Chromosome translocation activates heterogeneously initiated, bipolar transcription of a mouse c-myc gene.

Continuous cultures of fused cells secreting antibody of predefined specificity

1975 • 17,037 citations

Studies on transformation of Escherichia coli with plasmids

1983 • 11,179 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

A catalogue of splice junction sequences

1982 • 3,861 citations

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor

1983 • 2,350 citations

Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis

1981 • 1,611 citations

A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes

1983 • 1,449 citations

Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells.

1982 • 1,424 citations

A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene

1983 • 1,418 citations

In vivo sequence requirements of the SV40 early promoter region

1981 • 1,156 citations

[18] Hybridization of denatured RNA transferred or dotted to nitrocellulose paper

1983 • 1,112 citations

Cell-cycle control of c-myc but not c-ras expression is lost following chemical transformation

1984 • 785 citations

Translocations Among Antibody Genes in Human Cancer

1983 • 736 citations

HMG CoA reductase: A negatively regulated gene with unusual promoter and 5′ untranslated regions

1984 • 523 citations

Translocation and Rearrangements of the c- myc Oncogene Locus in Human Undifferentiated B-Cell Lymphomas

1983 • 514 citations

Translocation, breakage and truncated transcripts of c-myc oncogene in murine plasmacytomas

1983 • 504 citations

Novel myc oncogene RNA from abortive immunoglobulin-gene recombination in mouse plasmacytomas

1982 • 471 citations

Expression and regulation of immunoglobulin heavy chain gene transfected into lymphoid cells.

1983 • 457 citations

Reversible and persistent changes in chromatin structure accompany activation of a glucocorticoid-dependent enhancer element

1984 • 449 citations

Sequence of the murine and human cellular myc oncogenes and two modes of myc transcription resulting from chromosome translocation in B lymphoid tumours.

1983 • 436 citations

Immunoglobulin gene expression in transformed lymphoid cells.

1983 • 400 citations

Murine T lymphomas in which the cellular myc oncogene has been activated by retroviral insertion

1984 • 358 citations

Activation and somatic mutation of the translocated c-myc gene in Burkitt lymphoma cells

1984 • 335 citations

Cellular myc oncogene is altered by chromosome translocation to an immunoglobulin locus in murine plasmacytomas and is rearranged similarly in human Burkitt lymphomas.

1983 • 330 citations

Deletion mapping of DNA regions required for SV40 early region promoter function in vivo.

1982 • 328 citations

Differential Expression of the Translocated and the Untranslocated c- myc Oncogene in Burkitt Lymphoma

1983 • 328 citations

Identification and nucleotide sequence of a human locus homologous to the v-myc oncogene of avian myelocytomatosis virus MC29

1983 • 287 citations

Synthesis of full length cDNAs from four partially purified oviduct mRNAs.

1978 • 279 citations

The distal transcription signals of the herpesvirus tk gene share a common hexanucleotide control sequence

1984 • 272 citations

Immunoglobulin synthesis by lymphoid cells transformed in vitro by Abelson murine leukemia virus

1979 • 243 citations

Transcriptionally active c- myc oncogene is contained within NIARD, a DNA sequence associated with chromosome translocations in B-cell neoplasia

1983 • 236 citations

Multiple Immunoglobulin Heavy-Chain Gene Transcripts in Abelson Murine Leukemia Virus-Transformed Lymphoid Cell Lines

1982 • 228 citations

An improved procedure for utilizing terminal transferase to add homopolymers to the 3′ termini of DNA

1981 • 176 citations

Switch region of immunoglobulin Cμ gene is composed of simple tandem repetitive sequences

1981 • 173 citations

Characterization of productive and sterile transcripts from the immunoglobulin heavy-chain locus: processing of micron and muS mRNA.

1983 • 165 citations

Rapid synthesis of oligodeoxyribonucleotides VII. Solid phase synthesis of oligodeoxyribonucleo-tides by a eontinuous flow phosphotriester method on a kieselguhr-polyamide support

1982 • 137 citations

Translocation of the myc cellular oncogene to the immunoglobulin heavy chain locus in murine plasmacytomas is an imprecise reciprocal exchange

1984 • 128 citations

Transcriptionally active DNA region that rearranges frequently in murine lymphoid tumors.

1982 • 126 citations

A detailed analysis of an HSV-1 early promoter: sequences involved in trans-activation by viral immediate-early gene products are not early-gene specific

1984 • 117 citations

Transcriptional activation of the translocated c-myc oncogene in mouse plasmacytomas: Similar RNA levels in tumor and proliferating normal cells

1984 • 116 citations

Anti-oxazolone hybridomas and the structure of the oxazolone idiotype.

1983 • 114 citations

Gene segments encoding transmembrane carboxyl termini of immunoglobulin γ chains

1981 • 99 citations

Multiple origins of transcription in the 4.5 Kb upstream of the ϵ-globin gene

1983 • 98 citations

Transcription enhancer identified near the human Cμ immunoglobulin heavy chain gene is unavailable to the translocated c-myc gene in a Burkitt lymphoma

1983 • 97 citations

Increased expression of myc-related oncogene mRNA characterizes most BALB/c plasmacytomas induced by pristane or Abelson murine leukemia virus.

1983 • 96 citations

Effect of the 21-bp repeat upstream element on in vitro transcription from the early and late SV40 promoters.

1984 • 87 citations

Transcriptional activation of immunoglobulin α heavy-chain genes by translocation of the c-myc oncogene

1983 • 84 citations

Interchromosomal recombination of the cellular oncogene c-myc with the immunoglobulin heavy chain locus in murine plasmacytomas is a reciprocal exchange.

1983 • 80 citations

Nucleotide-sequence heterogeneity and sequence rearrangements in influenza virus cDNA

1981 • 75 citations

Reciprocal chromosome translocation between c-myc and immunoglobulin γ2b genes

1983 • 69 citations

DNA sequences near the site of reciprocal recombination between a c-myc oncogene and an immunoglobulin switch region.

1983 • 63 citations

A conserved sequence at c-myc oncogene chromosomal translocation breakpoints in plasmacytomas

1984 • 63 citations

Characterization of Productive and Sterile Transcripts from the Immunoglobulin Heavy-Chain Locus: Processing of μ_m and μ_s mRNA

1983 • 63 citations

Immunoglobulin production by murine B-lymphoma cells

1981 • 38 citations

[20] Synthesis of ds-cDNA involving addition of dCMP tails to allow cloning of 5′-terminal mRNA sequences

1983 • 35 citations

Immunoglobulin production and secretion by variant clones of the MOPC 315 mouse myeloma cell line.

1980 • 29 citations