Dendritic cells of the oral mucosa and the induction of oral tolerance. A local affair.

Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4, and prostaglandin E expression in the brain.

1992 • 726 citations

Localization of antigen on lymph node dendritic cells after exposure to the contact sensitizer fluorescein isothiocyanate. Functional and morphological studies.

1987 • 592 citations

Evidence that cutaneous antigen-presenting cells migrate to regional lymph nodes during contact sensitization.

1990 • 543 citations

A shared alloantigenic determinant on Ia antigens encoded by the I-A and I-E subregions: evidence for I region gene duplication.

1981 • 531 citations

Regulation of murine lymphokine production in vivo. III. The lymphoid tissue microenvironment exerts regulatory influences over T helper cell function.

1990 • 349 citations

Inhibition of T cell and antibody responses to house dust mite allergen by inhalation of the dominant T cell epitope in naive and sensitized mice.

1993 • 334 citations

Antigen acquisition by dendritic cells: intestinal dendritic cells acquire antigen administered orally and can prime naive T cells in vivo.

1993 • 284 citations

Direct evidence for anergy in T lymphocytes tolerized by oral administration of ovalbumin

1993 • 233 citations

Reduced frequency of nickel allergy upon oral nickel contact at an early age

1991 • 170 citations

The role of dendritic cells in the initiation of immune responses to contact sensitizers

1985 • 146 citations

Inhibition of specific immune responses by feeding protein antigens. IV. Evidence for tolerance and specific active suppression of cell-mediated immune responses to ovalbumin.

1979 • 131 citations

Dermal and intravascular Langerhans cells at sites of passively induced allergic contact sensitivity

1975 • 123 citations

Dendritic Cell Accumulation in Draining Lymph Nodes during the Induction Phase of Contact Allergy in Mice

1989 • 92 citations

Immunologic tolerance after oral administration of reovirus: requirement for two viral gene products for tolerance induction.

1981 • 70 citations

Persistent Immune Tolerance to Nickel and Chromium by Oral Administration Prior to Cutaneous Sensitization

1992 • 70 citations

Sublingual allergen administration. I. Selective suppression of IgE production in rats by high allergen doses

1988 • 58 citations

Immunosuppression caused by antigen feeding II. Suppressor T cells mask Peyer's patch B cell priming to orally administered antigen

1983 • 56 citations

Orally induced tolerance generates an efferently acting suppressor T cell and an acceptor T cell that together down-regulate contact sensitivity.

1985 • 51 citations

Oral administration of the contact sensitizer trinitrochlorobenzene: Initial sensitization and subsequent appearance of a suppressor population

1990 • 35 citations

Suppressor T cells, antigen-presenting cells and the role of I-J restriction in oral tolerance to ovalbumin.

1988 • 32 citations

Age-associated changes in Langerhans cells of murine oral epithelium and epidermis

1987 • 30 citations

The phenotype of murine Langerhans cells from skin to lymph node.

1993 • 10 citations