Pathogenesis and Pathophysiology of Duodenal Ulcer

Live Events, Stress, and Illness

1976 • 1,325 citations

Gastric Acid Secretion Rate and Buffer Content of the Stomach after Eating. RESULTS IN NORMAL SUBJECTS AND IN PATIENTS WITH DUODENAL ULCER

1973 • 451 citations

Association of Adrenocorticosteroid Therapy and Peptic-Ulcer Disease

1983 • 429 citations

The Blood Groups in Relation to Peptic Ulceration and Carcinoma of Colon, Rectum, Breast, and Bronchus

1954 • 428 citations

The relationship between the acid output of the stomach following "maximal" histamine stimulation and the parietal cell mass.

1960 • 426 citations

Nonassociation of Adrenocorticosteroid Therapy and Peptic Ulcer

1976 • 357 citations

Experiments AND Observations ON THE Gastric Juice AND THE Physiology OF Digestion.

1929 • 349 citations

pH dependence of acid secretion and gastrin release in normal and ulcer subjects.

1975 • 330 citations

Cigarettes, Alcohol, Coffee and Peptic Ulcer

1974 • 278 citations

Healing of duodenal ulcer with an antacid regimen

1978 • 269 citations

ABO Blood Groups and Secretor Character in Duodenal Ulcer

1956 • 230 citations

Basal and Histalog-Stimulated Gastric Secretion in Control Subjects and in Patients with Peptic Ulcer or Gastric Cancer

1963 • 208 citations

Stomach size and its relation to chronic peptic ulcer.

1952 • 195 citations

Cellular localisation of human urogastrone/epidermal growth factor

1978 • 179 citations

Duodenal-Ulcer Disease Associated with Elevated Serum Pepsinogen I

1979 • 174 citations

MAINTENANCE TREATMENT OF RECURRENT PEPTIC ULCER BY CIMETIDINE

1978 • 170 citations

Influence of Feeding and Sham Feeding upon Serum Gastrin and Gastric Acid Secretion in Control Subjects and Duodenal Ulcer Patients

1974 • 168 citations

Inherited predisposition to generalized amyloidosis

1969 • 167 citations

Gastric Secretion and Emptying after Ordinary Meals in Duodenal Ulcer

1977 • 166 citations

Trends in hospital admissions and death rates for peptic ulcer in the United States from 1970 to 1978

1980 • 163 citations

Increased sensitivity to stimulation of acid secretion by pentagastrin in duodenal ulcer.

1975 • 161 citations

Effect of gastrointestinal intubation on the passage of a solid meal through the stomach and small intestine in humans

1983 • 156 citations

[Physiology of gastric secretion].

1968 • 140 citations

PEPTIC ULCERATION IN CHRONIC RENAL FAILURE

1973 • 137 citations

USE OF PENTAGASTRIN IN A TEST OF GASTRIC ACID SECRETION

1967 • 126 citations

Comparison of maximal acid output and gastrin response to meals in Chinese and Scottish normal and duodenal ulcer subjects.

1980 • 126 citations

Stressful Life Events, Acid Hypersecretion, and Ulcer Disease

1983 • 123 citations

Influence of smoking on healing rate of duodenal ulcer in response to cimetidine or high-dose antacid

1981 • 122 citations

Treatment of duodenal ulcer with antacid and sulpiride. A double-blind controlled study.

1979 • 121 citations

Gastric Acid Secretion is Abnormally Sensitive to Endogenous Gastrin Released after Peptone Test Meals in Duodenal Ulcer Patients

1980 • 116 citations

The Incidence of Duodenal Ulcer in Copenhagen County

1975 • 115 citations

An assessment of the augmented histamine test in the diagnosis of peptic ulcer: Correlations between gastric secretion, age and sex of patients, and site and nature of the ulcer

1963 • 113 citations

Duodenal ulcer in black populations in Africa south of the Sahara.

