Demonstration of separate binding sites for the folate coenzymes and deoxynucleotides with inactivated Lactobacilluscasei thymidylate synthetase

Methods in Enzymology , Vol

1966 • 26,261 citations

Crystalline Dihydropteroylglutamic Acid

1960 • 461 citations

The Stability of N-Ethylmaleimide and its Reaction with Sulfhydryl Groups

1955 • 340 citations

Thymidylate synthetase from amethopterin- resistant Lactobacillus casei

1971 • 228 citations

Solid-phase synthesis of polyglutamates of folic acid

1969 • 185 citations

Fluorinated pyrimidines. Structures of reversible and irreversible complexes of thymidylate synthetase and fluorinated pyrimidine nucleotides

1974 • 172 citations

Polyglutamyl Derivatives of Folate as Substrates and Inhibitors of Thymidylate Synthetase

1974 • 145 citations

Enzymic Preparation of the l,l-Diastereoisomer of Tetrahydrofolic Acid

1960 • 125 citations

Factors affecting substrate binding in Lactobacillus casei thymidylate synthetase as studied by equilibrium dialysis

1976 • 112 citations

Studies on γ-glutamyl carboxypeptidase I. The solid phase synthesis of analogs of polyglutamates of folic acid and their effects on human liver γ-glutamyl carboxypeptidase

1970 • 83 citations

Interaction of deoxyuridylate with thymidylate synthetase.

1975 • 80 citations

Identification of poly-γ-glutamyl chain lengths in bacterial folates

1974 • 62 citations

Effect of substrate analogs on the circular dichroic spectra of thymidylate synthetase from Lactobacillus casei

1975 • 54 citations

Formation of ternary complexes of thymidylate synthetase as followed by absorbance, fluorescence, and circular dichroic spectra and gel electrophoresis.

1976 • 47 citations

The Carboxypeptidase-dependent Inactivation of Thymidylate Synthetase

1974 • 39 citations

Characterization of the subunits of thymidylate synthetase

1972 • 29 citations