Endothelial superoxide production in the isolated rat heart during early reperfusion after ischemia. A histochemical study.

THF EARLY STAGES OF ABSORPTION OF INJECTED HORSERADISH PEROXIDASE IN THE PROXIMAL TUBULES OF MOUSE KIDNEY: ULTRASTRUCTURAL CYTOCHEMISTRY BY A NEW TECHNIQUE

1966 • 6,585 citations

Oxygen-Derived Free Radicals in Postischemic Tissue Injury

1985 • 5,488 citations

Biology of disease: free radicals and tissue injury.

1982 • 3,078 citations

Superoxide Dismutases

1975 • 1,673 citations

Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

1980 • 1,609 citations

Cerebral ischemia. II. The no-reflow phenomenon.

1968 • 1,346 citations

Direct measurement of free radical generation following reperfusion of ischemic myocardium.

1987 • 1,185 citations

Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog.

1983 • 1,168 citations

Role of metals in oxygen radical reactions

1985 • 1,149 citations

Canine myocardial reperfusion injury. Its reduction by the combined administration of superoxide dismutase and catalase.

1984 • 915 citations

NONDROPLET ULTRASTRUCTURAL DEMONSTRATION OF CYTOCHROME OXIDASE ACTIVITY WITH A POLYMERIZING OSMIOPHILIC REAGENT, DIAMINOBENZIDINE (DAB)

1968 • 892 citations

Role of neutrophils in ischemia-reperfusion-induced microvascular injury

1987 • 704 citations

Xanthine oxidase as a source of free radical damage in myocardial ischemia

1985 • 678 citations

Xanthine oxidase: biochemistry, distribution and physiology.

1986 • 635 citations

Direct detection of free radicals in the reperfused rat heart using electron spin resonance spectroscopy.

1987 • 628 citations

Measurement of endothelial cell free radical generation: evidence for a central mechanism of free radical injury in postischemic tissues.

1988 • 610 citations

Role of oxygen in the cellular damage induced by re-oxygenation of hypoxic heart

1980 • 550 citations

Molecular oxygen: Friend and foe*The role of the oxygen free radical system in the calcium paradox, the oxygen paradox and ischemia/reperfusion injury

1984 • 543 citations

The role of lipid peroxidation in pathogenesis of ischemic damage and the antioxidant protection of the heart

1982 • 523 citations

Mechanisms of Cell Injury by Activated Oxygen Species

1994 • 501 citations

Abrupt reoxygenation of the anoxic potassium-arrested perfused rat heart: A study of myocardial enzyme release

1973 • 443 citations

Localization of xanthine oxidase in mammary-gland epithelium and capillary endothelium

1981 • 435 citations

The scavenging of superoxide radical by manganous complexes: In vitro

1982 • 416 citations

Detection of superoxide generated by endothelial cells.

1984 • 398 citations

Oxygen-derived radicals: a link between reperfusion injury and inflammation.

1987 • 389 citations

Stereology: applications to biomedicalresearch.

1971 • 387 citations

Oxygen-mediated myocardial damage during ischameia and reperfusion: Role of the cellular defences against oxygen toxicity

1985 • 384 citations

Superoxide dismutase plus catalase improve contractile function in the canine model of the "stunned myocardium".

1986 • 360 citations

Identification of free radicals in myocardial ischemia/reperfusion by spin trapping with nitrone DMPO

1987 • 357 citations

Superoxide dismutase plus catalase enhances the efficacy of hypothermic cardioplegia to protect the globally ischemic, reperfused heart

1982 • 355 citations

Role of oxygen radicals in cardiac injury due to reoxygenation*

1984 • 276 citations

Improvement of postischemic myocardial function and metabolism induced by administration of deferoxamine at the time of reflow: the role of iron in the pathogenesis of reperfusion injury.

1987 • 249 citations

Xanthine oxidase type D (dehydrogenase) in the intestine and other organs of the rat

1972 • 201 citations

Myocardial ischemia and reperfusion: direct evidence for free radical generation by electron spin resonance spectroscopy.

1988 • 200 citations

Free radical-producing enzyme, xanthine oxidase, is undetectable in human hearts

1987 • 199 citations

Reduction of the size of infarction by allopurinol in the ischemic-reperfused canine heart.

1986 • 193 citations

Failure of superoxide dismutase and catalase to alter size of infarction in conscious dogs after 3 hours of occlusion followed by reperfusion.

1986 • 189 citations

Reperfusion injury: laboratory artifact or clinical dilemma?

1986 • 174 citations

Involvement of hydrogen peroxide and hydroxyl radical in the ‘oxygen paradox’: Reduction of creatine kinase release by catalase, allopurinol or deferoxamine, but not by superoxide dismutase**

1985 • 168 citations

Superoxide anion release by human endothelial cells: Synergism between a phorbol ester and a calcium ionophore

1986 • 165 citations

Inhibition of superoxide dismutases by azide

1978 • 149 citations

The oxygen free radical system: Potential mediator of myocardial injury

1985 • 146 citations

Superoxide release by neutrophils: Synergistic effects of a phorbol ester and a calcium ionophore

1984 • 129 citations

Superoxide production by polymorphonuclear leukocytes

1986 • 117 citations

Role of iron ions in the genesis of reperfusion injury following successful cardiopulmonary resuscitation: Preliminary data and a biochemical hypothesis

1985 • 104 citations

CYTOCHEMICAL LOCALIZATION OF PEROXIDASE ACTIVITY IN RAT HEPATIC MICROBODIES (PEROXISOMES)

1968 • 100 citations

Oxidation of manganous pyrophosphate by superoxide radicals and illuminated spinach chloroplasts

1976 • 97 citations

Infarct size limitation by the xanthine oxidase inhibitor, allopurinol, in closed-chest dogs with small infarcts

1985 • 97 citations

A novel superoxide radical generator in heart mitochondria

1987 • 94 citations

Protection from reperfusion injury in the isolated rat heart by postischaemic deferoxamine and oxypurinol administration

1987 • 79 citations

Comparison of horseradish peroxidase visualization methods: quantitative results and further technical specifics.

1981 • 77 citations

Extracellular matrix-cytoskeletal interactions in vascular cells

1987 • 53 citations

Cerium chloride as a histochemical marker of hydrogen peroxide in reperfused ischemic hearts

1990 • 50 citations

Serum malondialdehyde-like material (MDA-LM) in acute myocardial infarction.

1983 • 49 citations

Oxidative cytochemistry in phagocytosis: the interface between structure and function

1981 • 41 citations

Animal Models of Oxidant Lung Injury

1986 • 27 citations

Reperfusion injury of postischemic tissues

1988 • 26 citations

Glomerular mesangial and endothelial cell swelling following temporary renal ischemia and its role in the no-reflow phenomenon.

1977 • 25 citations

Transition metal-catalysed oxidation of 3,3′-diaminobenzidine [DAB] in a model system

1982 • 16 citations

Reperfusion arrhythmia: Myth or reality?

1989 • 14 citations

Cytochemical studies of hydrogen peroxide generation in postischemic hepatocytes

1991 • 11 citations

Glutathione disulfide formation and lipid peroxidation during cardiac ischemia and reflow in the dog in vivo

1989 • 11 citations

Neutrophil-endothelial interactions: Modulation of neutrophil activation responses by endothelial cells

1987 • 9 citations