Mechanistic analysis of the (Na⁺, K⁺)ion-activated ATPase using new pseudosubstrates

Microdetermination of Phosphorus

1956 • 7,242 citations

Determination of protein: A modification of the lowry method that gives a linear photometric response

1972 • 5,490 citations

The influence of some cations on an adenosine triphosphatase from peripheral nerves

1957 • 2,211 citations

The Sodium Pump

1975 • 969 citations

[66] Pyruvate kinase from muscle

1955 • 724 citations

The Sodium-Potassium Adenosinetriphosphatase

1974 • 476 citations

Stoichiometry and Localization of Adenosine Triphosphate-dependent Sodium and Potassium Transport in the Erythrocyte

1964 • 355 citations

Binding of Adenosine Triphosphate to Sodium and Potassium Ion-stimulated Adenosine Triphosphatase

1971 • 349 citations

Studies on the Characterization of the Sodium-Potassium Transport Adenosine Triphosphatase

1973 • 305 citations

The stoicheiometry of the sodium pump

1967 • 300 citations

The connexion between active cation transport and metabolism in erythrocytes

1965 • 276 citations

Properties of the Two Polypeptides of Sodium- and Potassium-dependent Adenosine Triphosphatase

1972 • 267 citations

The (Na⁺+K⁺) activated enzyme system and its relationship to transport of sodium and potassium

1974 • 259 citations

Studies on the Characterization of the Sodium-Potassium Transport Adenosine Triphosphatase

1971 • 231 citations

The binding potential, a neglected linkage concept

1965 • 221 citations

Purification and characterization of (Na+ + K+)-ATPase IV. Estimation of the purity and of the molecular weight and polypeptide content per enzyme unit in preparations from the outer medulla of rabbit kidney

1974 • 211 citations

Purification and Characterization of and [3H]Ouabain Binding to the Transport Adenosine Triphosphatase from Outer Medulla of Canine Kidney

1973 • 210 citations

ATP hydrolysis associated with an uncoupled sodium flux through the sodium pump: evidence for allosteric effects of intracellular ATP and extracellular sodium

1976 • 204 citations

Ion transport and phosphoproteins of human red blood cells

1962 • 176 citations

The Role of Negative Cooperativity and Half-of-the-Sites Reactivity in Enzyme Regulation

1976 • 158 citations

Spectrophotometric Identification of an Active Site-specific Acyl Glyceraldehyde 3-Phosphate Dehydrogenase

1968 • 153 citations

Substrate sites of the (Na+ + K+)-dependent ATPase

1976 • 142 citations

Intestinal alkaline phosphatase. Catalytic properties and half of the sites reactivity

1974 • 126 citations

A Simple Digital‐Computer Program for Estimating the Parameters of the Hill Equation

1973 • 122 citations

Bovine kidney alkaline phosphatase. Catalytic properties, subunit interactions in the catalytic process, and mechanism of Mg2+ stimulation.

1975 • 118 citations

Molecular properties of purified (sodium + potassium)-activated adenosine triphosphatases and their subunits from the rectal gland of Squalus acanthias and the electric organ of Electrophorus electricus

1975 • 110 citations

Constitution and properties of axonal membranes of crustacean nerves

1975 • 108 citations

The Na+, K+-ATPase Membrane Transport System: Importance in Cellular Function

1972 • 102 citations

(Na+, K+)-Activated Adenosinetriphosphatase of Axonal Membranes, Cooperativity and Control. Steady-State Analysis

1976 • 102 citations

A Model for Active Transport of Sodium and Potassium Ions as Mediated by a Tetrameric Enzyme

1973 • 93 citations

Purification and characterization of (Na+ + K+-ATPase. II. Preparation by zonal centrifugation of highly active (Na+ + K+-ATPase from the outer medulla of rabbit kidneys

1971 • 86 citations

Magnetic Resonance and Kinetic Studies of the Mechanism of Sodium and Potassium Ion-activated Adenosine Triphosphatase

1974 • 79 citations

K+-dependent phosphatase activity observed in the presence of both adenosine triphosphate and Na+

1969 • 78 citations

Functionally distinct classes of K+ sites on the (Na+ + K+)- dependent ATPase

1975 • 75 citations

The reaction mechanism of the sodium pump

1975 • 73 citations

Phosphatase activity stimulated by Na+ plus K+: Implications for the (Na+ plus K+)-dependent adenosine triphosphatase

1970 • 69 citations

A kinetic description for sodium and potassium effects on (Na⁺+K⁺)‐adenosine triphosphatase: a model for a two‐nonequivalent site potassium activation and an analysis of multiequivalent site models for sodium activation

1974 • 58 citations

Sequence of Steps in the (Na + K)-Activated Enzyme System in Relation to Sodium and Potassium Transport

1971 • 54 citations

Negative cooperativity and half of the sites reactivity. Alkaline phosphatases of Escherichia coli with Zn²⁺, Co²⁺, Cd²⁺ , Mn²⁺ and Cu²⁺ ions in the active sites

1974 • 54 citations

Studies on the partial reactions catalyzed by the (Na2+ + L+-activated ATPase. I. Effects of simple anions and nucleoside triphosphates on the alkali-cation specificity of the p-nitrophenylphosphatase

1971 • 46 citations

Sodium+potassium-activated ATPase of mammalian brain regulation of phosphatase activity

1975 • 44 citations

Specific sodium-22 binding to a purified sodium + potassium adenosine triphosphatase. Inhibition by ouabain.

1976 • 40 citations

Transient kinetics of (Na+ + K+)-ATPase studied with a fluorescent substrate

1976 • 38 citations

Pseudoconservative transition: A two-state model for the co-operative behavior of oligomeric proteins

1975 • 28 citations

Escherichia coli alkaline phosphatase. Kinetic studies with the tetrameric enzyme

1972 • 24 citations

2,4-Dinitrophenyl Phosphate

1966 • 23 citations

ANALYSIS OF Na⁺, K⁺AND NUCLEOTIDE INTERACTIONS IN TERMS OF A HETEROTROPIC RELAXATION MODEL FOR (Na⁺-K⁺)-ATPase

1974 • 12 citations