The Role of Interferon-α in the Management of Myelomatosis

Virus interference. I. The interferon

1957 • 3,331 citations

Leukocyte Interferon-Induced Tumor Regression in Human Metastatic Breast Cancer, Multiple Myeloma, and Malignant Lymphoma

1980 • 503 citations

Maintenance Treatment with Recombinant Interferon Alfa-2b in Patients with Multiple Myeloma Responding to Conventional Induction Chemotherapy

1990 • 389 citations

Purified human immune interferon has more potent anticellular activity than fibroblast or leukocyte interferon

1980 • 221 citations

Comparative antiproliferative activity in vitro of natural interferons alpha and beta for diploid and transformed human cells.

1982 • 188 citations

Role of G0-G1 arrest in the inhibition of tumor cell growth by interferon.

1980 • 173 citations

INTERFERONS

1989 • 153 citations

Induction and kinetics of natural killer cells in humans following interferon therapy

1979 • 152 citations

Interactions of human leukocyte interferon with vinca alkaloids and other chemotherapeutic agents against human tumors in clonogenic assay

1983 • 147 citations

Combined recombinant human interferon alpha₂ and cytotoxic agents studied in a clonogenic assay

1985 • 136 citations

Positive interactions between human interferon and cyclophosphamide or adriamycin in a human tumor model system.

1984 • 136 citations

Treatment of multiple myeloma with recombinant alpha-interferon

1986 • 129 citations

Effects of cloned human leukocyte interferons in the human tumor stem cell assay.

1983 • 127 citations

Phase II study of recombinant alpha-2 interferon in resistant multiple myeloma.

1985 • 108 citations

Biochemical pathways in interferon-action

1984 • 96 citations

REAPPRAISAL OF PLATEAU PHASE IN MYELOMA

1980 • 94 citations

Recombinant interferons increase macrophage Fc receptor capacity.

1984 • 85 citations

How does interferon inhibit tumor growth?

1985 • 71 citations

Immunomodulation by interferons: recent developments.

1985 • 69 citations

Human leukocyte interferon and intermittent high-dose melphalan-prednisone administration in the treatment of multiple myeloma: a randomized clinical trial from the Myeloma Group of Central Sweden.

1984 • 68 citations

Noncycling Tumor Cells Are Sensitive Targets for the Antiproliferative Activity of Human Interferon

1979 • 67 citations

Interferon and natural killer activity in multiple myeloma. Lack of correlation between interferon‐induced enhancement of natural killer activity and clinical response to human interferon‐α

1982 • 63 citations

Correlation between in vitro and in vivo sensitivity to human leucocyte interferon in patients with multiple myeloma

1985 • 61 citations

Interferon Treatment For Multiple Myeloma

1982 • 53 citations

ROLE OF INTERFERON‐INDUCED ENZYMES IN THE ANTIVIRAL AND ANTIMITOGENIC EFFECTS OF INTERFERON

1980 • 50 citations

Interferon nomenclature.

1980 • 49 citations

High doses of natural α‐interferon (α‐IFN) in the treatment of multiple myeloma — A pilot study from the Myeloma Group of Central Sweden (MGCS)

1988 • 48 citations

Clinical Results of Leukocyte Interferon-Induced Tumor Regression in Resistant Human Metastatic Cancer Resistant to Chemotherapy and/or Radiotherapy-Pulse Therapy Schedule

1985 • 47 citations

Recombinant interferon‐ γ inhibits the growth of IL‐6‐dependent human multiple myeloma cell lines in vitro

1991 • 46 citations

The in vitro effect of leucocyte α‐interferon on human myeloma cells in a semisolid agar culture system

1985 • 46 citations

Alpha‐2a‐interferon/melphalan/prednisone versus melphalan/prednisone in previously untreated patients with multiple myeloma

1990 • 46 citations

Interferon Therapy in Multiple Myeloma

1979 • 45 citations

Recombinant interferon alfa-2C versus polychemotherapy (VMCP) for treatment of multiple myeloma: a prospective randomized trial

1986 • 45 citations

Alpha-2-interferon/melphalan/prednisone in previously untreated patients with multiple myeloma: a phase I-II trial.

1986 • 44 citations

Sensitive inhibitory effect of interferon-alpha on M-protein secretion of human myeloma cells

1989 • 37 citations

Autocrine interferon and the suppression of the c-myc nuclear oncogene.

1987 • 36 citations

Development of transformed phenotype induced by a human ras oncogene is inhibited by interferon

1985 • 33 citations

α-Interferon Combination Therapy of Resistant Myeloma

1991 • 26 citations

Phase II study of rDNA human alpha-2 interferon in multiple myeloma.

1985 • 25 citations

Combination of interferon and dexamethasone in refractory multiple myeloma

1990 • 22 citations

Mechanism of interferon action

1985 • 16 citations

Influence of interferon on antibody production and viability of malignant cells from patients with multiple myeloma

1991 • 15 citations

Interferon therapy during the plateau phase of multiple myeloma: An update of the Swedish study

1991 • 15 citations

Alpha interferon raises serum beta‐2‐microglobulin in patients with multiple myeloma

1991 • 7 citations

Phase II study of human lymphoblastoid interferon in patients with multiple myeloma.

1988 • 6 citations

Effect of interferon alpha‐2b in advanced multiple myeloma

1990 • 5 citations