Interleukin-11: a multifunctional growth factor derived from the hematopoietic microenvironment

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Conditions controlling the proliferation of haemopoietic stem cells in vitro

1977 • 2,157 citations

Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system.

1987 • 802 citations

IL-6-Induced Homodimerization of gp130 and Associated Activation of a Tyrosine Kinase

1993 • 730 citations

Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine.

1990 • 649 citations

LIFRβ and gp130 as Heterodimerizing Signal Transducers of the Tripartite CNTF Receptor

1993 • 632 citations

Neuropoietic cytokines in the hematopoietic fold

1991 • 474 citations

Cytokine regulation of neuronal differentiation of hippocampal progenitor cells

1993 • 307 citations

Involvement of IL-6 signal transducer gp130 in IL-11-mediated signal transduction.

1993 • 267 citations

Direct and synergistic effects of interleukin 11 on murine hemopoiesis in culture.

1991 • 234 citations

Growth factor requirements for survival in G0 and entry into the cell cycle of primitive human hemopoietic progenitors.

1992 • 224 citations

Interleukin-11 regulates the hepatic expression of the same plasma protein genes as interleukin-6.

1991 • 207 citations

Interleukin-11 enhances human megakaryocytopoiesis in vitro

1992 • 203 citations

Enhancement of murine hematopoiesis by synergistic interactions between steel factor (ligand for c-kit), interleukin-11, and other early acting factors in culture

1992 • 167 citations

Clonal proliferation of murine lymphohemopoietic progenitors in culture.

1992 • 163 citations

A bone marrow stromal-derived growth factor, interleukin-11, stimulates recovery of small intestinal mucosal cells after cytoablative therapy

1994 • 161 citations

Molecular cloning of cDNA encoding adipogenesis inhibitory factor and identity with interleukin‐11

1991 • 156 citations

Effects of recombinant interleukin 11 on human megakaryocyte progenitor cells.

1991 • 151 citations

Effects of recombinant human interleukin-11 on hematopoietic reconstitution in transplant mice: acceleration of recovery of peripheral blood neutrophils and platelets

1993 • 139 citations

Interleukin-11, an inducible cytokine in human articular chondrocytes and synoviocytes, stimulates the production of the tissue inhibitor of metalloproteinases.

1993 • 133 citations

The hematopoietic microenvironment

1991 • 121 citations

Enhancement of in vitro and in vivo antigen-specific antibody responses by interleukin 11.

1992 • 115 citations

Stromal cell-associated hematopoiesis: immortalization and characterization of a primate bone marrow-derived stromal cell line

1991 • 77 citations

Synergistic effects of interleukin 3 and interleukin 11 on murine megakaryopoiesis in serum-free culture.

1992 • 74 citations

Generation of murine stromal cell lines supporting hematopoietic stem cell proliferation by use of recombinant retrovirus vectors encoding simian virus 40 large T antigen.

1988 • 68 citations

Systematic analysis of the ability of stromal cell lines derived from different murine adult tissues to support maintenance of hematopoietic stem cells in vitro

1990 • 66 citations

Progenitor cell hyperplasia with rare development of myeloid leukemia in interleukin 11 bone marrow chimeras.

1993 • 65 citations

Effect of recombinant human interleukin‐11 on rat megakaryopoiesis and thrombopoiesis in vivo: comparative study with interleukin‐6

1993 • 65 citations

Interleukin-11 promotes accessory cell-dependent B-cell differentiation in humans

1992 • 63 citations

Lack of a role of interleukin 11 in the growth of multiple myeloma

1992 • 43 citations

Physiological mechanisms of stem cell regulation in bone marrow transplantation and haemopoiesis.

1989 • 40 citations

Adipogenesis inhibitory factor A novel inhibitory regulator of adipose conversion in bone marrow

1991 • 39 citations

Effect of Interleukin-11 on the Levels of mRNAs Encoding Heme Oxygenase and Haptoglobin in Human HepG2 Hepatoma Cells

1993 • 34 citations

Generation of Murine Stromal Cell Lines Supporting Hematopoietic Stem Cell Proliferation by Use of Recombinant Retrovirus Vectors Encoding Simian Virus 40 Large T Antigen

1988 • 26 citations

A bone marrow stromal-derived growth factor, interleukin-11, stimulates recovery of small intestinal mucosal cells after cytoablative therapy

1994 • 17 citations

Stromal cell-associated hematopoiesis: immortalization and characterization of a primate bone marrow-derived stromal cell line

1991 • 12 citations

Interleukin-11 enhances human megakaryocytopoiesis in vitro

1992 • 9 citations

Enhancement of murine hematopoiesis by synergistic interactions between steel factor (ligand for c-kit), interleukin-11, and other early acting factors in culture

1992 • 8 citations

In vivo effects of recombinant interleukin-11 on myelopoiesis in mice

1993 • 7 citations

Hematopoietic Microenvironments

2020 • 5 citations

Synergistic interactions between interleukin-11 and interleukin-4 in support of proliferation of primitive hematopoietic progenitors of mice

1991 • 4 citations

Effects of interleukin-11 on the proliferation and cell cycle status of myeloid leukemic cells

1993 • 3 citations