1975 • 111 citations

Gastric mucosal blood distribution and its changes in the healing process of gastric ulcer

1983 • 111 citations

Stilboestrol, Phenobarbitone, and Diet in Chronic Duodenal Ulcer

1960 • 109 citations

Analgesic ingestion and chronic peptic ulcer

1981 • 109 citations

Causes of peptic ulcer

1967 • 106 citations

Simultaneous Measurement of Basal Pancreatic, Gastric Acid Secretion, Plasma Gastrin, and Secretin During Smoking

1977 • 104 citations

Treatment of duodenal ulcer with antacid and sulpiride

1979 • 103 citations

A Concept of the Etiology of Gastric and Duodenal Ulcers

1956 • 91 citations

GASTRIC AND DUODENAL ULCER AND THEIR ASSOCIATED DISEASES

1976 • 86 citations

Distribution of prostaglandins in gastric and duodenal mucosa of healthy subjects and duodenal ulcer patients: effects of aspirin and paracetamol.

1981 • 86 citations

Peptic ulcer disease--a heterogeneous group of disorders?

1977 • 82 citations

Randomised crossover trial of tripotassium dicitrato bismuthate versus high dose cimetidine for duodenal ulcers resistant to standard dose of cimetidine.

1984 • 79 citations

Acidity at different sites in the proximal duodenum of normal subjects and patients with duodenal ulcer.

1966 • 78 citations

Selective Coating of Gastric Ulcer by Tripotassium Dicitrato Bismuthate in the Rat

1982 • 78 citations

Gastric emptying in control subjects and patients with duodenal ulcer before and after vagotomy.

1976 • 75 citations

HEREDITARY FACTORS IN PEPTIC ULCER

1949 • 75 citations

Chronic Gastritis: Its Relation to Gastric and Duodenal Ulcer and to Gastric Carcinoma.

1943 • 75 citations

Gastrointestinal involvement in systemic mastocytosis.

1976 • 74 citations

Peptic Ulcer Disease-A Heterogeneous Group of Disorders?

1977 • 73 citations

Accurate prediction of duodenal-ulcer healing rate by discriminant analysis

1983 • 71 citations

Advances in ulcer disease

1981 • 67 citations

Causes of Death in Duodenal and Gastric Ulcer

1977 • 66 citations

A comparative study of the effects of gastrin, histamine, histalog, and mechothane on the secretory capacity of the human stomach in two normal subjects over 20 months.

1965 • 66 citations

Family Studies of Hypergastrinemic, Hyperpepsinogenemic I Duodenal Ulcer

1981 • 65 citations

Trends in hospital admission, perforation, and mortality of peptic ulcer in Hong Kong from 1970 to 1980

1983 • 64 citations

Duodenal pH values in normal controls and in patients with duodenal ulcer.

1969 • 64 citations

Acid-Base Parameters of Duodenal Contents in Man

1972 • 63 citations

A Simple Measure of Gastric Secretion in Man

1951 • 63 citations

Factors affecting the healing rate of duodenal and pyloric ulcers with low-dose antacid treatment.

1981 • 63 citations

Effect of sham feeding on gastric acid secretion in healthy subjects and duodenal ulcer patients: Evidence for increased basal vagal tone in some ulcer patients

1980 • 63 citations

Gastric Acid Secretion in Patients Undergoing Chronic Dialysis

1967 • 62 citations

Maximum acid output to graded doses of pentagastrin and its relation to parietal cell mass in Chinese patients with duodenal ulcer.

1977 • 60 citations

Effect of Selective Proximal Vagotomy on Food-Stimulated Gastric Acid Secretion and Gastrin Release in Patients With Duodenal Ulcer

1979 • 58 citations

In Situ ph of Duodenal Bulb Contents in Normal and Duodenal Ulcer Subjects

1967 • 58 citations

Life events and chronic duodenal ulcer: a case control study

1981 • 57 citations

Gastric pepsin and acid secretion in patients with acute and healed duodenal ulcer

1981 • 56 citations

Rapid gastric emptying in duodenal ulcer patients

1982 • 52 citations

The relationship between basal and maximum acid output in normal subjects and patients with duodenal ulcer.

