Pharmacological Models in the Development of Antipsychotic Drugs — New Strategies

Prestimulus Effects on Human Startle Reflex in Normals and Schizophrenics

1978 • 1,173 citations

Identification and distribution of 5-HT3 receptors in rat brain using radioligand binding

1987 • 866 citations

Effects of the 5‐HT₃ receptor antagonist, GR38032F, on raised dopaminergic activity in the mesolimbic system of the rat and marmoset brain

1987 • 354 citations

Differential inhibitory effects of a 5-HT3 antagonist on drug-induced stimulation of dopamine release

1989 • 277 citations

Schizophrenic-like sensorimotor gating abnormalities in rats following dopamine infusion into the nucleus accumbens

1990 • 248 citations

The psychopharmacology of 5-HT3 receptors

1990 • 246 citations

Activation of a 5-HT3 receptor releases dopamine from rat striatal slice

1988 • 163 citations

5-HT3 receptors control dopamine release in the nucleus accumbens of freely moving rats

1989 • 153 citations

Effect of the 5-HT3 receptor antagonist, GR38032F, on responses to injection of a neurokinin agonist into the ventral tegmental area of the rat brain

1987 • 113 citations

[3H]Zacopride: Ligand for the Identification of 5-HT3 Recognition Sites

1988 • 112 citations

Effect of 5‐HT₃ receptor antagonists on responses to selective activation of mesolimbic dopaminergic pathways in the rat

1990 • 109 citations

Therapeutic potential of plant photosensitizers

1991 • 104 citations

Stress activation of limbic and cortical dopamine release is prevented by ICS 205-930 but not by diazepam

1990 • 74 citations

Behavioural and biochemical consequences of persistent overstimulation of mesolimbic dopamine systems in the rat

1982 • 70 citations

The Neurobiology of Dopamine Systems

1987 • 68 citations

The psychopharmacology and treatment of schizophrenia

1987 • 60 citations

The putative 5-HT3 agonist phenylbiguanide induces carrier-mediated release of [3H]dopamine

1989 • 57 citations

Laterality of dopamine function and neuroleptic action in the amygdala in the rat

1985 • 39 citations

The Psychopharmacology and treatment of schizophrenia

1986 • 28 citations

Actions of ORG 5222 as a novel psychotropic agent

1990 • 26 citations

Long-term consequences of antagonism by neuroleptics of behavioural events occurring during mesolimbic dopamine infusion

1984 • 19 citations

The neurobiology of dopamine systems

1986 • 17 citations

Analysis of the actions of 5-hydroxytryptamine on the rabbit isolated vagus nerve

1990 • 10 citations

Desenkephalin-γ-endorphin is an antagonist of the hyperactivity response induced by infusion of dopamine into the nucleus accumbens of rat and ventral striatum of marmoset

1989 • 2 citations