Clinical Effects of Purines
Data up to Jan 2025
Total Citations Per Year
Abstract
References (50)
Clinical Evaluation of a New Antimetabolite, 6-Mercaptopurine, in the Treatment of Leukemia and Allied Diseases
1953 • 379 citations
Experimental Nephrotic Syndrome Induced in Rats by Aminonucleoside. Renal Lesions and Body Electrolyte Composition.
1955 • 204 citations
Studies in Chemotherapy. VIII. Methionine and Purine Antagonists and their Relation to the Sulfonamides1
1945 • 192 citations
PYRIMIDINE DERIVATIVES AS ANTAGONISTS OF PTEROYLGLUTAMIC ACID
1948 • 163 citations
The Synthesis and Properties of 6-Chloropurine and Purine1
1954 • 160 citations
THE FATE OF 6‐MERCAPTOPURINE IN MICE
1954 • 153 citations
ANTAGONISTS OF NUCLEIC ACID DERIVATIVES
1951 • 146 citations
6-Mercaptopurine: effects in mouse sarcoma 180 and in normal animals.
1953 • 139 citations
THE CHEMISTRY AND BIOCHEMISTRY OF PURINE ANALOGS
1954 • 134 citations
Purine Metabolism in Tetrahymena and Its Relation to Malignant Cells in Mice
1949 • 128 citations
THE TOXIC EFFECTS OF 6‐MERCAPTOPURINE AND RELATED COMPOUNDS
1954 • 124 citations
STUDIES ON ANALOGS OF PURINES AND PYRIMIDINES
1950 • 122 citations
The effects of the folic acid antagonists and 2,6-diaminopurine on neoplastic disease.With special reference to acute leukemia
1951 • 116 citations
The Effects of Pyrimidines on the Growth of Lactobacillus casei
1945 • 109 citations
THE BIOLOGICAL ACTIVITY OF SUBSTITUTED PURINES
1949 • 100 citations
THE FATE OF 6‐MERCAPTOPURINE IN MAN
1954 • 85 citations
Achromycin: a new antibiotic having trypanocidal properties.
1952 • 80 citations
Preliminary studies on the effect of 2,6-diaminopurine on transplanted mouse leukemia
1949 • 78 citations
THE INCORPORATION OF EXOGENOUS PURINES INTO PENTOSE NUCLEIC ACID BY LACTOBACILLUS CASEI
1952 • 66 citations
EFFECTS OF 6‐MERCAPTOPURINE AND ANALOGS ON EXPERIMENTAL TUMORS
1954 • 65 citations
RESPONSE OF ACUTE LYMPHOCYTIC LEUKEMIAS TO THE PURINE ANTAGONIST 6‐MERCAPTOPURINE
1954 • 57 citations
ON THE RÔLE OF 2,6-DIAMINOPURINE IN THE BIOSYNTHESIS OF NUCLEIC ACID GUANINE
1950 • 54 citations
THE EFFECT OF 6‐MERCAPTOPURINE ON THE RAT FETUS AND ON REPRODUCTION OF THE RAT
1954 • 54 citations
ON THE MECHANISM OF ACTION OF 6‐MERCAPTOPURINE
1954 • 51 citations
MICROBIOLOGICAL EFFECTS OF 6‐MERCAPTOPURINE
1954 • 49 citations
The effect of 8-azaguanine on the growth of carcinoma, sarcoma, osteogenic sarcoma, lymphosarcoma and melanoma in animals.
1950 • 42 citations
Experimental Chemotherapy of Trypanosomiasis
1953 • 40 citations
CLINICAL STUDIES ON 6‐MERCAPTOPURINE
1954 • 38 citations
Further evidence on the mode of action of 8-azaguanine (guanazolo) in tumor inhibition.
1951 • 37 citations
Studies on 2,6-diaminopurine and related substances in cultures of embryonic and sarcomatous rodent tissues
1951 • 36 citations
Studies on 2,6‐diaminopurine and related substances in cultures of embryonic and sarcomatous rodent tissues
1951 • 36 citations
BIOLOGICAL ACTIVITIES OF 6-MERCAPTOPURINE: EFFECTS ON STREPTOCOCCUS FAECALIS
1954 • 34 citations
Unsubstituted purine and its riboside as toxic antimetabolites in mouse tissue cultures
1955 • 30 citations
Studies on the effects of a guanine a analog on acute lymphoid leukemias of mice.
1950 • 29 citations
STUDIES ON THE TOXICITY AND ANTILEUKEMIC ACTION OF 6‐MERCAPTOPURINE IN MICE
1954 • 27 citations
CLINICAL EXPERIENCE WITH 6‐MERCAPTOPURINE IN HUMAN NEOPLASIA
1954 • 26 citations
Effects of thioguanine in mammals
1956 • 24 citations
Clinical Evaluation of Puromycin in Human neoplastic Disease
1955 • 23 citations
Preliminary studies on the clinical toxicity of 5-amino-7-hydroxy-l-v-triazolo[d]-pyrimidine (guanazolo)
1949 • 23 citations
EFFECTS OF 6‐MERCAPTOPURINE ON EXPERIMENTAL TUMORS
1954 • 23 citations
EFFECTS OF 6-MERCAPTOPURINE ON EXPERIMENTAL TUMORS IN TISSUE CULTURE
1954 • 22 citations
Resistance in Leukemic Cells to a Guanine Analog, 8-Azaguanine
1951 • 22 citations
THE BIOSYNTHESIS OF NUCLEIC ACIDS AS A BASIS FOR AN APPROACH TO CHEMOTHERAPY
1954 • 21 citations
STATISTICAL ANALYSIS OF CLINICAL RESULTS FROM 6‐MERCAPTOPURINE
1954 • 21 citations
Response of Patients with Leukemia to 8-Azaguanine
1955 • 20 citations
THE THERAPEUTIC EFFECT OF MERCAPTOPURINE IN A VARIETY OF HUMAN NEOPLASTIC DISEASES
1954 • 19 citations
ADENINE: ITS FAILURE TO STIMULATE HEMOPOIESIS OR TO PRODUCE PELLAGRA IN A CASE OF PERNICIOUS ANEMIA
1948 • 14 citations
THE EFFECTS OF 6‐MERCAPTOPURINE, 8‐AZAGUANINE, AND 1,4‐DIMETHANESULFONYLOXYBUTANE ON AN EXPERIMENTAL BRAIN TUMOR: PRELIMINARY OBSERVATIONS
1954 • 12 citations
Observations on the effects of administration of guanazolo in patients with disseminated neoplasms
1952 • 8 citations
Relationship of Nucleic Acid Anabolism to the Treatment of Cancer
1956 • 7 citations
Cited By (0)
No citing papers found in database