Sustained high levels of circulating chaperoned interleukin-6 after active specific cancer immunotherapy

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Interleukin-6 is a potent thrombopoietic factor in vivo in mice

1989 • 422 citations

B cell stimulatory factor-2 is involved in the differentiation of cytotoxic T lymphocytes.

1988 • 382 citations

Human high molecular weight melanoma-associated antigen (HMW-MAA) mimicry by mouse anti-idiotypic monoclonal antibody MK2-23: induction of humoral anti-HMW-MAA immunity and prolongation of survival in patients with stage IV melanoma.

1992 • 261 citations

Phase I trial of subcutaneous interleukin-6 in patients with advanced malignancies.

1993 • 223 citations

Characterization of IL-6 receptor expression by monoclonal and polyclonal antibodies.

1989 • 179 citations

Cytokines in normal and abnormal parturition: Elevated amniotic fluid interleukin-6 levels in women with premature rupture of membranes associated with intrauterine infection

1991 • 157 citations

Role of interleukin-6 in regulating synthesis of C-reactive protein and serum amyloid A in human hepatoma cell lines

1988 • 156 citations

Stimulation of thrombopoiesis in mice by human recombinant interleukin 6.

1990 • 151 citations

High levels of “complexed” interleukin-6 in human blood.

1992 • 133 citations

Antibodies chaperone circulating IL-6. Paradoxical effects of anti-IL-6 "neutralizing" antibodies in vivo.

1993 • 108 citations

Modulation by adjuvants and carriers of the immunogenicity in xenogeneic hosts of mouse anti-idiotypic monoclonal antibody MK2-23, an internal image of human high molecular weight-melanoma associated antigen.

1993 • 30 citations

Comparison of three immunoassays for C-reactive protein determination.

1985 • 9 citations