

1991 • 38 citations

Surface membrane clearing of receptor–ligand complexes in human blood platelets

1987 • 32 citations

Platelet membrane responses to surface and suspension activation.

1990 • 28 citations

von Willebrand factor is present on the surface of platelets stimulated in plasma by ADP

1987 • 27 citations

Effect of calcium ion concentration on the ability of fibrinogen and von Willebrand factor to support the ADP-induced aggregation of human platelets

1987 • 23 citations

Effect of aspirin on platelet-von Willebrand factor surface expression on thrombin and ADP-stimulated platelets

1989 • 18 citations

Ristocetin induces platelet aggregation: a morphological demonstration

1988 • 15 citations

Localization of surface vWF on resting and stimulated platelets

1987 • 12 citations

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