Synergistic action of two murine monoclonal antibodies that inhibit ADP- induced platelet aggregation without blocking fibrinogen binding

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

The isolation of IgG from mammalian sera with the aid of caprylic acid

1969 • 874 citations

Exposure of platelet fibrinogen receptors by ADP and epinephrine.

1979 • 868 citations

A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombasthenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa.

1983 • 780 citations

Human platelets possess an inducible and saturable receptor specific for fibrinogen.

1979 • 713 citations

An Abnormal Platelet Glycoprotein Pattern in Three Cases of Glanzmann's Thrombasthenia

1974 • 445 citations

Platelet Membrane Defects in Glanzmann's Thrombasthenia

1977 • 391 citations

Molecular Defects in Interactions of Platelets with the Vessel Wall

1984 • 381 citations

Interaction of fibrinogen with its platelet receptor as part of a multistep reaction in ADP-induced platelet aggregation.

1980 • 373 citations

Correlation between fibrinogen binding to human platelets and platelet aggregability

1980 • 365 citations

Interrelations of Platelet Aggregation and Secretion

1977 • 350 citations

Factors responsible for ADP-induced release reaction of human platelets

1975 • 326 citations

Complex formation of platelet membrane glycoproteins IIb and IIIa with fibrinogen.

1982 • 324 citations

Specific and saturable binding of plasma fibronectin to thrombin-stimulated human platelets.

1981 • 300 citations

Inhibition of fibrinogen binding to stimulated human platelets by a monoclonal antibody.

1983 • 280 citations

Identification of two structurally and functionally distinct sites on human platelet membrane glycoprotein IIb-IIIa using monoclonal antibodies.

1983 • 241 citations

Identification of the fibrinogen receptor on human platelets by photoaffinity labeling.

1982 • 197 citations

Prostacyclin inhibits mobilisation of fibrinogen-binding sites on human ADP- and thrombin-treated platelets

1980 • 193 citations

Quantitation of membrane glycoprotein IIIa on intact human platelets using the monoclonal antibody, AP-3

1985 • 175 citations

On the association of glycoprotein Ib and actin-binding protein in human platelets.

1985 • 165 citations

A monoclonal antibody against human thrombospondin inhibits platelet aggregation.

1985 • 152 citations

Comparison of fibrinogen association with normal and thrombasthenic platelets on exposure to ADP or chymotrypsin

1979 • 138 citations

Redistribution of the fibrinogen receptor of human platelets after surface activation.

1984 • 133 citations

The different glycoprotein abnormalities in thrombasthenic and Bernard-Soulier platelets.

1979 • 133 citations

Relationship between Fibrinogen Binding and the Platelet Glycoprotein Deficiencies in Glanzmann's Thrombasthenia Type I and Type II

1981 • 111 citations

Induction of the fibrinogen receptor on human platelets by epinephrine and the combination of epinephrine and ADP.

1980 • 107 citations

Participation of ADP in the binding of fibrinogen to thrombin- stimulated platelets

1980 • 86 citations

Shape and Functional Properties of Human Platelets Washed with Acid Citrate

1981 • 79 citations

Interaction of thrombospondin with resting and stimulated human platelets.

1986 • 72 citations

Interaction of fibrinogen with its platelet receptor: kinetics and effect of pH and temperature

1981 • 69 citations

Platelet aggregation and exposure of fibrinogen receptors by prostaglandin endoperoxide analogues

1983 • 69 citations

Immunocytochemical study of the binding of fibrinogen and thrombospondin to ADP- and thrombin-stimulated human platelets

1985 • 66 citations

Platelet activation detected by turbidometric shape-change analysis. Differential influence of cytochalasin B and prostaglandin E1

1978 • 66 citations

Inhibition of platelet aggregation by a monoclonal antibody against human fibronectin.

1985 • 56 citations

Platelet protein organization: analysis by treatment with membrane- permeable cross-linking reagents

1982 • 47 citations

An inherited platelet function defect in Basset hounds.

1979 • 35 citations

Evidence for interaction between platelet fibrinogen receptors

1982 • 16 citations

Two-dimensional electrophoretic studies of platelets from dogs affected with basset hound hereditary thrombopathy: A thrombasthenia-like aggregation defect

1986 • 10 citations