Indirect evidence for a strict negative control of S-adenosyl-<scp>l</scp>-methionine decarboxylase by spermidine in rat hepatoma cells

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

1,4-Diaminobutane (Putrescine), Spermidine, and Spermine

1976 • 1,203 citations

Amine synthesis in rapidly growing tissues: ornithine decarboxylase activity in regenerating rat liver, chick embryo, and various tumors.

1968 • 742 citations

Induction of tyrosine alpha-ketoglutarate transaminase by steroid hormones in a newly established tissue culture cell line.

1966 • 484 citations

Enzyme-Activated Irreversible Inhibitors

1979 • 420 citations

On the Role of S-Adenosyl-L-methionine in the Biosynthesis of Spermidine by Rat Prostate

1969 • 415 citations

Anti-proliferative properties of DL-α-difluoromethyl ornithine in cultured cells. A consequence of the irreversible inhibition of ornithine decarboxylase

1978 • 398 citations

Methyl glyoxal bis(guanylhydrazone) as a potent inhibitor of mammalian and yeast S-adenosylmethionine decarboxylases

1972 • 344 citations

Studies on the Degradation of Tyrosine Aminotransferase in Hepatoma Cells in Culture

1971 • 319 citations

Polyamines in Biomedical Research

1981 • 311 citations

Polyamines in Mammalian Biology and Medicine

1979 • 295 citations

Assay of protein in the presence of high concentrations of sulfhydryl compounds

1973 • 288 citations

The Biochemistry of Adenosylmethionine

1978 • 257 citations

L-Ornithine Decarboxylase: an Essential Role in Early Mammalian Embryogenesis

1980 • 239 citations

STRUCTURAL BASIS FOR INHIBITION OF PROTEIN SYNTHESIS BY EMETINE AND CYCLOHEXIMIDE BASED ON AN ANALOGY BETWEEN IPECAC ALKALOIDS AND GLUTARIMIDE ANTIBIOTICS

1966 • 223 citations

Biological Sciences: Stability of HeLa Cell mRNA in Actinomycin

1972 • 222 citations

Alpha-methyl ornithine, a potent competitive inhibitor of ornithine decarboxylase, blocks proliferation of rat hepatoma cells in culture.

1976 • 213 citations

Control of ornithine decarboxylase activity in stimulated human lymphocytes by putrescine and spermidine

1973 • 133 citations

Regulation of Protein Synthesis in Chick Oviduct

1973 • 131 citations

More Sensitive Automated Detection of Polyamines in Physiological Fluids and Tissue Extracts with o-Phthalaldehyde

1975 • 128 citations

Inhibition of EMT6 tumor growth by interference with polyamine biosynthesis ; Effects of α-difluoromethyl- ornithine, an irreversible inhibitor or ornithine decarboxylase

1980 • 117 citations

“Superinduction” of tyrosine aminotransferase by actinomycin D: a reevaluation

1975 • 110 citations

The isolation and preliminary characterization of somatic cell mutants resistant to the protein synthesis inhibitor—Emetine

1976 • 104 citations

Regulation of polyamine biosynthesis

1979 • 100 citations

Polyamine synthesis in the regenerating rat liver: Stimulation of S-adenosylmethionine decarboxylase, and spermidine and spermine synthases after partial hepatectomy

1972 • 88 citations

Analogs of ornithine as inhibitors of ornithine decarboxylase. New deductions concerning the topography of the enzyme's active site

1978 • 83 citations

The modulation of the induction of ornithine decarboxylase by spermine, spermidine and diamines

1978 • 80 citations

Control of Degradation and Synthesis of Induced Tyrosine Aminotransferase studied in Hepatoma Cells in Culture

1969 • 78 citations

Inhibitors of polyamine biosynthesis. 1. .alpha.-Methyl-(+-)-ornithine, an inhibitor of ornithine decarboxylase

1974 • 71 citations

Initial characterization of a HTC cell variant partially resistant to the anti-proliferative effect of ornithine decarboxylase inhibitors

1978 • 67 citations

Regulation of S-adenosylmethionine decarboxylase by polyamines in Ehrlich ascites-carcinoma cells grown in culture

1980 • 61 citations

Investigation of the turnover of rat liver S-adenosylmethionine decarboxylase using a specific antibody.

1979 • 60 citations

S-Adenosyl-L-methionine decarboxylase during lymphocyte transformation: Decreased degradation in the presence of a specific inhibitor

1973 • 57 citations

Effect of α-methyl ornithine on ornithine decarboxylase activity of rat hepatoma cells in culture

1977 • 56 citations

Identification of pyruvate in S-adenosylmethionine decarboxylase from rat liver.

1978 • 54 citations

Effects of diamines on ornithine decarboxylase activity in control and virally transformed mouse fibroblasts

1979 • 51 citations

Further Evidence against Post-transcriptional Control of Inducible Tyrosine Aminotransferase Synthesis in Cultured Hepatoma Cells

1973 • 48 citations

Purification and characterization of S-adenosyl-L-methionine decarboxylase from mouse mammary gland and liver

1979 • 42 citations

Differential inhibition of mammalian aminopropyltransferase activities

1978 • 37 citations

Inhibition of polyamine accumulation and cell proliferation by derivatives of diaminopropane in Ehrlich ascites cells grown in culture

1979 • 33 citations

Inhibition by derivatives of diguanidines of cell proliferation in Ehrlich ascites cells grown in cultures

1980 • 19 citations

The decarboxylation of S-adenosylmethionine by detergent-treated extracts of rat liver

1979 • 17 citations

Enzymic Decarboxylation of S-Adenosyl-L-methionine in Rat Liver: Possible Interaction of Putrescine with the Prosthetic Group.

1975 • 17 citations

Control of activity of S‐adenosylmethionine decarboxylase in muscle by spermidine

1980 • 16 citations

Putrescine and the regulation of decarboxylase in cultured mouse mammary gland

1980 • 15 citations

S-adenosylmethionine decarboxylase from human placenta

1977 • 12 citations

Formation of CO2 from the carboxyl group of S-adenosylmethionine by liver membrane-associated enzymes involves the demethylation-transsulphuration pathway

1978 • 7 citations