1963 • 51 citations

Smoking And Duodenal Ulcer

1978 • 51 citations

Serial pH Changes in the Duodenal Bulb During Smoking

1978 • 50 citations

A comparison of the nocturnal gastric secretion in patients with duodenal ulcer and in normal individuals.

1968 • 50 citations

Effect of Graded Amounts of Acid Instilled into the Duodenum on Pancreatic Bicarbonate Secretion and Plasma Secretin in Duodenal Ulcer Patients and Normal Subjects

1977 • 49 citations

Duodenal ulcer disease in the hospitalized elderly patient

1982 • 49 citations

Levels of intragastric and intraduodenal acidity.

1955 • 48 citations

HLA-B5 Associated with Duodenal Ulcer

1977 • 48 citations

Continuously Recorded in Situ pH of Gastric and Duodenal Contents in Patients with and Without Duodenal Ulcers

1956 • 48 citations

Duodenal ulcers: early and late onset.

1976 • 48 citations

The Relation between Functioning Parietal Cell and Gastrin Cell Masses in Two Groups of Duodenal Ulcer Patients

1976 • 47 citations

Modern Trends in Gastroenterology 5

1976 • 46 citations

Progress report. Aspirin in chronic gastric ulcer: an Australian experience.

1976 • 46 citations

Pachydermoperiostosis, hypertrophic gastropathy, and peptic ulcer

1983 • 45 citations

Genetics and heterogeneity of common gastrointestinal disorders

1981 • 44 citations

Basal gastric secretion: reproducibility and relationship with duodenal ulceration.

1977 • 43 citations

Duodenal ulcer with unexplained marked basal gastric acid hypersecretion

1980 • 43 citations

Gastric and Extragastric Gastrin Release in Normal Subjects, in Duodenal Ulcer Patients, and in Patients With Partial Gastrectomy (Billroth I)

1976 • 43 citations

Studies with the maximal histamine test.

1965 • 41 citations

The Clinical Application of Gastric Secretion Measurements

1973 • 41 citations

One hundred and sixty-nine studies in gastric secretion during the night

1934 • 40 citations

Pentagastrin Dose-Response in Peptic Ulcer Disease

1975 • 38 citations

Gastric Acid Secretion and Sleep Stages During Natural Night Sleep

1975 • 35 citations

Studies on Duodenal Ulcer<xref ref-type="fn" rid="fn1"><sup>1</sup></xref><subtitle>1. THE CLINICAL EVIDENCE FOE THE EXISTENCE OF TWO POPULATIONS</subtitle>

1975 • 35 citations

Gastric acid secretion in Indians with particular reference to the ratio of basal to maximal acid output.

1966 • 34 citations

BASAL GASTRIC SECRETION AS A CLINICAL TEST OF GASTRIC FUNCTION WITH SPECIAL REFERENCE TO PEPTIC ULCER

1940 • 34 citations

Association between duodenal bulb ulceration and reduced exocrine pancreatic function.

1983 • 33 citations

Gastric acid secretion in Chinese with particular reference to the dose of histamine required for maximal stimulation

1970 • 31 citations

The Measurement of Gastric Acid

1965 • 30 citations

Basal Gastric Secretion in Patients with Duodenal Ulcer: A Long Term Study of Variations in Relation to Ulcer Activity

1962 • 28 citations

Abnormalities of acid secretion in patients with duodenal ulcer

1978 • 28 citations

Gastric function and histology in chronic renal failure.

1979 • 28 citations

HYDROGEN ION CONCENTRATION OF THE DUODENAL CONTENTS UNDER FASTING CONDITIONS IN NORMAL PERSONS AND IN PATIENTS WITH DUODENAL ULCER: A COMPARATIVE STUDY 1

1941 • 27 citations

Gastric mucosal histamine and histamine methytltransferase in patients with duodenal ulcer.

