Molecular heterogeneity in complete cytogenetic responders after interferon-α therapy for chronic myelogenous leukemia: low levels of minimal residual disease are associated with continuing remission

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

Prognostic discrimination in "good-risk" chronic granulocytic leukemia

1984 • 989 citations

Prognostic discrimination in "good-risk" chronic granulocytic leukemia

1984 • 919 citations

A New Prognostic Score for Survival of Patients With Chronic Myeloid Leukemia Treated With Interferon Alfa Writing Committee for the Collaborative CML Prognostic Factors Project Group

1998 • 823 citations

Interferon Alfa-2a as Compared with Conventional Chemotherapy for the Treatment of Chronic Myeloid Leukemia

1994 • 592 citations

Interferon Alfa-2b Combined with Cytarabine versus Interferon Alone in Chronic Myelogenous Leukemia

1997 • 565 citations

Detection of major bcr-abl gene expression at a very low level in blood cells of some healthy individuals

1995 • 481 citations

Randomized comparison of interferon-alpha with busulfan and hydroxyurea in chronic myelogenous leukemia. The German CML Study Group [see comments]

1994 • 467 citations

The Presence of Typical and Atypical BCR-ABL Fusion Genes in Leukocytes of Normal Individuals: Biologic Significance and Implications for the Assessment of Minimal Residual Disease

1998 • 457 citations

Prolonged Survival in Chronic Myelogenous Leukemia after Cytogenetic Response to Interferon-α Therapy

1995 • 446 citations

UK Medical Research Council randomised, multicentre trial of interferon-αn1 for chronic myeloid leukaemia: improved survival irrespective of cytogenetic response

1995 • 409 citations

Competitive polymerase chain reaction to estimate the number of BCR-ABL transcripts in chronic myeloid leukemia patients after bone marrow transplantation

1993 • 388 citations

Treatment of chronic myelogenous leukemia: current status and investigational options [see comments]

1996 • 192 citations

Quantification of residual disease in chronic myelogenous leukemia patients on interferon-alpha therapy by competitive polymerase chain reaction

1996 • 178 citations

POLYMERASE CHAIN REACTION FOR DETECTION OF RESIDUAL LEUKAEMIA

1989 • 152 citations

Early detection of relapse after bone marrow transplantation in patients with chronic myelogenous leukaemia

1993 • 129 citations

Detection of minimal residual disease by polymerase chain reaction in Philadelphia chromosome-positive chronic myelogenous leukemia following interferon therapy

1992 • 83 citations

Variable numbers of BCR‐ABL transcripts persist in CML patients who achieve complete cytogenetic remission with interferon‐α

1995 • 79 citations

Quantitative determination of the hybrid Bcr‐Abl RNA in patients with chronic myelogenous leukaemia under interferon therapy

1992 • 77 citations

Quantification of residual disease in Philadelphia-positive acute lymphoblastic leukemia: comparison of blood and bone marrow.

1995 • 74 citations

Conversion of interferon-induced, long-term cytogenetic remissions in chronic myelogenous leukemia to polymerase chain reaction negativity.

1998 • 65 citations

Linkage of proliferative and maturational abnormalities in chronic myelogenous leukemia and relevance to treatment.

1993 • 62 citations

Minimal Residual Disease after Bone Marrow Transplant for Chronic Myeloid Leukaemia Detected by the Polymerase Chain Reaction

1993 • 53 citations

Molecular response of CML patients treated with interferon‐α monitored by quantitative Southern blot analysis

1997 • 32 citations

BCR‐ABL‐positive progenitors in chronic myeloid leukaemia patients in complete cytogenetic remission after treatment with interferon‐α

1998 • 23 citations