Transport of Cationized Anti‐Tetanus Fab'2 Fragments Across an In Vitro Blood‐Brain Barrier Model: Involvement of the Transcytosis Pathway

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

1978 • 4,673 citations

Growth and cultivation of dissociated neurons and glial cells from embryonic chick, rat and human brain in flask cultures.

1972 • 760 citations

An Easier, Reproducible, and Mass‐Production Method to Study the Blood–Brain Barrier In Vitro

1990 • 534 citations

A New Function for the LDL Receptor: Transcytosis of LDL across the Blood–Brain Barrier

1997 • 531 citations

Botulinum Neurotoxin and Tetanus Toxin

1989 • 393 citations

Absorptive-mediated endocytosis of cationized albumin and a beta-endorphin-cationized albumin chimeric peptide by isolated brain capillaries. Model system of blood-brain barrier transport.

1987 • 314 citations

Drug Transfer Across the Blood‐Brain Barrier: Correlation Between In Vitro and In Vivo Models

1992 • 289 citations

Blood-brain barrier transport of cationized immunoglobulin G: enhanced delivery compared to native protein.

1989 • 211 citations

Bovine Brain Endothelial Cells Express Tight Junctions and Monoamine Oxidase Activity in Long‐Term Culture

1989 • 210 citations

Transcytosis of macromolecules through the blood-brain barrier: a cell biological perspective and critical appraisal

1989 • 173 citations

Receptor-mediated transcytosis of transferrin through blood-brain barrier endothelial cells

1996 • 160 citations

Ultracytochemical characterization of anionic sites in the wall of brain capillaries

1989 • 154 citations

Neurospecific Binding, Internalization, and Retrograde Axonal Transport

1995 • 104 citations

Molecular mechanisms of action of bacterial protein toxins

1994 • 98 citations

Permeability and mechanism of albumin, cationized albumin, and glycosylated albumin transcellular transport across monolayers of cultured bovine brain capillary endothelial cells.

1989 • 90 citations

Inhibition of P-glycoprotein: rapid assessment of its implication in blood-brain barrier integrity and drug transport to the brain by an in vitro model of the blood-brain barrier.

1998 • 77 citations

Chimeric peptides as a vehicle for peptide pharmaceutical delivery through the blood-brain barrier

1987 • 76 citations

Ultrastructural study on transcapillary exchanges in the developing telencephalon of the chicken

1970 • 67 citations

Cationization of immunoglobulin G results in enhanced organ uptake of the protein after intravenous administration in rats and primate.

1991 • 53 citations

Enhanced endocytosis in cultured human breast carcinoma cells and in vivo biodistribution in rats of a humanized monoclonal antibody after cationization of the protein.

1998 • 36 citations

Cationization of a monoclonal antibody to the human immunodeficiency virus REV protein enhances cellular uptake but does not impair antigen binding of the antibody

1994 • 35 citations

In vitro reconstituted blood-brain barrier

1992 • 31 citations

Enhanced Endocytosis and Anti-Human Immunodeficiency Virus Type 1 Activity of Anti-rev Antibodies after Cationization

1994 • 25 citations

Tetanus toxin as a neurobiological tool to study mechanisms of neuronal cell death in the mammalian brain

1994 • 16 citations