1982 • 27 citations

PRESENT STATUS OF HISTALOG GASTRIC ANALYSIS IN MAN*

1967 • 27 citations

An Apparent Exception to Schwarz’s Dictum, “No Acid — No Ulcer”

1971 • 27 citations

HLA and duodenal ulcer.

1979 • 26 citations

Twelve-hour Nocturnal Gastric Secretion in Uncomplicated Duodenal Ulcer Patients: Before and After Healing

1948 • 26 citations

Relationship of postprandial serum gastrin response to sex, body weight, blood group status, familial dyspepsia, duration, and age of onset of ulcer symptoms in duodenal ulcer.

1980 • 25 citations

Eight-year experience with 3392 endoscopically proven duodenal ulcers in Durban, 1972-79. Rise and fall of duodenal ulcers and a theory of changing dietary and social factors.

1981 • 25 citations

Peptic Ulcer and Chronic Obstructive Bronchopulmonary Disease

1964 • 24 citations

MAXIMUM ACID OUTPUT AND POSITION OF PEPTIC ULCERS

1976 • 23 citations

Duodenal Ulcer as a Second Disease

1970 • 22 citations

Early- and Late-Onset Duodenal Ulcers in Chinese and Scots

1983 • 21 citations

Antral activity and symptom periodicity in duodenal ulceration.

1967 • 21 citations

Identification of Two Subgroups of Familial Early-Onset Duodenal Ulcers

1980 • 21 citations

Food-Stimulated Acid Secretion Measured by Intragastric Titration with Bicarbonate in Patients with Duodenal and Gastric Ulcer Disease and in Controls

1978 • 21 citations

Essential tremor, nystagmus and duodenal ulceration: A “new” dominantly inherited condition*

1976 • 20 citations

A Comparison of the Acid and Gastrin Secretory Responses to Hypoglycaemia and Meals in Duodenal Ulcer With and Without Acid Hypersecretion to Pentagastrin

1976 • 20 citations

The Continuous Twelve-Hour Nocturnal Gastric Secretion in Normal Individuals and in Patients With Duodenal Ulcer After a 24-Hour Fast

1950 • 19 citations

Stomach damage from aspirin, steroids and antimetabolites

1962 • 18 citations

The Association of Diffuse Obstructive Pulmonary Emphysema and Chronic Gastroduodenal Ulceration

1962 • 18 citations

Dose of histamine for maximal stimulation of gastric acid secretion. Modified subcutaneous histamine test.

1969 • 18 citations

Sensitivity of the Parietal Cell to Pentagastrin in Health and Duodenal Ulcer Disease: A Reappraisal

1982 • 17 citations

Dose of Histamine for Maximal Stimulation of Gastric Acid Secretion

1969 • 16 citations

HLA and peptic ulcer

1979 • 16 citations

Gastric acid secretion rate and buffer content of the stomach after a rice- and a wheat-based meal in normal subjects and patients with duodenal ulcer.

1979 • 16 citations

Women and duodenal ulcer.

1981 • 15 citations

A clinical evaluation of the maximal histalog test

1967 • 14 citations

EFFECT OF ULCER ON ACIDITY AND NEUTRALIZING ABILITY IN DUODENAL BULB

1942 • 13 citations

Gastrointestinal hormones

1976 • 13 citations

Physiologic, psychologic and social determinants of psychosomatic disorders.

1960 • 12 citations

Sensitivity of the Oxyntic and Peptic Cells to Pentagastrin in Duodenal Ulcer Patients and Healthy Subjects with Similar Secretory Capacity

1982 • 10 citations

Healing of Duodenal Ulcer with an Antacid Regimen

1977 • 9 citations

Evaluating a new anticonvulsant in a "therapeutic community".

1960 • 7 citations

Complications of Peptic Ulcer Disease in Geriatric Patients*

1973 • 5 citations

Abbreviated Histalog gastric analysis

1967 • 2 citations