Selective Ceramide Binding to Protein Kinase C-α and -δ Isoenzymes in Renal Mesangial Cells

Protein kinase C and lipid signaling for sustained cellular responses

1995 • 2,527 citations

Sphingolipid metabolism and cell growth regulation

1996 • 709 citations

Ceramide activates heterotrimeric protein phosphatase 2A

1993 • 657 citations

Sphingomyelin turnover induced by vitamin D3 in HL-60 cells

1989 • 629 citations

Ceramide-induced Translocation of Protein Kinase C-δ and -ϵ to the Cytosol

1997 • 178 citations

Stimulation by extracellular ATP and UTP of the mitogen‐activated protein kinase cascade and proliferation of rat renal mesangial cells

1994 • 111 citations

2-(Tributylstannyl)-4-[3-(trifluoromethyl)-3H-diazirin-3-yl]benzyl Alcohol: A Building Block for Photolabeling and Crosslinking Reagents of Very High Specific Radioactivity

1995 • 96 citations

Activation of phospholipase C and prostaglandin synthesis by [arginine]vasopressin in cultures

1984 • 94 citations

Comparison of extracellular ATP and UTP signalling in rat renal mesangial cells. No indications for the involvement of separate purino- and pyrimidino-ceptors

1990 • 90 citations

Possible regulatory functions of protein kinase C-α and -ε isoenzymes in rat renal mesangial cells. Stimulation of prostaglandin synthesis and feedback inhibition of angiotensin II-stimulated phosphoinositide hydrolysis

1991 • 87 citations

Down-regulation of protein kinase C potentiates angiotensin II-stimulated polyphosphoinositide hydrolysis in vascular smooth-muscle cells

1989 • 69 citations

Ceramide is a competitive inhibitor of diacylglycerol kinase in vitro and in intact human leukemia (HL-60) cells.

1992 • 69 citations

Immunocharacterization of δ‐ and ζ‐isoenzymes of protein kinase C in rat renal mesangial cells

1992 • 67 citations

Extracellular ATP and UTP activation of phospholipase D is mediated by protein kinase C‐ε in rat renal mesangial cells

1993 • 54 citations

A role for protein kinase C‐ϵ in angiotensin II stimulation of phospholipase D in rat renal mesangial cells

1993 • 35 citations

Protein kinase C inhibitors potentiate angiotensin II-induced phosphoinositide hydrolysis and intracellular Ca2+ mobilization in renal mesangial cells

1993 • 33 citations

Antipeptide antibodies directed against the C‐terminus of protein kinase Cζ (PKCζ) react with a Ca²⁺‐ and TPA‐sensitive PKC in HT‐29 human intestinal epithelial cells

1994 • 16 citations