Odd chromosome movement and inaccurate chromosome distribution in mitosis and meiosis after treatment with protein kinase inhibitors

Genistein, a specific inhibitor of tyrosine-specific protein kinases.

1987 • 3,773 citations

Kinetochores are transported poleward along a single astral microtubule during chromosome attachment to the spindle in newt lung cells.

1990 • 488 citations

Control of microtubule dynamics and length by cyclin A- and cyclin B-dependent kinases in Xenopus egg extracts.

1992 • 419 citations

CHROMOSOME MICROMANIPULATION

1969 • 367 citations

Kinetochores capture astral microtubules during chromosome attachment to the mitotic spindle: direct visualization in live newt lung cells.

1990 • 312 citations

The centromere-kinetochore complex: a repeat subunit model.

1991 • 283 citations

Properties of the kinetochore in vitro. II. Microtubule capture and ATP-dependent translocation.

1985 • 239 citations

Aneuploidy: Etiology and mechanisms

1987 • 204 citations

Human chromosomes and centrioles as nucleating sites for the in vitro assembly of microtubules from bovine brain tubulin.

1975 • 164 citations

The role of tyrosine phosphorylation in signal transduction through surface Ig in human B cells. Inhibition of tyrosine phosphorylation prevents intracellular calcium release.

1991 • 163 citations

PDGF-Induced Activation of Phospholipase C Is Not Required for Induction of DNA Synthesis

1990 • 158 citations

Formation of spindle fibers, kinetochore orientation, and behavior of the nuclear envelope during mitosis in endosperm

1969 • 156 citations

Chromosome motion during attachment to the vertebrate spindle: initial saltatory-like behavior of chromosomes and quantitative analysis of force production by nascent kinetochore fibers.

1991 • 149 citations

Properties of the kinetochore in vitro. I. Microtubule nucleation and tubulin binding.

1985 • 143 citations

Control of programmed cyclin destruction in a cell-free system.

1989 • 138 citations

Cellular mechanisms of chromosome distribution.

1970 • 137 citations

6-Dimethylaminopurine blocks starfish oocyte maturation by inhibiting a relevant protein kinase activity

1988 • 133 citations

Tyrosine phosphorylation of p34cdc2 and p42 during meiotic maturation of Xenopus oocyte: Antagonistic action of okadaic acid and 6-DMAP

1991 • 128 citations

Tubulin hooks as probes for microtubule polarity: an analysis of the method and an evaluation of data on microtubule polarity in the mitotic spindle.

1984 • 123 citations

Origin of kinetochore microtubules in Chinese hamster ovary cells

1980 • 119 citations

Spindle microtubules and their mechanical associations after micromanipulation in anaphase.

1982 • 116 citations

6-Dimethylaminopurine (6-DMAP), a reversible inhibitor of the transition to metaphase during the first meiotic cell division of the mouse oocyte

1989 • 113 citations

Microtubules, chromosome movement, and reorientation after chromosomes are detached from the spindle by micromanipulation

1985 • 106 citations

Tension, microtubule rearrangements, and the proper distribution of chromosomes in mitosis

1989 • 99 citations

Inhibition of mitosis by okadaic acid: possible involvement of a protein phosphatase 2A in the transition from metaphase to anaphase

1992 • 89 citations

Electron microscopy of spermatocytes previously studied in life: methods and some observations on micromanipulated chromosomes

1979 • 76 citations

Effect of genistein, a tyrosine kinase inhibitor, on U46619-induced phosphoinositide phosphorylation in human platelets

1990 • 68 citations

Cleavage inhibition in marine eggs by puromycin and 6-dimethylaminopurine

1973 • 65 citations

Formation of the astral mitotic spindle: Ultrastructural basis for the centrosome-kinetochore interaction

1990 • 63 citations

Mitosis: towards a molecular understanding of chromosome behavior

1991 • 57 citations

Mechanically cut mitotic spindles: clean cuts and stable microtubules

1989 • 51 citations

A requirement for protein phosphorylation in regulating the meiotic and mitotic cell cycles in echinoderms

1989 • 51 citations

Chromosome mal‐orientation and reorientation during mitosis

1992 • 36 citations

Induction of partial mitosis in BHK cells by 2-aminopurine

1991 • 33 citations

Effects of 6-dimethylaminopurine on microtubules and putative intermediate filaments in sea urchin embryos

1991 • 23 citations

Characterization of mitotic motors by their relative sensitivity to amp-pnp

1989 • 22 citations

Progress in video microscopy

1988 • 19 citations