Molecular characterization of a beta zero-thalassemia resulting from a 1.4 kilobase deletion

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Human fetal gγ- and Aγ-globin genes: Complete nucleotide sequences suggest that DNA can be exchanged between these duplicated genes

1980 • 947 citations

Linkage of β-thalassaemia mutations and β-globin gene polymorphisms with DNA polymorphisms in human β-globin gene cluster

1982 • 937 citations

Polymorphism of DNA sequence adjacent to human beta-globin structural gene: relationship to sickle mutation.

1978 • 804 citations

The "beta-like-globin" gene domain in human erythroid cells.

1985 • 634 citations

Insertion of synthetic copies of human globin genes into bacterial plasmids

1978 • 350 citations

Cloning Human Fetal γ Globin and Mouse α-Type Globin DNA: Preparation and Screening of Shotgun Collections

1978 • 350 citations

Recombination at the human α-globin gene cluster: Sequence features and topological constraints

1987 • 345 citations

THE FUSION OF TWO PEPTIDE CHAINS IN HEMOGLOBIN LEPORE AND ITS INTERPRETATION AS A GENETIC DELETION

1962 • 331 citations

β-Globin gene inactivation by DNA translocation in γβ-thalassaemi

1983 • 266 citations

Analysis of the β-δ-globin gene loci in normal and hb lepore DNA: Direct determination of gene linkage and intergene distance

1978 • 260 citations

Unexpected relationships between four large deletions in the human β-globin gene cluster

1983 • 218 citations

A gene deletion ending within a complex array of repeated sequences 3' to the human beta-globin gene cluster.

1986 • 149 citations

Nucleotide sequence analysis of the delta beta-globin gene region in humans.

1983 • 144 citations

Specific sequences in native DNA that arrest synthesis by DNA polymerase alpha.

1982 • 125 citations

Restriction maps for twenty-one Charon vector phages

1980 • 100 citations

A Chinese^Gγ⁺(^Aγδβ)⁰thalassemia deletion: comparison to other deletions in the human β-globin gene cluster and sequence analysis of the breakpoints

1985 • 89 citations

Dutch β°‐thalassaemia: a 10 kilobase DNA deletion associated with significant γ‐chain production

1984 • 87 citations

Duplication followed by deletion accounts for the structure of an Indian deletion β^o-thalassemia gene

1982 • 72 citations

The DNA sequence of the 5′ flanking region of the human 0-gk bin gene: evolutionary conservation and polymorphic differences

1982 • 69 citations

Alpha zero-thalassemia due to recombination between the alpha 1-globin gene and an AluI repeat

1985 • 65 citations

Partial deletion of the 5' beta-globin gene region causes beta zero- thalassemia in members of an American black family

1984 • 64 citations

Analysis of an inversion within the human beta globin gene cluster

1985 • 62 citations

Molecular characterization of an atypical beta-thalassemia caused by a large deletion in the 5' beta-globin gene region.

1986 • 43 citations

Detection of a novel DNA polymorphism in the beta-globin gene cluster.

1984 • 42 citations