Mechanism of cAMP-induced Ca2+ influx in Dictyostelium: role of phospholipase A2

Genistein, a specific inhibitor of tyrosine-specific protein kinases.

1987 • 3,773 citations

Phospholipase A2 and its zymogen from porcine pancreas. VI. Histidine at the active site of phospholipase A2

1974 • 465 citations

Inhibition of Macrophage Ca2+-independent Phospholipase A2 by Bromoenol Lactone and Trifluoromethyl Ketones

1995 • 401 citations

Suicide inhibition of canine myocardial cytosolic calcium-independent phospholipase A2. Mechanism-based discrimination between calcium-dependent and -independent phospholipases A2.

1991 • 306 citations

MOLECULAR GENETICS OF SIGNAL TRANSDUCTION IN DICTYOSTELIUM

1996 • 261 citations

Phospholipase A2 enzymes: regulation and inhibition

1993 • 253 citations

CYCLIC AMP AND OTHER SIGNALS CONTROLLING CELL DEVELOPMENT AND DIFFERENTIATION IN DICTYOSTELIUM

1987 • 240 citations

Activation of phospholipases A and C in human platelets exposed to epinephrine: role of glycoproteins IIb/IIIa and dual role of epinephrine.

1986 • 229 citations

Characterisation of the second messenger pathway underlying neurite outgrowth stimulated by FGF

1994 • 163 citations

A G-protein beta-subunit is essential for Dictyostelium development.

1993 • 147 citations

Attractant-induced changes and oscillations of the extracellular Ca++ concentration in suspensions of differentiating Dictyostelium cells.

1984 • 143 citations

Prostaglandins, Leukotrienes and lipoxins

1986 • 111 citations

Effects of aristolochic acid on phospholipase A2 activity and arachidonate metabolism of human neutrophils

1989 • 109 citations

Stimulation of Ca2+-activated human platelet phospholipase A2 by diacylglycerol

1987 • 98 citations

A Ca2+ transport system associated with the plasma membrane of Dictyostelium discoideum is activated by different chemoattractant receptors.

1991 • 94 citations

The interaction of phospholipase A2 with phospholipid analogues and inhibitors.

1990 • 79 citations

ATP-driven Ca2+/H+ antiport in acid vesicles from Dictyostelium.

1992 • 69 citations

Strong increase in the tyrosine phosphorylation of actin upon inhibition of oxidative phosphorylation: Correlation with reversible rearrangements in the actin skeleton of Dictyostelium cells

1994 • 68 citations

The surface cyclic AMP receptors, cAR1, cAR2, and cAR3, promote Ca2+ influx in Dictyostelium discoideum by a G alpha 2-independent mechanism.

1993 • 64 citations

Manoalide, a natural sesterterpenoid that inhibits calcium channels.

1987 • 61 citations

Oscillations of Ca+ + concentration during the cell differentiation of Dictyostelium discoideum

1986 • 59 citations

Primary Structure, Expression and Developmental Regulation of a Dictyostelium Calcineurin A Homologue

1996 • 58 citations

Calmidazolium leads to an increase in the cytosolic Ca2+ concentration in Dictyostelium discoideum by induction of Ca2+ release from intracellular stores and influx of extracellular Ca2+

1996 • 54 citations

Inactivation of bee venom phospholipase A2 by manoalide

1987 • 52 citations

Characterisation of an intracellular Ca2+ pump in Dictyostelium

1994 • 49 citations

Transduction of the chemotactic cAMP signal across the plasma membrane ofDictyostelium cells

1995 • 47 citations

The role of calcium in aggregation and development ofDictyostelium

1995 • 46 citations

Biscoclaurine alkaloids inhibit receptor-mediated phospholipase A2 activation probably through uncoupling of a GTP-binding protein from the enzyme in rat peritoneal mast cells

1992 • 46 citations

A high-affinity plasma membrane Ca2+-ATPase in Dictyostelium discoideum: its relation to cAMP-induced Ca2+ fluxes

1987 • 40 citations

The cell density factor CMF regulates the chemoattractant receptor cAR1 in Dictyostelium.

1996 • 39 citations

Introduction of calcium buffers into the cytosol ofDictyostelium discoideumamoebae alters cell morphology and inhibits chemotaxis

1995 • 35 citations

Evidence for two intracellular calcium pools in Dictyostelium: the campinduced calcium influx is directed into a nbd-cland 2,5-di-(tert-butyl)-1,4 hydroquinone-sensitive pool

1993 • 33 citations

A Newly Cloned Phospholipase A2-Activating Protein Elicits Ca2+ Oscillations and Pancreatic Amylase Secretion via Mediation of G Protein β/Phospholipase A2/Arachidonic Acid Cascades

1994 • 29 citations

Dictyostelium discoideum contains a family of calmodulin‐related EF‐hand proteins that are developmentally regulated

1996 • 27 citations

An increase in cytosolic Ca2+ delays cAMP oscillations in Dictyostelium cells

1996 • 16 citations

Stimulation of calcium influx by platelet activating factor in Dictyostelium

1995 • 15 citations

Calmodulin-antagonists inhibit vesicular Ca2+ uptake in Dictyostelium

1996 • 13 citations