Factor IX is activated in vivo by the tissue factor mechanism

THE PREPARATION OF 131I-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY

1963 • 10,322 citations

Solid Phase Peptide Synthesis

1976 • 1,798 citations

Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque.

1989 • 1,233 citations

An Enzyme Cascade in the Blood Clotting Mechanism, and its Function as a Biochemical Amplifier

1964 • 1,099 citations

Waterfall Sequence for Intrinsic Blood Clotting

1964 • 1,088 citations

Statistical Quality Control and Routine Data Processing for Radioimmunoassays and Immunoradiometric Assays

1974 • 1,063 citations

Activation of factor IX by the reaction product of tissue factor and factor VII: additional pathway for initiating blood coagulation.

1977 • 791 citations

Solid‐Phase Peptide Synthesis

1969 • 624 citations

Isolation and characterization of a cDNA coding for human factor IX.

1982 • 415 citations

The pathophysiology of the prethrombotic state in humans: insights gained from studies using markers of hemostatic system activation

1987 • 395 citations

Studies of the prothrombin activation pathway utilizing radioimmunoassays for the F2/F1 + 2 fragment and thrombin--antithrombin complex

1982 • 269 citations

Activation of human factor IX (Christmas factor).

1978 • 258 citations

Regulation of Extravascular Coagulation by Microvascular Permeability

1985 • 258 citations

Statistical characterization of the random errors in the radioimmunoassay dose--response variable.

1976 • 244 citations

Aging-associated changes in indices of thrombin generation and protein C activation in humans. Normative Aging Study.

1987 • 199 citations

Comparison of bleeding tendency, factor XI coagulant activity, and factor XI antigen in 25 factor XI-deficient kindreds

1985 • 186 citations

Factor VII deficiency

1981 • 153 citations

Evidence for the presence of tissue factor activity on subendothelium

1989 • 141 citations

High gene frequency of factor XI (PTA) deficiency in Ashkenazi Jews

1978 • 133 citations

Detection of factor X activation in humans

1989 • 118 citations

The isolation and characterization of a specific antibody population directed against the prothrombin activation fragments F2 and F1 + 2.

1979 • 103 citations

Elevated factor Xa activity in the blood of asymptomatic patients with congenital antithrombin deficiency.

1985 • 103 citations

Factor IX antigen by radioimmunoassay. Abnormal factor IX protein in patients on warfarin therapy and with hemophilia B.

1977 • 95 citations

Procedures for the coagulation laboratory

1981 • 81 citations

Interaction of tissue factor and factor VII at the earliest phase of coagulation.

1965 • 71 citations

Human prothrombin metabolism in normal man and in hypocoagulable subjects

1969 • 52 citations

Analysis of Disappearance Time‐Curves After Single Injection of Labelled Proteins

1973 • 50 citations

Tissue Extract and the Contact Reaction in Blood Coagulation

1961 • 45 citations

Antithrombin III deficiency: decreased synthesis of a biochemically normal molecule

1982 • 43 citations

Studies with 131I-labelled antithrombin III in dogs

1980 • 21 citations