Decreased cerebral response to inhibitory neurotransmission in alcoholics

Sequence and functional expression of the GABAA receptor shows a ligand-gated receptor super-family

1987 • 1,621 citations

Neuropsychopharmacology

1990 • 1,545 citations

The Synaptic Organization of the Brain

1980 • 759 citations

Structural and functional basis for GABAA receptor heterogeneity

1988 • 590 citations

High densities of benzodiazepine receptors in human cortical areas

1977 • 406 citations

Alcohol withdrawal reactions in mice: effects of drugs that modify neurotransmission.

1973 • 213 citations

Alterations in γ‐Aminobutyric Acid Receptor Sensitivity Following Acute and Chronic Ethanol Treatments

1980 • 188 citations

Chronic ethanol administration alters gamma-aminobutyric acid, pentobarbital and ethanol-mediated 36Cl- uptake in cerebral cortical synaptoneurosomes.

1988 • 184 citations

Decreased brain metabolism in neurologically intact healthy alcoholics

1992 • 184 citations

Acute effects of ethanol on regional brain glucose metabolism and transport

1990 • 182 citations

Prolonged ethanol inhalation decreases gamma-aminobutyric acidA receptor alpha subunit mRNAs in the rat cerebral cortex.

1991 • 169 citations

The effect of ethanol on GABAergic transmission

1983 • 154 citations

Positron emission tomography assessment of effects of benzodiazepines on regional glucose metabolic rate in patients with anxiety disorder

1987 • 117 citations

Chronic Ethanol Treatment Alters Brain Levels of γ‐Aminobutyric Acid_A Receptor Subunit mRNAs: Relationship to Genetic Differences in Ethanol Withdrawal Seizure Severity

1991 • 117 citations

Alcohol intoxication: ion channels and genetics

1989 • 116 citations

Anatomic connections of the fastigial nucleus to the rostral forebrain in the cat

1973 • 105 citations

Differential effects of chronic ethanol administration on GABAA receptor α1 and α6 subunit mRNA levels in rat cerebellum

1992 • 98 citations

Chronic ethanol administration increases the binding of the benzodiazepine inverse agonist and alcohol antagonist [3H]RO15-4513 in rat brain

1988 • 96 citations

Effects of Ro15-4513 and other benzodiazepine receptor inverse agonists on alcohol-induced intoxication in the rat.

1988 • 87 citations

Evidence for genetic correlation of hypnotic effects and cerebellar Purkinje neuron depression in response to ethanol in mice

1982 • 86 citations

Benzodiazepine Enhancement of γ‐Aminobutyric Acid‐Mediated Chloride Ion Flux in Rat Brain Synaptoneurosomes

1988 • 86 citations

Alcohols stimulate γ-aminobutyric acid receptor-mediated chloride uptake in brain vesicles: correlation with intoxication potency

1988 • 80 citations

Basal ganglia/limbic striatal and thalamocortical involvement in craving and loss of control in alcoholism

1990 • 79 citations

Decreased Neuronal Inhibition in Vitro After Long-Tterm Administration of Ethanol

1984 • 79 citations

Molecular models for recognition and activation at the benzodiazepine receptor: A review

1991 • 71 citations

Benzodiazepine concentrations in brain directly reflect receptor occupancy: studies of diazepam, lorazepam, and oxazepam

1990 • 66 citations

Ethanol and the benzodiazepine-GABA receptor-ionophore complex

1989 • 60 citations

Regional Distribution of the GABA_A/Benzodiazepine Receptor (α Subunit) mRNA in Rat Brain

1988 • 59 citations

Plasma GABA levels in chronic alcoholics

1985 • 46 citations

Chapter 29. New Directions in Positron Emission Tomography

1989 • 26 citations

Cerebral Computed Tomography: A Text Atlas, 2nd ed

1985 • 23 citations

Cerebellar role in the differential ethanol sensitivity of long sleep and short sleep mice

1983 • 17 citations