Chronic hypersensitivity pneumonitis produced in the rabbit by the adjuvant effect of inhaled muramyl dipeptide (MDP).

Increased production of superoxide anion by macrophages exposed in vitro to muramyl dipeptide or lipopolysaccharide.

1980 • 356 citations

Macrophage Activation by Mycobacterial Water Soluble Compounds and Synthetic Muramyl Dipeptide

1979 • 209 citations

Biological Activities of Muramyl Dipeptide, a Synthetic Glycopeptide Analogous to Bacterial Immunoregulating Agents (Part 1 of 2)

1978 • 201 citations

Components of mycobacteria and muramyl dipeptide with adjuvant activity induce lymphocyte activating factor

1980 • 181 citations

In vitro activation of tumoricidal properties in rat alveolar macrophages by synthetic muramyl dipeptide encapsulated in liposomes

1981 • 139 citations

Granulomatous Inflammations

2015 • 106 citations

Immunopathogenesis of hypersensitivity pneumonitis.

1977 • 103 citations

Inhibition of macrophage migration by muramyl peptides

1979 • 73 citations

Adjuvant polyarthritis. V. Induction by N-acetylmuramyl-L-alanyl-D-isoglutamine, the smallest peptide subunit of bacterial peptidoglycan.

1981 • 60 citations

Experimental production of granulomatous pneumonitis *1Comparison of immunological and morphological sequelae with particulate and soluble antigens administered via the respiratory route

1975 • 59 citations

Arthritis-inducing ability of a synthetic adjuvant, N-acetylmuramyl peptides, and bacterial disaccharide peptides related to different oil vehicles and their composition

1980 • 58 citations

Amplification of the enzyme-linked immunosorbent assay (ELISA) in the detection of class-specific antibodies

1978 • 58 citations

Minimum structural requirements for encephalitogen and for adjuvant in the induction of experimental allergic encephalomyelitis

1978 • 55 citations

In vivo regulation of humoral and cellular immune reponses of mice by a synthetic adjuvant, N-acetyl-muramyl-l-alanyl-d-isoglutamine, muramyl dipeptide for MDP

1979 • 53 citations

Macrophage Activation by Muramyl Dipeptide as Measured by Macrophage Spreading and Attachment

1980 • 50 citations

Acute experimental hypersensitivity pneumonitis in the guinea pig.

1972 • 50 citations

An animal model of hypersensitivity pneumonitis in the rabbit.

1975 • 47 citations

Bronchopulmonary Macrophage Activation in the Pathogenesis of Hypersensitivity Pneumonitis

1978 • 46 citations

The adjuvant activity of synthetic N-acetylmuramyl-dipeptide: Evidence of initial target cells for the adjuvant activity

1979 • 40 citations

Chronic experimental interstitial pneumonitis in the rabbit.

1978 • 39 citations

VARIETIES OF ACUTE IMMUNOLOGIC DAMAGE TO THE RABBIT LUNG *

1974 • 37 citations

Hypersensitivity Pneumonitis: Current Concepts of Etiology and Pathogenesis

1976 • 37 citations

Acute experimental hypersensitivity pneumonitis in rabbits.

1971 • 37 citations

Experimental production of hypersensitivity pneumonitis with bagasse and thermophilic actinomycete antigen

1972 • 36 citations

Antigen-specific densensitization in a rabbit model of acute hypersensitivity pneumonitis

1981 • 36 citations

Systemic and Local Lymphocyte Responses in Experimental Hypersensitivity Pneumonitis^1–3

1980 • 25 citations

In vivo responses to inhaled proteins. II. Induction of interstitial pneumonitis and enhancement of immune complex-mediated alveolitis by inhaled concanavalin A.

1979 • 24 citations

Cellular and humoral bronchopulmonary immune response of rabbits immunized with thermophilic actinomyces antigen.

1976 • 23 citations

An animal model of hypersensitivity pneumonitis in the rabbit. Induction of cellular hypersensitivy to inhaled antigens using carrageenan and BCG.

1977 • 23 citations

Desensitization

1978 • 22 citations

Animal models of hypersensitivity pneumonitis: a review.

1977 • 21 citations

Stimulation of the in vivo dinitrophenyl antibody response to the DNP conjugate of L-glutamic acid60-L-alanine30-L-Tyrosine10 (GAT) polymer by a synthetic adjuvant, muramyl dipeptide (MDP): target cells for adjuvant activity and isotypic pattern of MDP-stimulated response.

1980 • 21 citations

In vivo responses to inhaled proteins. III. Inhibition of experimental immune complex pneumonitis after suppression of peripheral blood lymphocytes.

1980 • 17 citations

Inhibition of mitogen-induced polyclonal activation by by a synthetic adjuvant, muramyl dipeptide (MDP).

1980 • 12 citations

Cell-mediated immunity to soluble and particulate inhaled antigens.

1979 • 10 citations

An animal model of hypersensitivity pneumonitis in rabbits. Development of chronic pulmonary inflammation and cell-mediated hypersensitivity after repeated aerosol challenge.

1979 • 10 citations