Genetic analysis of human p34CDC2 function in fission yeast

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2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

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1988 • 5,115 citations

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1991 • 3,691 citations

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1983 • 3,302 citations

Universal control mechanism regulating onset of M-phase

1990 • 2,882 citations

Cyclin synthesis drives the early embryonic cell cycle

1989 • 1,223 citations

Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2

1987 • 1,153 citations

The role of cyclin synthesis and degradation in the control of maturation promoting factor activity

1989 • 1,114 citations

Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog

1987 • 1,004 citations

cdc25+ functions as an inducer in the mitotic control of fission yeast

1986 • 973 citations

Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe

1976 • 906 citations

mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2

1991 • 688 citations

Regulation of p34cdc2 protein kinase during mitosis

1989 • 544 citations

Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins

1991 • 509 citations

The cell cycle control gene cdc2+ of fission yeast encodes a protein kinase potentially regulated by phosphorylation

1986 • 502 citations

Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication

1990 • 460 citations

Phosphorylation at Thr167 is required for Schizosaccharomyces pombe p34cdc2 function.

1991 • 459 citations

Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2.

1990 • 352 citations

High-frequency transformation of the fission yeast Schizosaccharomyces pombe

1981 • 351 citations

Fission yeast p107wee1 mitotic inhibitor is a tyrosine/serine kinase

1991 • 344 citations

p80cdc25 mitotic inducer is the tyrosine phosphatase that activates p34cdc2 kinase in fission yeast.

1991 • 342 citations

Sequence of the cell division gene CDC2 from Schizosaccharomyces pombe; patterns of splicing and homology to protein kinases

1984 • 313 citations

Cell division cycle mutants altered in DNA replication and mitosis in the fission yeast Schizosaccharomyces pombe

1981 • 309 citations

The cdc25 M-phase inducer: An unconventional protein phosphatase

1992 • 266 citations

Mitochondrial growth and DNA synthesis occur in the absence of nuclear DNA replication in fission yeast

1990 • 266 citations

Cloning and sequencing of the cyclin-related Cdc13 + gene and a cytological study of its role in fission yeast mitosis

1988 • 220 citations

Wee1+-like gene in human cells

1991 • 211 citations

An additional homolog of the fission yeast cdc25+ gene occurs in humans and is highly expressed in some cancer cells.

1991 • 196 citations

Human cDNAs encoding homologs of the small p34Cdc28/Cdc2-associated protein of Saccharomyces cerevisiae and Schizosaccharomyces pombe.

1990 • 181 citations

Interaction between cdc13+ and cdc2+ in the control of mitosis in fission yeast; dissociation of the G1 and G2 roles of the cdc2+ protein kinase.

1987 • 177 citations

suc1 is an essential gene involved in both the cell cycle and growth in fission yeast

1986 • 165 citations

Isolation of cell size mutants of a fission yeast by a new selective method: characterization of mutants and implications for division control mechanisms

1981 • 110 citations

Molecular cloning and sequence analysis of mutant alleles of the fission yeast cdc2 protein kinase gene: Implications for cdc2 + protein structure and function

1989 • 88 citations

Regulation of p34cdc2 protein kinase: new insights into protein phosphorylation and the cell cycle

1991 • 65 citations

Conservation of function and regulation within the Cdc28/cdc2 protein kinase family: characterization of the human Cdc2Hs protein kinase in Saccharomyces cerevisiae.

1989 • 50 citations

Mutational analysis of the fission yeast p34cdc2 protein kinase gene

1993 • 34 citations

Expression of a dominant negative allele of cdc2 prevents activation of the endogenous p34cdc2 kinase

1991 • 30 citations

Conservation of Function and Regulation within the Cdc28/cdc2 Protein Kinase Family: Characterization of the Human Cdc2Hs Protein Kinase in Saccharomyces cerevisiae

1989 • 17 citations

Controlling cell cycle progress in the fission yeast Schizosaccharomyces pombe

1991 • 8 citations